Cryo-electron microscopy captures structure of a protein pump
Hailey-Hailey disease is a rare, inherited condition characterized by patches of blisters appearing mainly in the skin folds of the arm pits, groin and under the breasts. It is caused by a mutation in the gene that codes for a specific protein involv.....»»
Simulation model shows ribosome tunnel"s impact on protein structures
Researchers at University of Tsukuba have developed a new model that simulates the internal environment of a ribosome—the cellular site of protein synthesis. Using computer simulations, they have analyzed the structures of various proteins within t.....»»
Light microscopy study reveals molecular density changes during mitotic chromosome condensation
A team of scientists studying cell division developed a special light microscopy system and used it to analyze the molecular density of cellular environments. Their results provide a novel insight into mitotic chromosome condensation in living human.....»»
Dual protein analysis approach provides potential way to slow cancer growth
Fighting cancer effectively often involves stopping cancer cells from multiplying, which requires understanding proteins that the cells rely on to survive. Protein profiling plays a critical role in this process by helping researchers identify protei.....»»
Dissecting caspase-2-mediated cell death: From intrinsic PIDDosome activation to chemical modulation
Caspase-2, an initiator caspase, plays a critical role in programmed cell death in response to certain cellular stresses. Its activation is facilitated by the PIDDosome, a multi-protein complex that assembles under conditions of genotoxic stress. Des.....»»
Sound drives "quantum jumps" between electron orbits
Cornell University researchers have demonstrated that acoustic sound waves can be used to control the motion of an electron as it orbits a lattice defect in a diamond, a technique that can potentially improve the sensitivity of quantum sensors and be.....»»
Hubble captures unique ultraviolet view of a spectacular star cluster
Roughly 210,000 light-years away, the Small Magellanic Cloud (SMC) is one of our Milky Way galaxy's closest neighbors. In fact, this small galaxy is one of the Milky Way's "satellite" galaxies, which orbit our home spiral galaxy......»»
The Quantum Mechanics of the Greenhouse Effect
Carbon dioxide’s powerful heat-trapping effect has been traced to a quirk of its quantum structure. The finding may explain climate change better than any computer model......»»
Langbeinites show talents as 3D quantum spin liquids
A 3D quantum spin liquid has been discovered in the vicinity of a member of the langbeinite family. The material's specific crystalline structure and the resulting magnetic interactions induce an unusual behavior that can be traced back to an island.....»»
Ultra-sensitive photothermal microscopy technique detects single nanoparticles as small as 5 nm
The detection of individual particles and molecules has opened new horizons in analytical chemistry, cellular imaging, nanomaterials, and biomedical diagnostics. Traditional single-molecule detection methods rely heavily on fluorescence techniques, w.....»»
New "chiral vortex" of light allows chemists to "see" molecules through the mirror
An entirely new structure of light is helping to measure chirality in molecules more accurately and robustly than ever before, in a major potential step for the pharmaceutical industry......»»
Research unravels dual role of membrane protein in rice ethylene signal transduction
A research team, led by Professor Zhang Jinsong from the Institute of Genetics and Developmental Biology (IGDB) of the Chinese Academy of Sciences, revealed insights into the mechanism by which the membrane protein MHZ3 collaborates with the ethylene.....»»
Single nucleosomes tracked in live cells during cell division using super-resolution microscopy
Individual cells divide through a process called mitosis, during which the cell's copied DNA is separated between two resulting daughter cells. Despite recent advances in cell biology, the mechanism by which DNA condenses during mitosis is still poor.....»»
These colorful diagrams show how air quality has changed in more than 100 countries since 1850
Air pollution is an unseen menace that poses a major threat to human health and the climate. We have created the air quality stripes, a visual tool that captures global air pollution trends, to bring this hidden threat into sharp focus......»»
Vulnerability prioritization is only the beginning
To date, most technology solutions focused on vulnerability management have focused on the prioritization of risks. That usually took the shape of some risk-ranking structure displayed in a table with links out to the CVEs and other advisory or threa.....»»
A small molecular glue that increases P53 level and suppresses tumor growth in vivo
Molecular glues are typically small chemical molecules that act on the interface between the target protein and the degradation machinery to trigger ternary complex formation. Identification of molecular glues is challenging, and there has been a lac.....»»
Developing innovative new display technologies to create ultrahigh-definition screens efficiently
A research team has developed a double-layer dry transfer printing technology that simultaneously transfers light-emitting and electron-transferring layers onto a substrate. This technology is expected to provide a more life-like view in augmented re.....»»
Physicists observe key minuscule molecular interactions in ultra-fast atomic processes
An international team of scientists is the first to report incredibly small time delays in a molecule's electron activity when the particles are exposed to X-rays......»»
App Store VP departing Apple amid broader restructuring
Apple’s App Store vice president is leaving the company in October, according to a new report from Bloomberg. The structure of the App Store team is also being split into two teams, a change implemented by Phil Schiller in response to the ever-.....»»
Survival tactics: AI-driven insights into chromatin changes for winter dormancy in axillary buds
Evolution has enabled plants to survive under adverse conditions. The winter bud of a plant is a crucial structure that establishes adaptability. Depending on environmental and intrinsic conditions, buds can transition between growth and dormancy. Th.....»»
Cryo-ET study elucidates protein folding helpers in their natural environment
Cryo-electron tomography (cryo-ET), can be used to visualize and analyze cellular structures in their natural environment. Researchers at the MPI of Biochemistry in Martinsried and the University Medical Center Göttingen have now used cryo-ET to stu.....»»