Molecular mechanism of ZDHHC18-mediated palmitoylation of cGAS in innate immunity inhibition
Cyclic GMP-AMP synthase (cGAS), a double-stranded DNA (dsDNA) sensing protein, plays an important role in the strong innate immune response induced by pathogen derived nucleic acids......»»
Physicists discover molecule-like structure of nuclear ground state
Scientists from the Institute of Modern Physics (IMP) of the Chinese Academy of Sciences (CAS), along with their collaborators, have recently discovered a molecular-type structure in the ground state of atomic nuclei. The study was published in Physi.....»»
Study show extracellular vesicles can also deliver messages from non-human cells
Messenger bubbles produced by human cells can pick up bacterial products and deliver them to other cells, University of Connecticut researchers report in the Nov. 16 issue of Nature Cell Biology. The discovery may explain a key mechanism by which ba.....»»
Q&A: Scientific collaboration paves the way to cleaner technologies for industry
During the nearly five decades of its operation, the European Molecular Biology Laboratory (EMBL) in Hamburg has developed many fruitful collaborations with other scientific institutions located in the Hamburg metropolitan area. One example is the lo.....»»
Unlocking long-term genetic memory: Dormant bacterial spores offer key insights into evolutionary survival strategies
A recent study spearheaded by Prof. Sigal Ben Yehuda and her team at Hebrew University has unveiled a captivating facet of bacterial dormancy. Their research illuminates the mechanism through which dormant bacterial spores uphold and activate an endu.....»»
Researchers identify "unicorn" defense mechanism that protects bacteria from antibiotics
Researchers at McMaster University have discovered unique characteristics of a mechanism used by bacteria to resist an important class of antibiotics. The new research, published in Nature Chemical Biology, shows that resistance to aminoglycoside dru.....»»
Combining extreme-ultraviolet light sources to resolve a quantum mechanical dissociation mechanism in oxygen molecules
For the first time, researchers have succeeded in selectively exciting a molecule using a combination of two extreme-ultraviolet light sources and causing the molecule to dissociate while tracking it over time. This is another step towards specific q.....»»
Unearthing how a carnivorous fungus traps and digests worms
A new analysis sheds light on the molecular processes involved when a carnivorous species of fungus known as Arthrobotrys oligospora senses, traps and consumes a worm. Hung-Che Lin of Academia Sinica in Taipei, Taiwan, and colleagues present these fi.....»»
An effective approach for preparing supramolecular polymers at high concentration
Supramolecular polymers (SPs) are molecular assemblies composed of non-covalently bonded small molecules. They show high recyclability originating from their dynamic nature of monomer binding, which is different from covalent polymers with non-biodeg.....»»
Researchers improve efficacy and efficiency of CRISPR diagnostic technology
Changchun Liu, professor of Biomedical Engineering at UConn Health, has developed a new method that improves existing diagnostic technology for a more rapid, sensitive, and deployable approach to molecular diagnostics......»»
Study sheds new light on mechanism of robust motility of flagellated bacteria
Flagellated bacteria are propelled by the rotation of helical flagellar filaments, each with a flagellar motor at its base. Taking Escherichia coli (E. coli) as an example, each cell has 3–7 flagella whose rotation as a helical bundle enables the c.....»»
Researchers reveal how mycorrhizal species regulate plant-soil carbon in forests
In a study published in Nature Climate Change, researchers led by Prof. Zhu Jiaojun from the Institute of Applied Ecology of the Chinese Academy of Sciences (CAS) have reported a mycorrhizae-mediated trade-off between plant biomass and soil carbon se.....»»
A highly efficient open-shell singlet luminescent diradical with strong magnetoluminescence properties
Open-shell singlet (OS) diradicals are important building blocks for functional molecular materials, with a large number of pioneering works by researchers advancing their development and applications across various fields. Despite this progress, the.....»»
Pushing the boundaries of eco-friendly chemical production with azaarenes
A team of pioneering researchers from the Center for Advanced Bioenergy and Bioproducts Innovation (CABBI) has made a significant leap forward in the complex world of molecular chemistry......»»
Research reveals molecular mechanism of asymmetric calcium-sensitive receptor activation
Calcium-sensing receptors (CaSRs), widely distributed in tissues and organs such as parathyroid glands, intestines, bones and kidneys, sense the concentration of calcium ions in the blood and maintain the calcium balance in the human body. CaSR is so.....»»
Researchers tune the speed of chirality switching
Chiral molecules can have dramatically different functional properties while sharing identical chemical formulae and almost identical structures. The molecular structure of two types of a chiral molecule—so-called enantiomers—are mirror images of.....»»
A novel machine learning model for molecular simulation under an external field
Prof. Jiang Bin's research team at the University of Science and Technology of China (USTC) have developed a universal field-induced recursively embedded atom neural network (FIREANN) model, which can accurately simulate system-field interactions wit.....»»
Judge tosses social platforms’ Section 230 blanket defense in child safety case
Judge: Section 230 doesn’t cover platform design defects allegedly harming kids. Enlarge (credit: ljubaphoto | E+) This week, some of the biggest tech companies found out that Section 230 immunity doesn't shield them f.....»»
Unearthing the terroir effect: Grapevine"s transcriptional response to soil variability
Grapevine is a globally significant fruit crop that exhibits remarkable phenotypic plasticity (PP) due to genotype-per-environment interactions (a concept known as terroir). This adaptability impacts physiological, molecular and biochemical aspects o.....»»
Deciphering grape development: A molecular phenology scale for grapevine berry maturation
Fruit development encompasses a series of physical, biochemical, and physiological shifts influenced by both genetic programming and environmental factors. The growth patterns of fruits like grapes are generally consistent within the same species, bu.....»»
Visualizing "traffic jams" inside living cells
Researchers at the IBS Center for Molecular Spectroscopy and Dynamics (IBS CMSD), led by Director Cho Minhaeng and Professor Hong Seok-Cheol, have unveiled a revolutionary label-free microscopy technique—the Cargo-Localization Interferometric Scatt.....»»