Molecular mechanism of ZDHHC18-mediated palmitoylation of cGAS in innate immunity inhibition
Cyclic GMP-AMP synthase (cGAS), a double-stranded DNA (dsDNA) sensing protein, plays an important role in the strong innate immune response induced by pathogen derived nucleic acids......»»
Next-generation nanocatalysts to revolutionize active electron transfer
Various molecular systems have been developed by researchers for photoinduced (i.e., light-driven) electron transfer, including supramolecules, hybrid materials, and organic polymeric systems. While these systems fulfill the distance criterion requir.....»»
Researchers identify molecular basis for morphological diversity of amniote skull
A research group led by Associate Professor Masayoshi Tokita explored the molecular basis generating the diversity of amniote skull morphology, using embryos of several amniote species as materials......»»
New technique to analyze RNA-RNA interactions in live microbial cells
In a study published in Nature Communications, Prof. Chao Yanjie's group at the Institute of Shanghai Institute of Immunity and Infection of the Chinese Academy of Sciences reported a novel RNA interactome profiling technology (iRIL-seq), which ident.....»»
A mechanism of pressure-induced glass phase transition leading to advanced phase-change memories
When temperature or pressure is applied to a material, its state changes from liquid to solid or remains solid but exhibits structural changes. This change is called a phase transition or change......»»
Using machine learning to optimize volatile fatty acid production in riboflavin-mediated sludge fermentation
Waste activated sludge (WAS) is the most yielding byproduct in municipal wastewater treatment plants (MWTPs), and its disposal poses secondary pollution that severely threatens the environment. Producing volatile fatty acids (VFAs) from WAS is a prom.....»»
Researchers discover a mechanism that controls the identity of stem cells
Researchers at the University of California, Irvine, discovered a mechanism that controls the identity of stem cells. When this mechanism fails, embryonic stem cells revert back in time and become totipotent......»»
Molecular fossils study sheds light on feeding strategy shift in ancient life
Paleontologists are getting a glimpse at life over a billion years in the past based on chemical traces in ancient rocks and the genetics of living animals. Research published in Nature Communications combines geology and genetics, showing how change.....»»
Novel stem cell culture system could lead to future therapies for a variety of disorders
A new study led by UT Southwestern Medical Center molecular biologists presents a novel culture system to grow both embryonic and extraembryonic stem cells, potentially providing important insights into the genesis of congenital malformations and ear.....»»
New modular flow platform for improved SuFEx click chemistry
Researchers at the Flow Chemistry group of the University of Amsterdam's Van 't Hoff Institute for Molecular Sciences have developed a modular flow chemistry platform for a safe and efficient execution of SuFEx (Sulfur(VI) Fluoride Exchange) click ch.....»»
"DNA curtain" technology provides real-time visualization of replication for new scientific insights
A research team, led by Professor Ja Yil Lee in the Department of Biological Sciences at UNIST has made a breakthrough in the field of molecular biology. Their research, published in the journal Nucleic Acids Research, has successfully imaged the rea.....»»
Researchers characterize translation inhibition in CRISPR-Cas antiviral defense system
A recent study in Science uses bioinformatic analysis as well as biochemical and structural studies to characterize a novel family of effector proteins, named Cami1. The research shows that when a virus attacks a bacterium, CRISPR-Cas10 signaling mol.....»»
Could life exist in molecular clouds?
Our search for life beyond Earth is still in its infancy. We're focused on Mars and, to a lesser extent, ocean moons like Jupiter's Europa and Saturn's Enceladus. Should we extend our search to cover more unlikely places like molecular clouds?.....»»
Molecular rulers for high-resolution microscopy
There is good news for researchers working with high-resolution fluorescence microscopy: Biocompatible molecular rulers are available for the first time to calibrate the latest super-resolution microscopy methods......»»
A sun protection mechanism helps plants to survive
Just as people can get sunburned, plants can also suffer from too much sunlight. To stay healthy, they use an internal "sun protection mechanism." Pierrick Bru, a Ph.D. student working with Alizée Malnoë at Umeå Plant Science Centre and Umeå Univ.....»»
A theoretical approach to ferroelectricity in hafnia-related materials
Hafnia ferroelectrics are based on their technical promise and remarkable behaviors, where the peculiarities stem from an active extrinsic mechanism that contributes to their properties from a growing number of new intrinsic features......»»
Laser-induced hydrothermal growth for electrocatalytic applications
In the new study published in the journal International Journal of Extreme Manufacturing on 1 November 2023, researchers from the UK and China reported a novel technique based on a laser-induced hydrothermal reaction (LIHR) mechanism for the growth o.....»»
Fish brains may provide insight into the molecular basis of decision-making
How do animals make decisions when faced with competing demands, and how have decision making processes evolved over time? In a recent publication in Biology Letters, Tina Barbasch, a postdoctoral researcher at the Carl R. Woese Institute for Genomic.....»»
Research reveals clever dosage control mechanism of biallelic genes
Have you ever wondered why we carry two copies of each chromosome in all of our cells? During reproduction, we receive one from each of our parents. This means that we also receive two copies, or alleles, of each gene—one allele per chromosome or p.....»»
Plants found to recruit distinct chemical activities of coumarins under different soil pHs
Plants have two main uptake mechanisms to obtain iron (Fe) from the soils. The type of strategy employed depends on the botanical classification of the plant. In the so-called strategy-I mechanism, plants must first reduce the trivalent iron (Fe3+) i.....»»
Molecular diversity and evolution of far-red light photosynthesis
A collaborative study led by Dr. Christopher Gisriel at Yale University and Dr. Tanai Cardona at Queen Mary University of London, published in Frontiers in Plant Science, offers new insight on the origin and evolution of a unique type of photosynthes.....»»