Dissecting caspase-2-mediated cell death: From intrinsic PIDDosome activation to chemical modulation
Caspase-2, an initiator caspase, plays a critical role in programmed cell death in response to certain cellular stresses. Its activation is facilitated by the PIDDosome, a multi-protein complex that assembles under conditions of genotoxic stress. Des.....»»
2D graphene spin valve leverages van der Waals magnet proximity for efficient spintronics
Graphene, particularly in its purest form, has long been considered a promising material for developing spintronic devices. These devices leverage the intrinsic angular momentum (i.e., spin), as opposed to the charge, of electrons to transmit and pro.....»»
Death Stranding 2: everything we know so far
The trailer probably raised more questions than answers about Death Stranding 2. We don't know it all, but here's everything we do know about the upcming sequel......»»
Could Ocean Engineering Pull Carbon from the Atmosphere as a Last Resort against Climate Change?
Changing the ocean’s chemical and biological makeup could force it to pull vast amounts of planet-warming carbon from the atmosphere. But is that a line we want to cross?.....»»
Research reveals even single-cell organisms exhibit habituation, a simple form of learning
A dog learns to sit on command, a person hears and eventually tunes out the hum of a washing machine while reading … The capacity to learn and adapt is central to evolution and, indeed, survival......»»
CRISPR-based system labels extracellular vesicles with "barcodes" to better understand cell-to-cell communication
Cell-to-cell communication through nanosized particles, working as messengers and carriers, can now be analyzed in a whole new way, thanks to a new method involving CRISPR gene-editing technology......»»
Reward of $100,000 offered in mysterious death of beloved Mexican gray wolf in Arizona
A beloved Mexican gray wolf, who was known among conservationists as a symbol of hope for the endangered species, was found dead under mysterious circumstances in Arizona......»»
By exerting "crowd control" over mouse cells, scientists make progress towards engineering tissues
Genes aren't the sole driver instructing cells to build multicellular structures, tissues, and organs. In a paper published in Nature Communications, USC Stem Cell scientist Leonardo Morsut and Caltech computational biologist Matt Thomson characteriz.....»»
Statistical approach improves models of atmosphere on early Earth and exoplanets
As energy from the sun reaches Earth, some solar radiation is absorbed by the atmosphere, leading to chemical reactions like the formation of ozone and the breakup of gas molecules. A new approach for modeling these reactions, developed by a team led.....»»
Review makes connections between electron density-based methods
Researchers have published a comprehensive review in Chemical Reviews on electron density-based methods......»»
Fish on film: Uncovering the environmental drivers of black spot syndrome
For many researchers in biology and other natural sciences, dissecting specimens may not be desirable, though it is often necessary. This is because dissection means killing the animal a researcher is trying to study—a big issue, especially if the.....»»
Researchers characterize regulating mechanism of orderly zygotic genome activation in early embryos
Early development of an embryo is solely supported by maternally deposited RNAs and proteins until its own genome is activated through a process called zygotic genome activation (ZGA). Recent work by Chinese scientists has revealed a novel molecular.....»»
A single cell"s siesta: How non-moving single-celled organisms manage to avoid bright light
Too much of a good thing is no good at all. Living organisms enjoy sunlight—in fact, they need it to stay alive—but they tend to avoid light that is too bright. Animals go to their shelter, humans have a siesta, even plants have mechanisms to avo.....»»
First successful synthesis of elusive antibiotic compounds since their discovery 50 years ago
Back in 1974, German researchers discovered peculiar chemical compounds, present as red pigments in soil bacteria from a volcanic crater. These biomolecules, which came to be known as naphthocyclinones, are representative of a family of antibiotics w.....»»
Triazenolysis: A new chemical process to produce raw materials
Researchers at the Schulich Faculty of Chemistry at the Technion have developed a new chemical process to produce raw materials for the manufacture of polymers, pharmaceuticals, and agricultural compounds......»»
Neat, precise and brighter than ever: New technologies improve temporal coherence of XFEL pulses
X-ray free-electron lasers produce pulses of light that are exceptionally bright, making them powerful tools for studying ultrafast chemical reactions, biological processes, or probing the structure of materials at atomic scales......»»
Viscosity of materials key to cell differentiation: New insights could improve design of biomaterials
An IBEC-led study has revealed how mesenchymal stem cells respond to the viscosity of their environment, a key aspect in their differentiation process......»»
Electron imaging reveals the vibrant colors of the outermost electron layer
Surfaces play a key role in numerous chemical reactions, including catalysis and corrosion. Understanding the atomic structure of the surface of a functional material is essential for both engineers and chemists. Researchers at Nagoya University in J.....»»
How marine worms regenerate lost body parts: Return of cells to stem cell-like state could be key
Many living organisms are able to regenerate damaged or lost tissue, but why some are particularly good at this and others are not is not fully understood. Molecular biologists Alexander Stockinger, Leonie Adelmann and Florian Raible from the Max Per.....»»
A clean break: Scientists convert plastics into soaps and detergents
As an undergraduate student at Zhejiang University in eastern China, Greg Liu went with some of his classmates on a university-sponsored trip to tour a host of chemical industries within the area......»»
Selenoproteins open new strategies for treating certain cancers in children
Selenoproteins are crucial for several biological functions, including the breakdown of harmful substances, immune system support, and regulating metabolic processes. However, in specific contexts, these proteins can be misused and shield cancer cell.....»»