Protein signaling pathway provides insights into cell migration and cancer metastasis
The innate immune response is the body's first line of defense against infection, and a successful immune defense takes a village: a combination of physical barriers, chemical attacks, and an army of specialized white blood cells. But maintaining and.....»»
New technique points to unexpected uses for snoRNA across many cell types
Dynamic, reversible modifications of DNA and RNA regulate how genes are expressed and transcribed, which can influence cellular processes, disease development, and overall organismal health. Small nucleolar RNAs (snoRNAs) are a common but overlooked.....»»
tRNAs help some mRNAs get lost in translation
Scientists have discovered that tRNAs can determine how long mRNAs exist in a cell, causing some messages to be stabilized and translated into more protein, while directing others to be degraded and limiting how much protein can be made. They publis.....»»
Study reveals RNA"s unknown role in DNA damage repair
A multi-institutional team of researchers, led by Georgia Tech's Francesca Storici, has discovered a previously unknown role for RNA. Their insights could lead to improved treatments for diseases like cancer and neurodegenerative disorders while chan.....»»
Oldies but goodies: Study shows why elderly animals offer crucial scientific insights
A new study on aging in the animal kingdom has highlighted how urgently Earth's oldest and wisest creatures must be protected, with knowledge and environmental stability lost due to human intervention......»»
Using gas bubbles to precisely deliver nanomedicines shows promise for lung cancer treatment
The delivery of nanomedicines using gas bubbles has shown itself to be a unique way of transporting cytotoxins to the lungs of cancer patients. The method enables precise and focused treatments, and the local action of the drugs also prevents a range.....»»
Confidence drives feedback-seeking behavior: Insights into learning and motivation
A new study from co-lead author Christopher J. Cagna, Ph.D., of the Kessler Foundation examines the determinants of feedback-seeking behavior and their impact on learning. In collaboration with fellow co-lead author, Jamil P. Bhanji, Ph.D., of Rutger.....»»
New structure gives insight into mRNA export and cancers, and how viruses hijack the process to infect their host
The central dogma of biology defines the flow of genetic information: It describes how proteins are made from mRNA templates, which are in turn made from DNA. Exporting the mRNA from inside the nucleus to the site of protein translation in the cytopl.....»»
Spatial interactomics tool maps protein interactions to fight lung cancer
As Ahmet F. Coskun and his team of researchers continue their mission to create a 3D atlas of the human body, mapping cells and tissues, they're making discoveries that could lead to better treatments for the most common type of lung cancer......»»
DNA repair by cooperation between proteins: A look inside the cell"s repair hub
New research from the Kind Group at the Hubrecht Institute sheds light on how cells repair damaged DNA. For the first time, the team has mapped the activity of repair proteins in individual human cells......»»
AI-assisted sorting system automates detection of aluminum-tolerant microbes in acidic soils
Researchers from the Single-Cell Center at the Qingdao Institute of Bioenergy and Bioprocess Technology of the Chinese Academy of Sciences, together with collaborators, developed an artificial intelligence-assisted Raman-activated cell sorting (AI-RA.....»»
CWE top 25 most dangerous software weaknesses
The CWE list of the 25 most dangerous software weaknesses demonstrates the currently most common and impactful software flaws. Identifying the root causes of these vulnerabilities provides insights to shape investments, policies, and practices that p.....»»
Low-cost phenotyping system unveils key insights into quantitative disease resistance in wild tomatoes
Quantitative disease resistance (QDR) is a complex but durable form of plant disease resistance that provides partial protection against a broad range of pathogens. Unlike qualitative resistance, driven by major resistance (R) genes, QDR is polygenic.....»»
Sugar-like nanoparticle covering could boost cancer drug delivery
A spoonful of sugar might actually help medicine go down, according to recent research from the University of Mississippi. And it could reduce the harmful side effects of cancer treatment. Instead of a literal spoonful of sugar, however, the research.....»»
Study reveals how caregiving for loved ones shapes lives of Cleveland"s chronically homeless
Shortly after Jerome's mother died of cancer, he experienced what he described as a "mental breakdown" and, before too long, found himself without a home. Taking care of his mother had drained him—both emotionally and financially......»»
Human Cell Atlas achieves leap in the understanding of the human body
Researchers with the global Human Cell Atlas (HCA) consortium report significant progress in their quest for a better understanding of the cells of the human body in health and disease, with the publication on 20 November of a collection of more than.....»»
Nanofibers made of copper-binding peptides disrupt cancer cells
While toxic in high concentrations, copper is essential to life as a trace element. Many tumors require significantly more copper than healthy cells for growth—a possible new point of attack for cancer treatment......»»
Scientists discover the molecular composition of potentially deadly venomous fish
New research in FEBS Open Bio reveals insights into the venom of two of the most venomous fish species on Earth: the estuarine stonefish (Synanceia horrida) and the reef stonefish (Synanceia verrucosa), which are typically found in the warm and shall.....»»
Algorithm predicts DNA methylation in ancient specimens, providing insight into human evolution
Research published in Nature Ecology & Evolution introduces a novel method for inferring DNA methylation patterns in non-skeletal tissues from ancient specimens, providing new insights into human evolution. As DNA methylation is a key marker of gene.....»»
Ancient DNA sheds light on adaptation of early Europeans at the dawn of the agricultural revolution
Leveraging a unique statistical analysis and applying it to ancient DNA extracted from human skeletal remains, a team of researchers from The University of Texas at Austin and the University of California, Los Angeles has revealed new insights into h.....»»
Research reveals even single-cell organisms exhibit habituation, a simple form of learning
A dog learns to sit on command, a person hears and eventually tunes out the hum of a washing machine while reading … The capacity to learn and adapt is central to evolution and, indeed, survival......»»