New chemical modification of a natural compound for cancer treatment
Natural compounds often have promising therapeutic potential but using them to treat diseases is hampered due to toxicity or non-desirable effects. Now, a new study led by Gonçalo Bernardes, group leader at the Instituto de Medicina Molecular João.....»»
Shedding light on the mechanism of yeast DNA repair
DNA damage is a cellular phenomenon that introduces structural abnormalities in double-stranded DNA. External factors, such as radiation or chemical agents, as well as internal factors, such as blocked DNA replication, can generate double-strand brea.....»»
Compounds from nucleic acids in food show anticancer effects
When people eat, they ingest the nucleic acids that reside in all living things. The compounds in these acids could inhibit the growth of cancer cells, according to findings published in PLOS ONE by Osaka Metropolitan University Associate Professor A.....»»
Using metal ion-linked nanostructures to improve immune response and boost breast tumor treatment
Immune checkpoint blockade (ICB) is one of the primary methods of tumor immunotherapy. However, clinical data have shown that only a portion of patients respond to ICB treatment. Since the tumor's immune-suppressive environment plays a crucial role i.....»»
Scientists develop new chemical tool for infection research
Researchers from Würzburg and Berlin present a new molecule for visualizing the sphingomyelin metabolism. This offers prospects for innovative therapeutic approaches in infection research. The work is published in the journal Nature Communications......»»
Researchers map 50,000 of DNA"s mysterious "knots" in the human genome
Researchers have mapped 50,000 of DNA's mysterious "knots" in the human genome. The innovative study of DNA's hidden structures may open up new approaches for treatment and diagnosis of diseases, including cancer......»»
Deepfakes: Seeing is no longer believing
The threat of deepfakes lies not in the technology itself, but in people’s natural tendency to trust what they see. As a result, deepfakes don’t need to be highly advanced or convincing to effectively spread misinformation and disinformat.....»»
Climate change feedbacks lead to surge in natural methane emissions
Attempts to cut greenhouse gases made tougher by increased emissions. Enlarge / A view of the Pantanal wetlands in Brazil. New research shows a large chunk of global methane emissions are from rotting vegetation in tropical wetla.....»»
The US Grid Is Adding Batteries at a Much Faster Rate Than Natural Gas
The shift toward renewables is officially in high gear......»»
Researchers develop near-infrared spectroscopy models to analyze corn kernels and biomass
In the agricultural and food industry, determining the chemical composition of raw materials is important for production efficiency, application, and price. Traditional laboratory testing is time-consuming, complicated, and expensive. New research fr.....»»
Study reveals petrogenesis and geodynamic processes of NW Pacific seamount lavas
A study led by Drs. Xun Wei and Xue-Fa Shi from the First Institute of Oceanography, Ministry of Natural Resources, China presents 40Ar-39Ar age, geochemical, and Sr-Nd-Pb-Hf isotopic data of lavas from Hemler, Vlinder, and Il'ichev seamounts in the.....»»
Dual protein analysis approach provides potential way to slow cancer growth
Fighting cancer effectively often involves stopping cancer cells from multiplying, which requires understanding proteins that the cells rely on to survive. Protein profiling plays a critical role in this process by helping researchers identify protei.....»»
Dissecting caspase-2-mediated cell death: From intrinsic PIDDosome activation to chemical modulation
Caspase-2, an initiator caspase, plays a critical role in programmed cell death in response to certain cellular stresses. Its activation is facilitated by the PIDDosome, a multi-protein complex that assembles under conditions of genotoxic stress. Des.....»»
Study reveals bioactive power of a natural spearmint compound against weeds
A recent study reveals the natural compound (-)-carvone in spearmint as a potent and sustainable alternative to chemical herbicides. This research demonstrates how (-)-carvone targets and degrades microtubules in weeds, inducing cell death and inhibi.....»»
US grid adds batteries at 10x the rate of natural gas in first half of 2024
By year's end, 96 percent of the US's grid additions won't add carbon to the atmosphere. (credit: DOE) While solar power is growing at an extremely rapid clip, in absolute terms, the use of natural gas for electricity pr.....»»
A hybrid arrowhead against immune disorders: Bacterially derived natural product inhibits cellular immune response
The so-called immunoproteasome is essential for the cellular immune response. In autoimmune diseases, however, it is overactive. Until now, it has not been possible to selectively inhibit the immunoproteasome without disrupting other cellular mechani.....»»
Manganese nanoparticles can more than double availability of world"s potable water, say scientists
Manganese ferrite nanoparticles could lead to a substantial surge in the availability of drinking water globally when used to modify the filtering sheets currently used in water treatment plants, according to scientists......»»
Ecosystems study finds the higher the environmental stress, the lower the resistance to global change
An international study led by the Institute of Natural Resources and Agrobiology of Seville (IRNAS-CSIC), of the Spanish National Research Council (CISC), has shown that as the number of global change factors increases, terrestrial ecosystems become.....»»
So You’re Underwater: Why Do You See That Circle of Light Above You?
Snell’s window is one of the coolest phenomena in the natural world. You’ve seen it, but do you know what causes it?.....»»
Researchers synthesize molecular aggregates for solar energy applications
No molecule stands alone—they need others, at least when it comes to being able to display useful photophysical, electronic, and chemical properties. When individual molecules combine into an aggregate, or a complex of two or more molecules, they b.....»»
How Twitter—now X—helps with understanding Canadian values and attitudes toward asylum seekers
The treatment of asylum seekers is an important issue for many countries as they grapple with polarized public views on the issue. Some policymakers focus on the need for border security to keep asylum-seekers out and "protect" their nations, while o.....»»