Electrical impedance tomography plus extracellular voltage activation technique simplifies drug screening
When developing new drugs, understanding their effects on ion channels in the body, such as the human ether-a-go-go-related gene (hERG) ion channel found in neurons and heart muscle cells, is critical. Blocking hERG channels can disrupt a normal hear.....»»
X-ray measurements reveal an unexpected role for copper in photocatalysts
Copper is a promising catalyst for sustainably converting carbon dioxide into substances with more electrons (called reduced species). This is an important step in converting carbon dioxide into fuels. This reaction is often initiated by electrical e.....»»
A molecular trap for exotic metals promises improved diagnostics and faster drug development
A group of scientists from IOCB Prague, led by Dr. Miloslav Polášek, have created compounds that are up to a million times more stable than similar substances used in contemporary medicine to treat tumors or as contrast agents for magnetic resonanc.....»»
Improved ultrasound technique produces previously unattainable images inside live cells
A ultrasound technique from the University of Nottingham will allow the production of sharper images inside live cells without causing damage at resolutions that were previously unattainable......»»
New technique points to unexpected uses for snoRNA across many cell types
Dynamic, reversible modifications of DNA and RNA regulate how genes are expressed and transcribed, which can influence cellular processes, disease development, and overall organismal health. Small nucleolar RNAs (snoRNAs) are a common but overlooked.....»»
A technique for estimating the mass of gigantic filaments of dark matter
How do you weigh one of the largest objects in the entire universe? Very carefully, according to new research......»»
From traditional to technological: Using laser Doppler vibrometry for fresco conservation
Fresco painting, a technique that dates back to antiquity, involves applying dry pigments to wet plaster, creating stunning artwork that can last for centuries. Over time, however, these masterpieces often face degradation due to delamination, where.....»»
Light-activated, drug-carrying liposomes show potential for minimally invasive glaucoma treatments
More than 4 million people in the U.S. have glaucoma, a group of eye diseases that can damage the optic nerve and lead to vision loss. It's the second-leading cause of blindness worldwide and there's currently no cure, but there's a way to help preve.....»»
Sugar-like nanoparticle covering could boost cancer drug delivery
A spoonful of sugar might actually help medicine go down, according to recent research from the University of Mississippi. And it could reduce the harmful side effects of cancer treatment. Instead of a literal spoonful of sugar, however, the research.....»»
Researchers develop pioneering monitoring technique to help build mangrove resilience
Mangroves are remarkable ecosystems home to amazing biodiversity, dense vegetation, and conditions that capture large quantities of carbon. Since they occur in warm, tropical, and subtropical coastal regions, they also take the brunt of the impact fr.....»»
Engineered antibiotic D22 shows promise against drug-resistant bacteria
Antibacterial drugs are important for treating infections. But increasingly, bacterial resistance to current drugs—so they don't work well, or even at all—means new ones are urgently needed......»»
Novo Nordisk sells hit weight-loss drug in China—at fraction of US price
As US struggles to afford GLP-1 drugs, the rest of the world sees much lower prices. Patients in China will be able to purchase the blockbuster weight-loss drug Wegovy for 1,400 y.....»»
Cross-IdP impersonation bypasses SSO protections
Cross-IdP impersonation – a technique that enables attackers to hijack the single sign-on (SSO) process to gain unauthorized access to downstream software-as-a-service (SaaS) applications without compromising a company’s primary identity.....»»
Splunk simplifies infrastructure requirements for Microsoft Azure customers
Splunk announced its enterprise security, observability and platform offerings on Microsoft Azure. In partnering with Microsoft, Splunk empowers organizations to scale their digital transformation on Azure with unified solutions that accelerate innov.....»»
Onapsis Secure RISE Accelerator streamlines security elements of modern SAP deployments
Onapsis announced the Onapsis Secure RISE Accelerator, helping organizations execute their RISE with SAP transformation with confidence. The new offering reduces security and compliance obstacles with a structured, bundled solution that simplifies an.....»»
CRISPR-based system labels extracellular vesicles with "barcodes" to better understand cell-to-cell communication
Cell-to-cell communication through nanosized particles, working as messengers and carriers, can now be analyzed in a whole new way, thanks to a new method involving CRISPR gene-editing technology......»»
Researchers characterize regulating mechanism of orderly zygotic genome activation in early embryos
Early development of an embryo is solely supported by maternally deposited RNAs and proteins until its own genome is activated through a process called zygotic genome activation (ZGA). Recent work by Chinese scientists has revealed a novel molecular.....»»
Hormone receptor structure reveals how it functions in heart disease
Weill Cornell Medicine researchers have determined the full-length structure of a blood pressure-regulating hormone receptor for the first time, uncovering how it functions, which may enable better drug targeting of the receptor for diseases such as.....»»
Scientists propose drug-free method to combat antibiotic-resistant bacteria
Recent estimates indicate that deadly antibiotic-resistant infections will rapidly escalate over the next quarter century. More than 1 million people died from drug-resistant infections each year from 1990 to 2021, a recent study reported, with new p.....»»
Mechanical metamaterial enables long-distance component interaction for unique stretching properties
Metamaterials are artificial materials that do not occur in nature. Their components function like atoms in conventional materials but have special optical, electrical and magnetic properties. Interaction between the components is crucial to a metama.....»»
Researchers Give Animal Cells the Ability to Photosynthesize for the First Time
A Japanese team has developed a technique to insert chloroplasts isolated from algae into animal cells, a feat that could revolutionize sustainable energy and how artificial meat and organs are created......»»