Using starch as a novel drug transporter
A special type of starch could soon be used as an excipient in medicine to improve the treatment of patients. A research team from Martin Luther University Halle-Wittenberg (MLU) has discovered that it makes a suitable drug release system and has adv.....»»
Rite Aid says breach exposes sensitive details of 2.2 million customers
Stolen data includes customer names, addresses, birth dates, and driver's license numbers. Enlarge / Rite Aid logo displayed at one of its stores. (credit: Getty Images) Rite Aid, the third biggest US drug store chain, s.....»»
Lab develops smallest free-floating bubbles for medical imaging
Bioengineering researchers at Rice University have developed ultrasmall, stable gas-filled protein nanostructures that could revolutionize ultrasound imaging and drug delivery......»»
New class of organic nanoparticles shows promise for diverse applications
Nanoparticles have a wide variety of applications, from drug delivery to electronics to air purification. Their small size and tunable properties make them particularly valuable for technological advancements and scientific research. When polymers ma.....»»
Research team develops light-activated compounds to treat neuropathic pain
Light can be used to activate drugs in specific parts of the body through photopharmacology. This innovative approach involves modifying the chemical structure of a drug by adding a light-activated molecular switch, such as azobenzene. This allows th.....»»
A comprehensive derivative synthesis method for development of new antimicrobial drugs
Efforts to combat the increasing threat of drug-resistant bacteria are being assisted by a new approach for streamlining the search for antimicrobial drug candidates, pioneered by researchers at Hokkaido University, led by Assistant Professor Kazuki.....»»
What Makes a Psychedelic Experience? Not Always a Drug, It Turns Out
A Stanford anesthesiologist deconstructs the component parts of what it means to undergo a psychedelic trip.....»»
We’re Not Asking the Right Question to Solve the Overdose Crisis
Drug policy continues to fixate on symptoms rather than the actual disease.....»»
Drug middlemen inflate US prices, squeeze out competition, FTC says
Pharmacy benefit managers (PBMs) are key part of US's high drug costs, report finds. Enlarge / Lina Khan, chair of the Federal Trade Commission (FTC), testifies before the House Appropriations Subcommittee at the Rayburn House O.....»»
New weight-loss and diabetes drugs linked to lower risk of 10 cancers
For diabetes patients, GLP-1 drugs linked to lower cancer risks compared to insulin. Enlarge / Ozempic is a GLP-1 drug for adults with type 2 diabetes. (credit: Getty | Steve Christo) For patients with Type 2 diabetes, t.....»»
First set of rational design principles for chaotropic membrane transporters
The challenge of internalizing impermeable molecules into cells persists in drug development, particularly concerning water-soluble bioactive compounds that cannot diffuse across the cell membrane. To overcome this problem, various artificial transpo.....»»
AI able to identify drug-resistant typhoid-like infection from microscopy images in matter of hours
Artificial intelligence (AI) could be used to identify drug resistant infections, significantly reducing the time it takes for a correct diagnosis, Cambridge researchers have shown. The team determined that an algorithm could be trained to identify d.....»»
Graph learning modules enhance drug-target interaction predictions
The identification of drug-target Interactions (DTIs) represents a pivotal link in the process of drug development and design. It plays a crucial role in narrowing the screening range of candidate drug molecules, thereby facilitating the reuse of dru.....»»
New mRNA technology turns cells into long-lasting drug factories
A team of researchers has established a ribonucleic acid (RNA)-based method that drives cells in the body to produce therapeutic proteins and secrete them into the bloodstream. The approach could potentially extend the lifespan of drugs in the body,.....»»
A new way to see viruses in action: Super-resolution microscopy provides a nano-scale look
A new, nano-scale look at how the SARS-CoV-2 virus replicates in cells may offer greater precision in drug development, a Stanford University team reports in Nature Communications. Using advanced microscopy techniques, the researchers produced what m.....»»
Scientists elucidate substrate recognition and proton coupling mechanism of transporter protein VMAT2
Vesicular monoamine transporter 2 (VMAT2) is the only transporter protein in the central nervous system that mediates the storage of monoamine neurotransmitters. It plays a critical role in mediating nerve impulse transmission and neuroprotection......»»
Drug trafficker wouldn’t get out of car, hinted something was inside, GA deputies say
Drug trafficker wouldn’t get out of car, hinted something was inside, GA deputies say.....»»
A synthetic drug ravages youth in Sierra Leone. There"s little help, and some people are chained
A synthetic drug ravages youth in Sierra Leone. There"s little help, and some people are chained.....»»
Unveiling a novel AAK1 inhibitor: How chemical proteomics unlock therapeutic potential
Enhancing drug development for life-threatening diseases like cancer hinges on a deep understanding of protein kinases, making it a focal point for researchers. These enzymes, encoded by more than 500 human genes, serve as critical players in cellula.....»»
The next food marketing blitz is aimed at people on new weight-loss drugs
Taking a weight-loss drug? Food makers have just the new food for you. Enlarge (credit: Getty | Jeffrey Greenberg) As new diabetes and weight-loss drugs help patients curb appetites and shed pounds, food manufacturers ar.....»»
How yeasts manage to compensate for the genetic imbalance of extra chromosomes
Having extra chromosomes is typically an issue for an organism and can disrupt development or cause disease. But some cells benefit instead. For example, cancer cells or pathogenic yeasts can use extra chromosomes to escape treatment and become drug-.....»»