New ligand-guided technique enhances drug development
Achieving a level of precision to create complex medicines and materials with extreme accuracy is a longstanding goal of scientists and pharmaceutical companies. If achieved, that precision could lead to the development of more effective drug treatme.....»»
AI model enables reliable and accurate protein-ligand complex prediction
Understanding protein–ligand interactions is fundamental to molecular biology and biochemistry. These interactions are at the heart of many cellular processes, from enzyme catalysis to signal transduction. The foundational knowledge of protein–li.....»»
Russian court sentences kingpin of Hydra drug marketplace to life in prison
The underground marketplace distributed more than a metric ton of narcotics. A Russian court has issued a life sentence to a man found guilty of being the kingpin of a dark web dr.....»»
Peat-bog fungi produce substances that kill tuberculosis-causing bacteria
An analysis of fungi collected from peat bogs has identified several species that produce substances toxic to the bacterium that causes the human disease tuberculosis. The findings suggest that one promising direction for development of better treatm.....»»
Hiring people with disabilities positively influences hotel guest perceptions, finds study
Employing people with disabilities (PWD) in hotels not only enhances social responsibility but also significantly boosts customer intentions to recommend and revisit hotels, according to a new study from the University of Surrey. This pivotal study c.....»»
Poplar tree study discovers a photosynthesis gene that boosts plant height
A team of scientists have identified a gene in poplar trees that enhances photosynthesis and can boost tree height. The study, "An orphan gene BOOSTER enhances photosynthetic efficiency and plant productivity," is published in Developmental Cell, and.....»»
Open-source platform supports large imaging data analysis of single cell responses to manipulation
Modern day drug discovery is shifting from single end point assays to more complex phenotypic assays that query single cell and population responses to chemicals and genetic manipulation......»»
African migrants can drive growth in their home countries, but three barriers stand in the way
The idea that migration is closely linked to development has long been pervasive on the African continent......»»
Mid-Pleistocene climate change may have shaped hominin development and dispersal
A multi-institutional team of evolutionary specialists, climatologists and sociologists has found evidence that climate change during and after the Mid-Pleistocene likely shaped hominin development in parts of what is now Asia......»»
Researchers develop hyper-sampling imaging to deliver ultra-high-resolution images
A research team led by Prof. Zhang Ze from the Aerospace Information Research Institute (AIR) of the Chinese Academy of Sciences has developed a hyper-sampling imaging (HSI) technology that enhances the image quality and resolution of digital imaging.....»»
New laser technique achieves atomic-scale precision on diamond surfaces
Imagine placing an object under a microscope and pressing a button to rearrange the surface atoms with atomic-scale precision. This once sci-fi scenario is now a reality thanks to pioneering research published in Applied Surface Science......»»
Novel organoid mimics all three key cell types of pancreas to offer a view of early fetal development
Researchers from the Organoid group (previously Clevers group) at the Hubrecht Institute have developed a new organoid that mimics the human fetal pancreas, offering a clearer view of its early development. The researchers were able to recreate a com.....»»
AI-enhanced satellite carbon monoxide fast retrieval
A recent study presents a radiative transfer model-driven machine learning technique for retrieving carbon monoxide from the world's first hyperspectral Geostationary Interferometric Infrared Sounder (GIIRS) onboard Fengyun-4B (FY-4B) satellite, prov.....»»
New understanding of a cancer-relevant protein reveals opportunities for drug discovery
A new approach to targeting a protein involved in cell division, which can misfunction in cancer, has revealed new insights into how it functions......»»
Veracode unveils innovations for secure software development
Veracode announced innovations to help developers build secure-by-design software, and security teams reduce risk across their code-to-cloud ecosystem. The latest enhancements in Veracode Fix and Veracode Risk Manager, formerly known as Longbow Secur.....»»
Novel quantum computing algorithm enhances single-cell analysis
A new quantum algorithm developed by University of Georgia statisticians addresses one of the most complex challenges in single-cell analysis, signaling significant impact in both the fields of computational biology and quantum computing......»»
Case study suggests expanded opportunities drew people to mega settlements and spurred innovation 6,000 years ago
The U.N.'s Human Development Index provides new explanations for the success of Europe's first mega settlements......»»
Smart analysis enhances detection of fecal discharges from Danube shipping
Researchers at Karl Landsteiner University of Health Sciences (KL Krems) and ICC Water & Health have developed a new, integrative methodology that enables precise detection of small-scale fecal discharges from inland waterway vessels in flowing water.....»»
Higher-density storage technique could allow diamond disk to store equivalent of 2,000 Blu-ray discs
A team of engineers at the University of Science and Technology of China has developed a new way to code data onto a diamond with higher density than prior methods. In their paper published in the journal Nature Photonics, the group notes that such o.....»»
Modified ribosomes could be a possible mechanism of antibiotic resistance
Bacteria modify their ribosomes when exposed to widely used antibiotics, according to research published in Nature Communications. The subtle changes might be enough to alter the binding site of drug targets and constitute a possible new mechanism of.....»»
Parasite genome analysis provides a new approach to predicting malaria drug resistance
Researchers at University of California San Diego analyzed the genomes of hundreds of malaria parasites to determine which genetic variants are most likely to confer drug resistance......»»