Dissecting caspase-2-mediated cell death: From intrinsic PIDDosome activation to chemical modulation
Caspase-2, an initiator caspase, plays a critical role in programmed cell death in response to certain cellular stresses. Its activation is facilitated by the PIDDosome, a multi-protein complex that assembles under conditions of genotoxic stress. Des.....»»
Researchers take "significant leap forward" with quantum simulation of molecular electron transfer
Researchers at Rice University have made a meaningful advance in the simulation of molecular electron transfer—a fundamental process underpinning countless physical, chemical and biological processes. The study, published in Science Advances, detai.....»»
New AA-powered AirTag case promises 10-year lifespan
Aluminum AirTag case replaces coin cell with 2 AA Lithium batteries for extended lifespan. On Wednesday, a startup announced TimeCapsule, a new $20 battery case purported to exten.....»»
AI-driven approach reveals hidden hazards of chemical mixtures in rivers
Artificial intelligence can provide critical insights into how complex mixtures of chemicals in rivers affect aquatic life—paving the way for better environmental protection......»»
Molecular tool demonstrates how bad eggs are identified for destruction by reproductive system
The biological factory that produces reproductive cells has a robust quality control system to identify and eliminate eggs with chromosomal abnormalities. For years, cell biologists have sought to uncover the mechanisms behind this system, relying on.....»»
Cellular RNA plays key role in antiviral defense, study finds
Scientists have uncovered a new role for a cell's own RNA in fending off attacks by RNA viruses. Some of the cell's RNA molecules, researchers found, help regulate antiviral signaling. These signals are part of the intricate coordination of immune re.....»»
Tech used by WWI flying aces inspires new cellular behavior discovery
Researchers at the University of Massachusetts Amherst have designed a new technology that takes inspiration from WWI fighter aircraft machine gun and propeller synchronization to manipulate cell behavior by precisely modulating the pH of the cell's.....»»
Scientists recreate molecular timers to control nanomachine activation rates
Living organisms monitor time—and react to it—in many different ways, from detecting light and sound in microseconds to responding physiologically in pre-programmed ways, via their daily sleep cycle, monthly menstrual cycle, or to changes in the.....»»
Molecular "pinball": Superfast collisions predict supercritical fluid properties
Neither gas nor liquid, supercritical fluids exhibit a unique mashup of the properties of both and arise when fluids are pushed to very high temperatures and pressures. Their properties make them ideal for a wide variety of chemical, pharmaceutical a.....»»
New strategies enhance stability of metal nanoparticles in green hydrogen production
Efficient and durable low-cost catalysts are essential for green hydrogen production and related chemical fuel production, both vital technologies for the transition to renewable energy. Research in this field increasingly focuses on metal exsolution.....»»
Death of a Unicorn trailer: Paul Rudd, Jenna Ortega confront a mythical animal
Paul Rudd and Jenna Ortega play a father and daughter who crash into a mythical creature in the trailer for A24's Death of a Unicorn......»»
New software unlocks secrets of cell signaling, showing realistic simulations
Researchers at University of California San Diego have developed and tested a new software package, called Spatial Modeling Algorithms for Reactions and Transport (SMART), that can realistically simulate cell-signaling networks—the complex systems.....»»
Rocket-inspired reaction yields carbon with record surface area
Using a chemical reaction inspired by rocket fuel ignition, Cornell researchers have engineered a nanoporous carbon with the highest surface area ever reported, a breakthrough that is already proving beneficial for carbon-dioxide capture and energy s.....»»
New method maps hundreds of proteins in cell nuclei simultaneously
Caltech researchers have developed a new method to map the positions of hundreds of DNA-associated proteins within cell nuclei all at the same time. The method, called ChIP–DIP (Chromatin ImmunoPrecipitation Done In Parallel), is a versatile tool f.....»»
Azo-menthol: New molecule can regulate ion channels using light
Located in the cell membrane, TRPM8 ion channels are known as receptors that recognize cold and respond to menthol, the cooling agent in peppermint. In addition, these channels influence pain perception and play a key role in numerous diseases. This.....»»
Nanopore-based "artificial tongue" can determine chemical makeup of alcoholic drinks
A team of chemists and biomedicine specialists at Nanjing University, in China, developed an "artificial tongue" based on biological nanopore technology that can be used to determine the chemical makeup of alcoholic drinks. In their paper published i.....»»
Why Vanuatu should brace for even more aftershocks after this week"s deadly quakes: A seismologist explains
The death toll from Vanuatu's earthquake disaster continues to rise, with international search and rescue operations underway to help people hit by the initial quake and its aftershocks......»»
Building a backbone: Scientists recreate the body"s "GPS system" in the lab
Scientists at the Francis Crick Institute have generated human stem cell models which, for the first time, contain notochord—a tissue in the developing embryo that acts like a navigation system, directing cells where to build the spine and nervous.....»»
NASA missions spot cosmic "wreath" displaying stellar circle of life
Since antiquity, wreaths have symbolized the cycle of life, death, and rebirth. It is fitting then that one of the best places for astronomers to learn more about the stellar lifecycle resembles a giant holiday wreath itself......»»
UK"s inland bathing sites tainted by chemical pollutants and antibiotic resistant genes, researchers find
The U.K.'s rivers are contaminated with a mixture of chemical pollutants and antibiotic resistant genes, which could be causing severe harm to people and aquatic species, according to the findings of a new study......»»
T-Mobile’s long-awaited satellite service is finally ready for testing
T-Mobile is opening the beta registration for its Starlink-driven direct-to-cell satellite service, with plans of a broader launch at some point in 2025......»»