Using starch as a novel drug transporter
A special type of starch could soon be used as an excipient in medicine to improve the treatment of patients. A research team from Martin Luther University Halle-Wittenberg (MLU) has discovered that it makes a suitable drug release system and has adv.....»»
Common equine painkiller disrupts assisted reproduction technique efficiency in mares
Researchers at the Texas A&M School of Veterinary Medicine & Biomedical Sciences (VMBS) have discovered that phenylbutazone, a non-steroidal anti-inflammatory drug (NSAID) commonly prescribed in horses, can affect the ability of a mare's egg cells—.....»»
Study finds protein reduces toxicity of graphene oxide for drug delivery
A new study has discovered ways to reduce the toxicity of graphene oxide (GO), an ultra-thin sheet of nanomaterial derived from graphite, laying the groundwork to use it as a drug delivery system......»»
The FDA Just Rejected a Bid for MDMA to Treat PTSD
The agency has asked drugmaker Lykos Therapeutics to run an additional study on the use of the psychedelic drug in patients with post-traumatic stress disorder, pushing back its next proposal by years......»»
New ligand-guided technique enhances drug development
Achieving a level of precision to create complex medicines and materials with extreme accuracy is a longstanding goal of scientists and pharmaceutical companies. If achieved, that precision could lead to the development of more effective drug treatme.....»»
DNA Topoisomerase insights hold potential for drug discovery and plant protection
Insights into the function of DNA Topoisomerase VI (Topo VI) may provide a springboard for drug discovery and crop protection......»»
After AI, quantum computing eyes its "Sputnik" moment
Quantum computing promises society-changing breakthroughs in drug development and tackling climate change, and on an unassuming English high street, the race to unleash the latest tech revolution is gathering pace......»»
HomeKit Weekly: meross smart plug delivers almost everything you’d want in a HomeKit smart plug
Smart plugs are the gateway drug for HomeKit. They’re low-cost and easy to install, and you can get many benefits from them. There are dozens upon dozens of options on where to start, though. The smart plug delivers almost everything you’d want.....»»
Scientists "cautiously optimistic" about AI"s role in drug discovery
The human body contains at least 20,000 different proteins, often called the "workhorses of the cell" because of their role in keeping cells healthy. Each protein consists of a unique string of amino acids that affects its shape and function—or dys.....»»
Scientists reveal transport mechanism of norepinephrine transporter and binding mode of small molecule and peptide drugs
Noradrenaline (NA) is an important monoamine neurotransmitter in the nervous system. The noradrenaline transporter (NET) located on the presynaptic membrane can transport NA into presynaptic neurons......»»
Electrical impedance tomography plus extracellular voltage activation technique simplifies drug screening
When developing new drugs, understanding their effects on ion channels in the body, such as the human ether-a-go-go-related gene (hERG) ion channel found in neurons and heart muscle cells, is critical. Blocking hERG channels can disrupt a normal hear.....»»
"Russian doll" packaging could boost drug delivery
New technology, which is in the early stages of development, has the potential to significantly enhance the effectiveness and reduce the side effects of drugs and vaccines......»»
New and improved drug-delivery molecules for skeletal muscle
Researchers from Tokyo Metropolitan University have created a new drug-delivery molecule, a zwitterionic polymer complex that can help get plasmid DNA inside cells when injected into skeletal muscle, a crucial step in the expression of therapeutic RN.....»»
Research team develops new antimalarial agent for combating drug-resistant parasites
Malaria remains a serious health issue globally, especially in Africa. The disease is caused by protozoan parasites in the Plasmodium genus. In 2021, there were 247 million cases of malaria and 619,000 deaths reported worldwide......»»
Counter-drug strategies in Central America are worsening deforestation, threatening many species of birds
Activities associated with cocaine trafficking threaten two-thirds of the most important landscapes in Central America for 196 forest bird species, including 67 migratory species. This is the key takeaway from a study that colleagues and I published.....»»
Illegal drug found in Diamond Shruumz candies linked to severe illnesses
New testing finds psilocin, related to psilocybin, in gummies purchased in 2023. Enlarge (credit: Diamond Shruumz) Newly released testing data of Diamond Shruumz-brand gummies purchased in 2023 identified the presence of.....»»
De-risking drug discovery with predictive AI
Developing a new drug can take years of research and cost millions of dollars. Still, more than 90% of drug candidates fail in clinical trials, with even more that never make it to the clinical stage. Many drugs fail because they simply aren't safe......»»
Dynamic view of opioid receptor could refine pain relief
Effective pain relief without the debilitating side effects of traditional opioids is closer to becoming a reality thanks to a study by an all-RIKEN team into the structure and dynamics of a drug-bound opioid receptor......»»
Engineered nanovesicles from activated neutrophils show promise in treating infected wounds
Infectious wounds represent a critical challenge in health care, especially for diabetic patients grappling with ineffective antibiotics and escalating drug resistance. Conventional therapies often inadequately address deep tissue infections, highlig.....»»
The evolving single-cell and spatial technology landscape
The scTrends consortium has published its first report shedding light on the current state of the commercial single-cell and spatial genomics industry and its potential impact on drug discovery and patient care......»»
Chemists develop modular approach for creating important class of pharmaceutical compounds
Chemists at the National University of Singapore (NUS) have developed a modular approach to create 1,2-arylheteroaryl ethanes, a class of compounds important for drug discovery and pharmaceutical development, using fundamental feedstock chemicals suc.....»»