Nano-drugs hitching a ride on bacteria could help treat pancreatic cancer
Many pancreatic tumors are like malignant fortresses, surrounded by a dense matrix of collagen and other tissue that shields them from immune cells and immunotherapies that have been effective in treating other cancers. Employing bacteria to infiltra.....»»
Friday deals: Nano-texture M4 iPad Pro all-time low at $135 off, black Magic Keyboard, M2 iPad Air, accessories, more
Friday has rolled back around again and Amazon has rolled back pricing on the 1TB 13-inch nano-texture glass Apple iPad Pro with M4 to its best price ever alongside ongoing offers on the more affordable models. Those deals now sit alongside the best.....»»
Radioactive drugs strike cancer with precision
Tumor-seeking radiopharmaceuticals promise targeted treatments with fewer side effects. Enlarge / Pharma interest and investment in radiotherapy drugs is heating up. (credit: Knowable Magazine) On a Wednesday morning in.....»»
Wild chimpanzees seek out medicinal plants to treat illness and injuries, study finds
Chimpanzees appear to consume plants with medicinal properties to treat their ailments, according to a study published on June 20 in the open-access journal PLOS ONE by Elodie Freymann from the University of Oxford, UK, and colleagues......»»
A simple, fast, and versatile method for selective bromination of indole alkaloids
The development of drugs through chemical modifications of naturally occurring indole alkaloids has emerged as an attractive research area. However, due to their reactivity, the selective functionalization at the C5 position of the indole ring has be.....»»
Satechi’s new Space Gray Qi2 15W MagSafe Car Charger mount debuts today – Here’s some hands-on impressions
Today, Satechi is its new Qi2 Wireless Car Charger. Following the launch of its Qi2 2-in-1 and , Satechi is now set to bring the new 15W charging standard to your ride with its new magnetic car mount. While it’s not the first car mount of its type.....»»
Hidden partners: Symbiodolus bacteria found in various insect orders
Scientists at the Max Planck Institute for Chemical Ecology report the discovery of at least six orders of endosymbiont Symbiodolus clandestinus, which lives inside insect cells. Using fluorescence in situ hybridization, they showed that Symbiodolus.....»»
Study reveals molecular mechanisms of somatostatin receptor 5 activation by neuropeptides and drugs
Somatostatin receptors (SSTRs) constitute a crucial family of G protein-coupled receptors (GPCRs) that play pivotal roles in regulating hormone secretion and inhibiting tumor growth......»»
Using soil bacteria to help accelerate discovery of new antibiotics
Northeastern researcher Kim Lewis is spearheading an effort to accelerate discovery of new antibiotics as part of a multi-institutional project to tackle the growing problem of antibiotic resistance......»»
Old drugs new tricks—novel approach shows "enormous potential" for rapid antibiotic discovery
An innovative project to re-purpose existing drugs for their potential as antibiotics has uncovered a highly promising candidate with a potent and unique way of killing drug resistant bacteria......»»
Ultrasound beam triggers "nanodroplets" to deliver drugs at exactly the right spot
Conventional drug delivery is often like cracking a nut with a sledgehammer. Whether the drug is swallowed, injected, inhaled, or absorbed through the skin, it ultimately diffuses to most parts of the body, including those where it isn't needed—or.....»»
Investigating nematode-microbe interactions in lab-simulated decomposed beetle environments
Beneath the surface, bacterivorous nematodes are key players in the nutrient cycle, consuming bacteria that decompose organic matter. Traditionally, these nematodes are studied in laboratory environments where isolated bacterial strains are used to m.....»»
Lung-targeting lipid nanoparticles with CRISPR components successfully treat cystic fibrosis mouse models
A team of medical researchers from the University of Texas Southwestern Medical Center, Case Western Reserve University School of Medicine and ReCode Therapeutics has developed a way to send gene-editing tools to the lungs to repair the faulty gene a.....»»
A novel method for measuring nano/microplastic concentrations in soil using spectroscopy
Nano and microplastics are a well-known menace, found practically everywhere in nature, including soil, oceans, drinking water, air, and even the human body. Studies show that soils in particular hold a significant portion of N/MPs......»»
Drugmaker to testify on why weight-loss drugs cost 15x more in the US
Bernie Sanders cancels subpoena vote. Enlarge / Lars Fruergaard Jorgensen, chief executive officer Novo Nordisk A/S, during an interview at the company's headquarters in Bagsvaerd, Denmark, on Monday, June 12, 2023. (credit: Get.....»»
Apple planning redesigned iPhone, MacBook Pro, and Apple Watch that are significantly thinner
Last month, Apple unveiled its thinnest product ever with the new M4 iPad Pro. Measuring in at 5.1mm, the 13-inch M4 iPro Pro is even thinner than the iPod nano. As it turns out, Apple has plans to give the rest of its product lineups a similar tr.....»»
The best e-bike accessories make your ride safer, smoother, and more fun
Getting an e-bike is just the first step for many riders, as there are also a variety of very useful accessories offering protection, utility, and convenience......»»
Some CRISPR screens may be missing cancer drug targets
CRISPR/Cas9 gene editing has made possible a multitude of biomedical experiments, including studies that systematically turn off genes in cancer cells to look for ones that the cancer cells heavily depend on to survive and grow. These genes, or "canc.....»»
To kill the competition, bacteria throw pieces of dead viruses at them
A network of mutual murder ensures that diverse populations of bacteria survive. Enlarge / This is an intact phage. A tailocin looks like one of these with its head cut off. (credit: iLexx) Long before humans became inte.....»»
Improving the ability of phototherapy to stimulate the systemic immune response to cancer
Phototherapy is a safe and effective method for tumor treatment, including photothermal therapy (PTT) and photodynamic therapy (PDT). PTT refers to the use of laser to activate photothermal conversion agents and use high temperature to kill tumor cel.....»»
Upper surface of coastal waters can accumulate bacteria and antibiotics, study finds
Antibiotics in the uppermost water surface, known as the sea surface microlayer, can significantly affect the number of bacteria present and contribute to the adaptation of marine bacteria against widely used antibiotics. In new research presented at.....»»