New signaling pathway decoded in the decomposition of damaged lysosomes
Lysosomes are surrounded by a lipid bilayer that separates the acidic environment and the digestive enzymes of the organelle from the cytoplasm. Damage to this layer—lysosomal membrane permeabilization, or LMP for short—can trigger inflammation a.....»»
Buyer of $717K Ford GT files lawsuit saying previous damage not disclosed
A Florida dealer in collectible vehicles and a buyer have accused a Canadian dealership of failing to disclose the 2006 Ford GT Heritage Edition purchased for $716,800 had been seriously damaged in a crash and restored......»»
New signaling pathway decoded in the decomposition of damaged lysosomes
Lysosomes are surrounded by a lipid bilayer that separates the acidic environment and the digestive enzymes of the organelle from the cytoplasm. Damage to this layer—lysosomal membrane permeabilization, or LMP for short—can trigger inflammation a.....»»
Can language models read the genome? This one decoded mRNA to make better vaccines
The same class of artificial intelligence that made headlines coding software and passing the bar exam has learned to read a different kind of text—the genetic code......»»
Security pros are cautiously optimistic about AI
55% of organizations plan to adopt GenAI solutions within this year, signaling a substantial surge in GenAI integration, according to a Cloud Security Alliance and Google Cloud survey. The survey received 2,486 responses from IT and security professi.....»»
New study paves the way for precision drugs to treat blood cancers
The Janus kinase 2 (JAK2) protein mediates signaling from several cytokine receptors in the regulation of hematopoiesis and immune responses. Somatic mutations in human JAK2 lead to constitutive activation and cytokine-independent signaling and under.....»»
Apple supplier TSMC evacuates as earthquake hits Taiwan
A 7.2 magnitude earthquake has hit Taiwan, killing 9, and causing Apple processor manufacturer to temporarily halt production.There are no reports of TSMC facilities being damaged, but some domestic and office blocks were badly hit (Source; Reuters)W.....»»
Apple’s new Beats Solo 4 headphones hit the FCC ahead of launch
In February, images of unreleased Beats Solo 4 headphones were revealed thanks to the iOS 17.4 beta. Now, the Beats Solo 4 have popped up in the FCC’s database, signaling that a launch is imminent. They’ll mark the first update to the Beats Solo.....»»
Setting prairies ablaze in springtime is key to restoring damaged ecosystems, conservationists say
On a recent weekday, short but mighty flames began consuming an expanse of tallgrass in Illinois' Nachusa Grasslands, their advance marked with crackles and pops......»»
Chemists discover a key protein in how lysosomes work
Lysosomes, often reductively referred to as the "garbage disposals" of cells, play a pivotal role in our cells' digestive systems by getting rid of unwanted materials......»»
Researchers reveal evolutionary path of important proteins
New research from the University of Wisconsin–Madison decodes the evolutionary pathway of regulatory proteins, the molecules that help control gene expression......»»
Gene editing technology reveals molecular mechanisms governing diatom population density signals
The intricate dynamics of diatom blooms, influenced by a myriad of external factors and internal signals, continue to fascinate scientists. After recognizing the potential role of density perception and intracellular signaling in dictating these phen.....»»
Scientists identify novel lysosome fission factor
Lysosomes are centers for degradation, recycling, and signaling of cellular materials that are crucial for maintaining cellular homeostasis, development, and aging. To meet various physiological demands, lysosomes continuously remodel their shape and.....»»
Researchers discover new microRNA-regulated pathway to boost iPS cell-derived platelet production
A team of researchers led by Professor Koji Eto (Department of Clinical Application) recently discovered the importance of a microRNA-based regulatory mechanism for enhancing the quality and quantity of platelets generated by iPS cell-derived megakar.....»»
Technician damaged vehicle learning to drive a manual transmission, lawsuit alleges
Two technicians at a Milford, Conn., dealership allegedly damaged a service customer's "dream car" during a joyride where the older one wanted to teach the younger one how to drive a manual transmission vehicle......»»
Core-shell structural units show outstanding toughening effect for ceramics
Toughening has always been an important research direction of structure ceramics. The addition of secondary phases to the ceramic matrix to prepare composite ceramics is an effective toughening pathway in the field of structure ceramics......»»
Hyundai, Kia to recall 147,100 U.S. vehicles over damaged charging unit, NHTSA says
Hyundai will recall 98,878 vehicles, affecting certain Ioniq and Genesis models, while Kia will recall 48,232 vehicles impacting certain EV6 models......»»
Research team establishes synthetic dimension dynamics to manipulate light
In the realm of physics, synthetic dimensions (SDs) have emerged as one of the frontiers of active research, offering a pathway to explore phenomena in higher-dimensional spaces, beyond our conventional 3D geometrical space. The concept has garnered.....»»
Electronic perturbation-promoted interfacial pathway for facile C–H dissociation
Pt-based catalysts have been extensively employed in catalytic propane dehydrogenation (PDH) processes, playing a crucial role in propylene production. However, monometallic Pt catalysts often exhibit inferior propylene selectivity due to the hydroge.....»»
Pesticide-free as a new pathway for agriculture
A new approach is gaining momentum in European agriculture: a "third way" that lies between conventional production and organic farming systems. Here farmers must forego synthetic pesticides only—which is simpler to implement than a switch to organ.....»»
How the Tudors dealt with food waste
More than 10 million tons of food is wasted in the UK each year. Leftovers perish in their plastic Tupperware tombs, supermarket bins heave with damaged but perfectly edible produce, and fields are littered with spoiled harvests. Preventing good food.....»»