Nucleoside analogs for messenger RNA metabolic labeling and sequencing
High-throughput RNA-sequencing (RNA-seq) is widely used to profile global cellular gene expression and gain insights into cellular biological processes; however, effectively tracking dynamic changes in cellular mRNA expression remains a challenge. Be.....»»
Scientists develop a new method to study gene function in cells and tissue
The Gaublomme lab has developed a new optical pooled screening approach called CRISPRmap, which enables the coupling of optical properties of single cells to targeted genetic perturbations. Optical phenotypes are typically inaccessible for sequencing.....»»
AI decodes microbes" message in milk safety testing approach
By combining the genetic sequencing and analysis of the microbes in a milk sample with artificial intelligence (AI), researchers were able to detect anomalies in milk production, such as contamination or unauthorized additives. The new approach could.....»»
High-resolution structural data shows how a supercomplex links mRNA translation and decay
Messenger RNA (mRNA) serves as a blueprint for proteins. When mRNA is no longer needed, it must be degraded. Director Elena Conti and her team at the Max Planck Institute of Biochemistry in Martinsried near Munich have now been able to show that the.....»»
Psychedelic Mushrooms Are Getting Much, Much Stronger
Cultivators are turning to genetic sequencing and cellular-manipulation techniques to breed highly potent mushrooms—leaving some unprepared psychonauts in distress......»»
Sludge sequencing: High-throughput single-cell method reveals novel species and genetic diversity
Activated sludge is essential for removing contaminants from wastewater, and understanding the diverse microbial communities it harbors has been a significant task. Traditional methods fail to capture the full spectrum of microbial interactions. Due.....»»
Key molecule in wound healing identified through mapping of long non-coding RNA molecules
A new study from Karolinska Institutet and the Chinese Academy of Medical Sciences has identified an RNA molecule that is important for skin wound healing. The research, published in Nature Communications, may have implications for the treatment of h.....»»
LEGO-inspired RNA sensors enable customizable gene control
A research team has developed an RNA-based sensor platform that can regulate gene expression in bacteria. Their findings were recently featured in the journal Advanced Science......»»
Researchers determine how a protein contributes to human immune defense against RNA viruses
An international research team led by Prof. Dr. Janosch Hennig from the University of Bayreuth has discovered how the TRIM25 protein contributes to defense against RNA viruses whose genetic material is contained as ribonucleic acid (RNA)......»»
Q&A: Using a new approach to shine a light on hidden plant microbes
Despite there being more microbes on Earth than stars in our galaxy, only a tiny fraction have been discovered. An approach called metagenomics—a type of DNA sequencing—may help scientists learn more about these elusive organisms, according to Pe.....»»
Exploring the role of hydrogen sulfide in the expression of iron uptake genes in E. coli
Antibiotic resistance and oxidative stress response are important biological mechanisms that help bacteria thrive, especially pathogenic bacteria like Escherichia coli. Hydrogen sulfide (H2S), a chemical messenger molecule, regulates several intracel.....»»
How iron and metabolic constraints can aid gene discovery for photosynthesis and biofuel production
The single-cell green alga Chromochloris zofingiensis is an emerging model organism for photosynthesis and metabolism research. Previous research has shown that with the addition of glucose, Chromochloris zofingiensis shuts off photosynthesis, rerout.....»»
Sloth survival under threat due to climate change, study finds
A new PeerJ study has revealed that sloths, the famously slow-moving creatures of Central and South America, may face existential threats due to climate change. The research, conducted by scientists studying the metabolic response of sloths to rising.....»»
Biologists sequence proteins by pulling them through nanopores
A team of chemical biologists at the University of Washington, working with colleagues at Oxford Nanopore Technologies, has developed a protein sequencing process that involves pulling proteins through nanopores in a lipid membrane. Their paper is pu.....»»
How special is the Milky Way galaxy? Survey team releases new findings
Is our home galaxy, the Milky Way galaxy, a special place? A team of scientists started a journey to answer this question more than a decade ago. Commenced in 2013, the Satellites Around Galactic Analogs (SAGA) Survey studies galaxy systems like the.....»»
Cloud cover and urban structures drastically reduce sunlight in cities
Sunlight plays a crucial role in public health, affecting vitamin D synthesis and psychological well-being. Inadequate exposure to sunlight is associated with various adverse health outcomes, such as cardiovascular diseases, metabolic syndrome, depre.....»»
Blocking someone on X is about to get pointless
So it seems that X is making changes to how blocking someone works, where the blocked user can still view public posts. The post Blocking someone on X is about to get pointless appeared first on Phandroid. Blocking someone in messenger or.....»»
Study explores metabolic disruptions in Artemisia annua mutant strain
Artemisia annua is celebrated for its production of artemisinin, a powerful antimalarial agent. Although its glandular secretory trichomes have been the focus of extensive research, a complete understanding of their metabolic processes remains elusiv.....»»
Google will begin labeling AI-generated images in Search
Google will begin labeling AI-generated search results in the coming months......»»
Google seeks authenticity in the age of AI with new content labeling system
C2PA system aims to give context to search results, but trust problems run deeper than AI tech. Enlarge / Under C2PA, this stock image would be labeled as a real photograph if the camera used to take it, and the toolchain for ret.....»»
The olive tree"s blueprint: Key insights into high-quality oil production
A pivotal study has decoded the genetic basis of olive oil production, revealing a key regulatory mechanism that shapes oil biosynthesis. By mapping the olive tree's genome and metabolic pathways, researchers have identified how MYC2, a critical tran.....»»