Methylated cyclodextrin effectively prevents the crystallization of supersaturated drugs
In the medicine market, most newly introduced drugs and drug candidates show poor water solubility, which prevents their absorption in the body. This, in turn, limits their therapeutic efficiency. Solubilizing agents such as cyclodextrins (CDs) are c.....»»
NYC"s Eighth Avenue plagued by crime, drugs, violence: "This part is getting bad"
NYC"s Eighth Avenue plagued by crime, drugs, violence: "This part is getting bad".....»»
Man suffers heart problem after rapid weight loss: A GLP-1 cautionary tale
The man developed atrial fibrillation and required hospitalization. Enlarge (credit: Getty | Spauln) The dose makes the medicine—and for many critical prescription drugs, the dose depends on a patient's body weight. Us.....»»
Path to precision: Targeted cancer drugs go from table to trials to bedside
What started in a scientist's dining room is now in tissue-agnostic combo trials. Enlarge (credit: Aurich Lawson) In 1972, Janet Rowley sat at her dining room table and cut tiny chromosomes from photographs she had taken.....»»
Buying shady weight loss drugs online is a bad idea, in case you were wondering
Buying shady weight loss drugs online is a bad idea, in case you were wondering.....»»
New compound found to be effective against "flesh-eating" bacteria
Researchers at Washington University School of Medicine in St. Louis have developed a novel compound that effectively clears bacterial infections in mice, including those that can result in rare but potentially fatal "flesh-eating" illnesses. The com.....»»
Scientists reveal transport mechanism of norepinephrine transporter and binding mode of small molecule and peptide drugs
Noradrenaline (NA) is an important monoamine neurotransmitter in the nervous system. The noradrenaline transporter (NET) located on the presynaptic membrane can transport NA into presynaptic neurons......»»
Electrical impedance tomography plus extracellular voltage activation technique simplifies drug screening
When developing new drugs, understanding their effects on ion channels in the body, such as the human ether-a-go-go-related gene (hERG) ion channel found in neurons and heart muscle cells, is critical. Blocking hERG channels can disrupt a normal hear.....»»
Weight loss drugs like Ozempic can also help people stop smoking
Drugs containing semaglutide, like Ozempic and Wegovy, are intended to help people with diabetes lower their blood glucose levels while also reducing the risk of … The post Weight loss drugs like Ozempic can also help people stop smoking appear.....»»
Mysterious family of malware hid in Google Play for years
Mandrake's ability to go unnoticed was the result of designs not often seen in Android malware. Enlarge A mysterious family of Android malware with a demonstrated history of effectively concealing its myriad spying acti.....»»
Genomewide prediction: A promising approach for improving russet formation in apple breeding programs
A research team has demonstrated that genomewide prediction is a promising approach for targeting russet formation in apple breeding programs. This method effectively predicts the russet trait, which is a complex quantitative trait controlled by many.....»»
Dark and gritty The Penguin trailer debuts at San Diego Comic-Con
"America's a hustle, not that I'm complaining." Colin Farrell stars as Batman villain Oswald Cobblepot in HBO's new series, The Penguin. The merging of Warner Bros. and Discovery effectively put an end to one DC Extended Universe er.....»»
"Russian doll" packaging could boost drug delivery
New technology, which is in the early stages of development, has the potential to significantly enhance the effectiveness and reduce the side effects of drugs and vaccines......»»
Dark matter seen through forest: Study examines matter distribution and supports unknown influence or new particle
The dense peaks in the wavelength distribution graph observed in a Lyman-Alpha forest indeed resemble many small trees. Each of those peaks represents a sudden drop in "light" at a specific and narrow wavelength, effectively mapping the matter that l.....»»
People are overdosing on off-brand weight-loss drugs, FDA warns
Bad math and unclear directions are behind overdoses of up to 20 times the normal amount. Enlarge / Wegovy is an injectable prescription weight-loss medicine that has helped people with obesity. (credit: Getty | Michael Siluk).....»»
Reddit blocking all search engines except Google, as it implements AI paywall
Reddit is now blocking all search engines except Google from indexing its site as it effectively implements a paywall for AI training. Back in February, it was revealed that Google was paying Reddit more than $60M a year to get access to user pos.....»»
The Race for the Next Ozempic
The next wave of obesity drugs could help people lose even more weight—and make some pharma companies a fortune......»»
Scientists hijack natural delivery system to send engineered proteins to target cells
Each cell in the body has its own unique delivery system that scientists are working on harnessing to move revolutionary biological drugs—molecules like proteins, RNA and combinations of the two—to specific diseased parts of the body......»»
HR departments "not trusted" to deal with bullying, finds study
Employees have little trust in Human Resources departments to deal fairly and effectively with workplace bullying, according to a new study published in the Journal of Business Ethics......»»
Strata Identity Continuity prevents mission-critical applications from going offline
Strata Identity announced Identity Continuity, an addition to its Maverics Identity Orchestration platform. This new premium offering ensures business continuity and uninterrupted application access by seamlessly failing over from a primary cloud Ide.....»»
Discovery of daphnane diterpenoids in Daphne pedunculata could lead to new HIV drugs
A research group led by Professor Wei Li of the Department of Pharmacognosy, Faculty of Pharmaceutical Sciences, Toho University, in collaboration with Shenyang Pharmaceutical University in China and Duke University Medical Center in the United State.....»»