Decoding the structure of nano "gene ferries" to advance RNA drugs
LMU researchers have investigated how cationic polymers organize on a molecular level when transporting RNA drugs......»»
Scientists synthesize unsymmetrical ureas using non-phosgene method
Unsymmetrical ureas can form multiple stable hydrogen bonds with proteins. Since drugs containing urea functional groups display unique biological activities when interacting with their targets, they play an important role in drug development and med.....»»
Decoding the structure of nano "gene ferries" to advance RNA drugs
LMU researchers have investigated how cationic polymers organize on a molecular level when transporting RNA drugs......»»
Taming big data and particle beams: How researchers are pushing AI to the edge
Every day, researchers at the Department of Energy's SLAC National Accelerator Laboratory tackle some of the biggest questions in science and technology—from laying the foundations for new drugs to developing new battery materials and solving big d.....»»
Capturing complex atoms in optical tweezers
A team led by Francesca Ferlaino has set a new milestone in atomic physics by trapping individual erbium atoms in optical tweezers for the first time. Taking advantage of erbium's complex electronic structure, which opens up new degrees of freedom an.....»»
This week"s space station science: Leads on cancer drugs, satellite sustainability, glass from magnesium silicates
Recent findings from the International Space Station address.....»»
New model can predict marine heat waves, extreme ocean acidity months in advance
In the 21st century, the Earth's oceans are growing warmer and more acidic. This change is happening slowly over the long-term, but it can also cause short-term, local spikes......»»
Josh Brolin says he’ll quit acting if Dune 2 director doesn’t get Oscar nomination
Dune: Part Two star Josh Brolin has made his opinion about next year's Oscar nominations well known in advance......»»
Gene regulation study reports surprising results: Extensive regions of DNA belong to multiple gene switches
Some sequences in the genome cause genes to be switched on or off. Until now, each of these gene switches, or so-called enhancers, was thought to have its own place on the DNA. Different enhancers are therefore separated from each other, even if they.....»»
Accessing the lesser known nucleon: New neutron measurement can help physicists learn about nucleon structure and spin
Protons and neutrons–known collectively as nucleons–are both the building blocks of matter, but one of these particles has received a bit more attention in certain types of nuclear physics experiments......»»
"e-Drive": New gene drive reverses insecticide resistance in pests... then disappears
Insecticides have been used for centuries to counteract widespread pest damage to valuable food crops. Eventually, over time, beetles, moths, flies and other insects develop genetic mutations that render the insecticide chemicals ineffective......»»
Nano-patterned copper oxide sensor provides rapid ultra-low hydrogen detection
Hydrogen is becoming an increasingly popular choice as we shift towards cleaner energy. It can be burned like traditional fuels, producing only water as a byproduct, and can generate electricity when used in fuel cells. However, as hydrogen productio.....»»
Image-processing method enhances visualization of electron microscope images in rubber materials
Researchers at University of Tsukuba have developed a new imaging method that clearly visualizes nanoscale structures within rubber materials. The study is published in the journal ACS Applied Nano Materials......»»
New technique points to unexpected uses for snoRNA across many cell types
Dynamic, reversible modifications of DNA and RNA regulate how genes are expressed and transcribed, which can influence cellular processes, disease development, and overall organismal health. Small nucleolar RNAs (snoRNAs) are a common but overlooked.....»»
Study reveals RNA"s unknown role in DNA damage repair
A multi-institutional team of researchers, led by Georgia Tech's Francesca Storici, has discovered a previously unknown role for RNA. Their insights could lead to improved treatments for diseases like cancer and neurodegenerative disorders while chan.....»»
Origin of life research finds RNA can favor both left- and right-handed proteins
The mystery of why life uses molecules with specific orientations has deepened with a discovery that RNA—a key molecule thought to have potentially held the instructions for life before DNA emerged—can favor making the building blocks of proteins.....»»
Gene expression shifts help explain how a shrew changes brain size to match the seasons
New research shows how the Eurasian common shrew (Sorex araneus) changes its brain and bodily size throughout the year. The study, published online in eLife, reveals how changes in gene expression enable these small mammals to shrink their brain in.....»»
Using gas bubbles to precisely deliver nanomedicines shows promise for lung cancer treatment
The delivery of nanomedicines using gas bubbles has shown itself to be a unique way of transporting cytotoxins to the lungs of cancer patients. The method enables precise and focused treatments, and the local action of the drugs also prevents a range.....»»
Novel nano-vaccine administered as nasal spray found to be effective against all major COVID-19 variants
Researchers at Tel Aviv University have developed an effective, inexpensive, and simple COVID-19 vaccine that can be stored at room temperature and administered as a nasal spray.....»»
Aquaculture researchers decode the genome of the African catfish to advance modern breeding approaches
Scientists at the Research Institute for Farm Animal Biology (FBN) in Dummerstorf have decoded the genome of the African catfish (Clarias gariepinus), in collaboration with international partners......»»
New structure gives insight into mRNA export and cancers, and how viruses hijack the process to infect their host
The central dogma of biology defines the flow of genetic information: It describes how proteins are made from mRNA templates, which are in turn made from DNA. Exporting the mRNA from inside the nucleus to the site of protein translation in the cytopl.....»»