Modified ribosomes could be a possible mechanism of antibiotic resistance
Bacteria modify their ribosomes when exposed to widely used antibiotics, according to research published in Nature Communications. The subtle changes might be enough to alter the binding site of drug targets and constitute a possible new mechanism of.....»»
Parasite genome analysis provides a new approach to predicting malaria drug resistance
Researchers at University of California San Diego analyzed the genomes of hundreds of malaria parasites to determine which genetic variants are most likely to confer drug resistance......»»
Targeting bacterial defense mechanisms for effective antibiotic treatment
In addition to the urgent need for new antibiotics, alternative strategies are required to tackle the problem of antibiotic resistance. Michaela Wenzel, Associate Professor at Chalmers University of Technology, is investigating bacterial defenses aga.....»»
New mechanism in bacterial DNA enzyme opens pathways for antibiotic development
Researchers from Durham University, Jagiellonian University (Poland) and the John Innes Center have achieved a breakthrough in understanding DNA gyrase, a vital bacterial enzyme and key antibiotic target. This enzyme, present in bacteria but absent i.....»»
Cyanobacterial circadian clock uses an AM radio-like mechanism to control cellular processes
Cyanobacteria, an ancient lineage of bacteria that perform photosynthesis, have been found to regulate their genes using the same physics principle used in AM radio transmission......»»
Scientists develop AI tool for personalized phage therapy as a targeted alternative to antibiotics
With the rapid development of antibiotics in the 1930s, phage therapy—using viruses known as bacteriophages or phages to tackle bacterial infections—fell into oblivion. But as the current rise in antibiotic resistance is making it increasingly di.....»»
Sniper Elite: Resistance makes Nazi hunting great again
We jumped into a tense mission from the upcoming Sniper Elite: Resistance to put our Nazi-hunting skills to the test once again......»»
"e-Drive": New gene drive reverses insecticide resistance in pests... then disappears
Insecticides have been used for centuries to counteract widespread pest damage to valuable food crops. Eventually, over time, beetles, moths, flies and other insects develop genetic mutations that render the insecticide chemicals ineffective......»»
3 new PS Plus games you should play this weekend (November 22-24)
Wondering where to start with the new batch of PS Plus Premium and Extra games? Consider Grand Theft Auto V, Resistance: Fall of Man, or Overcooked......»»
Scientists uncover cross-species neural mechanism for early detection of life motion in visual processing
Visual systems of both humans and animals can detect life motion from the environment at the earliest stage of visual processing, research by scientists from the Chinese Academy of Sciences (CAS) uncovered......»»
Low-cost phenotyping system unveils key insights into quantitative disease resistance in wild tomatoes
Quantitative disease resistance (QDR) is a complex but durable form of plant disease resistance that provides partial protection against a broad range of pathogens. Unlike qualitative resistance, driven by major resistance (R) genes, QDR is polygenic.....»»
Study: Why Aztec “death whistles” sound like human screams
The basic mechanism relies on the Venturi effect, producing a unique rough and piercing sound. Archaeologists have discovered numerous ceramic or clay whistles at Aztec sites, dub.....»»
River microbes near wastewater treatment plants express high levels of antibiotic resistance genes, study shows
Rivers and streams serve as critical connectors across vast geographical landscapes, trickling out of tucked-away headwaters and snaking thousands of miles toward oceans and deep seas. These waterways directly impact human and environmental health, a.....»»
Engineered antibiotic D22 shows promise against drug-resistant bacteria
Antibacterial drugs are important for treating infections. But increasingly, bacterial resistance to current drugs—so they don't work well, or even at all—means new ones are urgently needed......»»
Researchers characterize regulating mechanism of orderly zygotic genome activation in early embryos
Early development of an embryo is solely supported by maternally deposited RNAs and proteins until its own genome is activated through a process called zygotic genome activation (ZGA). Recent work by Chinese scientists has revealed a novel molecular.....»»
First successful synthesis of elusive antibiotic compounds since their discovery 50 years ago
Back in 1974, German researchers discovered peculiar chemical compounds, present as red pigments in soil bacteria from a volcanic crater. These biomolecules, which came to be known as naphthocyclinones, are representative of a family of antibiotics w.....»»
Scientists propose drug-free method to combat antibiotic-resistant bacteria
Recent estimates indicate that deadly antibiotic-resistant infections will rapidly escalate over the next quarter century. More than 1 million people died from drug-resistant infections each year from 1990 to 2021, a recent study reported, with new p.....»»
Consciousness Might Hide in Our Brain’s Electric Fields
A mysterious electromagnetic mechanism may be more important than the firing of neurons in our brain to explain our awareness.....»»
The U.S. Must Lead the Global Fight against Superbugs
Antimicrobial resistance could claim 39 million lives by 2050, yet the pipeline for new antibiotics is drying up. U.S. policy makers can help fix it.....»»
Scientists reveal strigolactone perception mechanism and role in tillering responses to nitrogen
"How is plant growth controlled?" and "What is the basis of variation in stress tolerance in plants?" were among the 125 most challenging scientific questions, according to the journal Science in 2016......»»
Sustainable hydrophobic cellulose shows potential for replacing petroleum-related products
A recent study has aimed to create hydrophobic paper by exploiting the mechanical properties and water resistance of cellulose nanofibers, and so produce a sustainable, high-performance material suitable for packaging and biomedical devices. This inv.....»»