Biochemists uncover a new enzyme subclass in antimicrobial lanthipeptide biosynthesis
Biochemists from the National University of Singapore (NUS) have discovered a new subclass of trifunctional enzymes in gram-positive bacteria, which play a critical role in the biosynthesis of an antimicrobial lanthipeptide......»»
Extensive antimicrobial usage sparks warning over increased resistance in locations across Australia
University of Queensland research has found antimicrobial usage is significantly higher in affluent communities in Australia. Samples have been collected from 50 wastewater treatment plants in locations across Australia servicing about 11.3 million p.....»»
Citizen scientist data help uncover the mysteries of a blue low-latitude aurora
Colorful auroras appeared around Japan's Honshu and Hokkaido islands on May 11, 2024, sparked by an intense magnetic storm. Usually, auroras observed at low latitudes appear red due to the emission of oxygen atoms. But on this day, a salmon pink auro.....»»
AI model enables reliable and accurate protein-ligand complex prediction
Understanding protein–ligand interactions is fundamental to molecular biology and biochemistry. These interactions are at the heart of many cellular processes, from enzyme catalysis to signal transduction. The foundational knowledge of protein–li.....»»
Discovery of molecular switch explains how bacteria control their protein biosynthesis through cell metabolism
Protein biosynthesis—the process whereby cells produce protein molecules, which are essential for life and growth—is a highly complex and strictly regulated affair. An interdisciplinary team led by LMU biologist PD Dr. Jürgen Lassak has now disc.....»»
Excavations uncover evidence for the emergence and rejection of the earliest state institutions in Iraq
Excavations at a 4th millennium BCE settlement in Iraqi Kurdistan have revealed new clues about the origins of the world's earliest governing institutions, suggesting they emerged partly from their ability to provide large-scale meals, potentially as.....»»
Enzyme study sheds light on the molecular mechanism behind "sleepiness"
Recent research has observed that chemical modifications called phosphorylation of proteins in brain neurons dynamically regulate sleep and wakefulness. But the protein kinases that suppress sleep and the dephosphorylation enzymes that control sleep.....»»
Scientists uncover new mollusk species co-habiting with an anemone in the North Atlantic abyss
A new species of tusk shell, a burrowing marine mollusk, has been discovered in deep, North Atlantic waters by scientists from the British Antarctic Survey and the Senckenberg Society for Nature Research. The newly discovered mollusk lives in the aby.....»»
Scientists create an enzyme not found in nature for use in efficient synthetic metabolic pathways
A team of researchers led by Tobias Erb at the Max Planck Institute for Terrestrial Microbiology in Marburg has succeeded in developing a new enzyme. The "lactyl-CoA mutase" can efficiently convert a key metabolic compound into valuable products......»»
Resurrecting an ancestral protein as a novel tool to study RNA biology
By deducing the possible ancient forms of a bacterial enzyme, OIST scientists have resurrected one of its ancestral versions, with a comparably higher ability to chemically modify RNA......»»
Biochemists uncover a new enzyme subclass in antimicrobial lanthipeptide biosynthesis
Biochemists from the National University of Singapore (NUS) have discovered a new subclass of trifunctional enzymes in gram-positive bacteria, which play a critical role in the biosynthesis of an antimicrobial lanthipeptide......»»
Biochemical alert system makes quick health and environmental monitoring possible
University of Wisconsin–Madison biochemists have developed a new, efficient method that may give first responders, environmental monitoring groups, or even you, the ability to quickly detect harmful and health-relevant substances in our bodies and.....»»
Study shows hot water reduces E. coli on pecans
Before those sweet and savory pecans make their way into your pecan pie or other holiday treat, they may go through an antimicrobial wash to reduce pathogens. But why would that be needed?.....»»
New mechanism in bacterial DNA enzyme opens pathways for antibiotic development
Researchers from Durham University, Jagiellonian University (Poland) and the John Innes Center have achieved a breakthrough in understanding DNA gyrase, a vital bacterial enzyme and key antibiotic target. This enzyme, present in bacteria but absent i.....»»
Scientists uncover cross-species neural mechanism for early detection of life motion in visual processing
Visual systems of both humans and animals can detect life motion from the environment at the earliest stage of visual processing, research by scientists from the Chinese Academy of Sciences (CAS) uncovered......»»
The U.S. Must Lead the Global Fight against Superbugs
Antimicrobial resistance could claim 39 million lives by 2050, yet the pipeline for new antibiotics is drying up. U.S. policy makers can help fix it.....»»
CMS develops new AI algorithm to detect anomalies at the Large Hadron Collider
In the quest to uncover the fundamental particles and forces of nature, one of the critical challenges facing high-energy experiments at the Large Hadron Collider (LHC) is ensuring the quality of the vast amounts of data collected. To do this, data q.....»»
Mysterious Sydney beach blobs: Scientists uncover their complex composition
A multi-disciplinary team of scientists have made significant progress in understanding the origins of the mysterious black balls washing ashore on Sydney beaches......»»
Mighty radio bursts linked to massive galaxies: New clues about how magnetars form
Since their discovery in 2007, fast radio bursts—extremely energetic pulses of radio-frequency light—have lit up the sky repeatedly, leading astronomers on a chase to uncover their origins. Currently, confirmed fast radio bursts, or FRBs, number.....»»
Enzyme engineering has the potential to drive more sustainable and efficient drug manufacturing
Researchers have found a new way to use biocatalysis to improve the production of critical raw materials required for essential drugs, making the process quicker, more efficient, and environmentally friendly. Biocatalysis is a process that uses enzym.....»»
Researchers uncover focal adhesions as subcellular signaling hubs in PI3K-AKT pathway
The phosphatidylinositol 3-kinase (PI3K)-AKT signaling pathway is one of the most critical and extensively investigated signaling pathways. It is the central regulator of various cellular processes including cell growth, proliferation, metabolism, an.....»»