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Nucleoside analogs for messenger RNA metabolic labeling and sequencing

High-throughput RNA-sequencing (RNA-seq) is widely used to profile global cellular gene expression and gain insights into cellular biological processes; however, effectively tracking dynamic changes in cellular mRNA expression remains a challenge. Be.....»»

Category: topSource:  physorgJun 21st, 2023

Elevating analysis of genomic data with advanced mathematical techniques

A novel approach to analyzing single-cell RNA sequencing (scRNA-seq) data has been unveiled by NUS researchers. This method promises to enhance both the precision and speed of data interpretation, potentially accelerating progress in numerous areas o.....»»

Category: topSource:  theglobeandmailRelated NewsSep 6th, 2024

Plant thermogenesis has played key role in attracting pollinating insects for at least 200 million years, study suggests

Thermogenesis is a process by which organisms generate internal heat. Although it is usually associated with animals, some plants have also developed this ability. This metabolic process allows certain parts of the plant, such as flowers and inflores.....»»

Category: topSource:  physorgRelated NewsSep 6th, 2024

Dolphin-friendly? New research shows that vague environmental labeling is common on NZ seafood products

Many seafood products sold in New Zealand make environmental claims, but our new research shows most of them are too ambiguous and may serve as greenwashing......»»

Category: topSource:  physorgRelated NewsSep 5th, 2024

Q&A: Scientist discusses the MESSENGER mission to Mercury

Twenty years ago, the MESSENGER mission revolutionized our understanding of Mercury. We sat down with project head and former Carnegie Science director Sean Solomon to talk about how the mission came together and the groundbreaking work it enabled......»»

Category: topSource:  physorgRelated NewsSep 2nd, 2024

Cells use alternative splicing to regulate gene expression, research suggests

Alternative splicing is a genetic process where different segments of genes are removed, and the remaining pieces are joined together during transcription to messenger RNA (mRNA). This mechanism increases the diversity of proteins that can be generat.....»»

Category: topSource:  physorgRelated NewsSep 2nd, 2024

What"s in the foods we eat? Researchers develop a food microbiome database

Microbes are part of the food we eat and can influence our own microbiome, but we know very little about the microbes in our foods. Now, researchers have developed a database of the "food microbiome" by sequencing the metagenomes of 2,533 different f.....»»

Category: topSource:  physorgRelated NewsAug 29th, 2024

Predicting metabolic potential in bacteria from limited genome data

How bacteria eat food, and what kinds of products they can make from that food, is dictated by the metabolic network of enzyme patterns encoded in their genomes. Using computational methods to learn these patterns across a large number of known bacte.....»»

Category: topSource:  physorgRelated NewsAug 8th, 2024

A new model to study regeneration of brown adipose tissues

The prevalence of obesity worldwide has led to an increase in the risk of metabolic diseases and socio-economical burdens. Brown adipose tissue (BAT) has been established as a promising therapeutic target to overcome obesity, type 2 diabetes (T2D) an.....»»

Category: topSource:  physorgRelated NewsJul 30th, 2024

Discovery of a tRNA modification enzyme that also acts on nucleosides

The genetic information on DNA is transcribed into messenger RNA (mRNA) and translated to the amino acid sequence by transfer RNA (tRNA) on the ribosome. Modified nucleosides within RNA are involved in maintaining and regulating the protein synthesis.....»»

Category: topSource:  physorgRelated NewsJul 18th, 2024

Gene silencing tool has a need for speed: Research provides deeper insight into RNAi tool design

RNA interference (RNAi) is a process that many organisms, including humans, use to decrease the activity of target RNAs in cells by triggering their degradation or slicing them in half. If the target is a messenger RNA, the intermediary between gene.....»»

Category: topSource:  physorgRelated NewsJul 18th, 2024

Harmonic Protect helps security teams secure sensitive data

Harmonic Security launched Harmonic Protect which empowers security teams with the tools to protect sensitive data without the headaches of labeling and complex rules. CISOs using Harmonic have coined it “zero-touch data protection” for its uniqu.....»»

Category: securitySource:  netsecurityRelated NewsJul 16th, 2024

Prussian blue analogs unlock affordable, long-lasting lithium-ion batteries

Prussian blue (PB), a well-known pigment used to dye jeans, has been recognized as an emerging material for next-generation batteries. A team of researchers, led by Professor Hyun-Wook Lee in the School of Energy and Chemical Engineering at UNIST has.....»»

Category: topSource:  physorgRelated NewsJul 12th, 2024

"Vaults" within germ cells offer more than safekeeping

Maternal messenger RNAs (mRNAs), located within the cytoplasm of an immature egg, are crucial for jump starting development. Following fertilization, these mRNAs are passed onto the zygote, the first newly formed cell......»»

Category: topSource:  physorgRelated NewsJul 5th, 2024

Study finds ways to enhance transcription factor activity

Transcription factors regulate gene expression by binding specific sequences on DNA, which is an essential step to producing messenger RNAs from protein-coding genes. Denes Hnisz's lab, in collaboration with Martin Vingron's lab at the MPIMG, has dis.....»»

Category: topSource:  physorgRelated NewsJul 5th, 2024

How to delete messages on Facebook Messenger

This tutorial explains how you can delete messages on Facebook Messenger using desktop and smartphone apps. The post How to delete messages on Facebook Messenger appeared first on Phandroid. Facebook Messenger is the most widely used insta.....»»

Category: asiaSource:  phandroidRelated NewsJul 3rd, 2024

Bag to the Future: Sew a Trendy Messenger Bag With Light-Up LED Animations

Build an illuminated, animated, tessellated tote using LED pebble lights and 3D-printed fabric. The post Bag to the Future: Sew a Trendy Messenger Bag With Light-Up LED Animations appeared first on Make: DIY Projects and Ideas for Makers......»»

Category: gadgetSource:  makezineonlineRelated NewsJul 3rd, 2024

Discovering new anti-aging secrets from the world"s longest-living vertebrate

New experimental research shows that muscle metabolic activity may be an important factor in the incredible longevity of the world's oldest living vertebrate species—the Greenland shark. These findings may have applications for conservation of this.....»»

Category: topSource:  physorgRelated NewsJul 3rd, 2024

Advancing poplar genomics: Nearly gap-free genome assembly unveils new insights and applications

A research team has successfully assembled a nearly gap-free, telomere-to-telomere (T2T) genome of Populus ussuriensis, filling gaps present in the P. trichocarpa genome. Leveraging long-read sequencing, the team identified and annotated centromere r.....»»

Category: topSource:  physorgRelated NewsMay 30th, 2024

Microsoft is bringing its Copilot AI to Telegram

It seems that Microsoft is bringing its Copilot AI to more services, and one of those services is the Telegram instant messenger. The post Microsoft is bringing its Copilot AI to Telegram appeared first on Phandroid. Google has been pretty.....»»

Category: asiaSource:  phandroidRelated NewsMay 29th, 2024

ICQ 1996-2024: The first universal messenger had a good run, and is leaving us soon

While you probably haven't thought about it in years, the first mainstream universal messenger app for the Mac and just about every other platform will finally be completely retired in June 2024.Owner Mail.ru's announcement that the messaging program.....»»

Category: appleSource:  appleinsiderRelated NewsMay 25th, 2024