Methylated cyclodextrin effectively prevents the crystallization of supersaturated drugs
In the medicine market, most newly introduced drugs and drug candidates show poor water solubility, which prevents their absorption in the body. This, in turn, limits their therapeutic efficiency. Solubilizing agents such as cyclodextrins (CDs) are c.....»»
Simple model system can break down fibrils to investigate drugs for neurodegenerative diseases
The origin of many diseases such as Alzheimer's or Parkinson's can be found at the molecular level in our body, in other words, in proteins. In a healthy system, these proteins are responsible for numerous physiological functions......»»
I effectively previewed Apple’s wall-mounted smart display in 2019, and I think it’ll be a winner
A Bloomberg report yesterday suggested that Apple is working on a wall-mounted smart display panel to act as “a command center for the home” – and that it could launch as early as March of next year. I effectively trialled this concept back.....»»
Zscaler Zero Trust Segmentation prevents lateral movement from ransomware attacks
Zscaler announced a Zero Trust Segmentation solution to provide a more secure, agile and cost-effective means to connect users, devices, and workloads across and within globally distributed branches, factories, campuses, data centers, and public clou.....»»
Monitoring Webb"s mirrors for optimal optics
NASA's James Webb Space Telescope is the largest and most powerful telescope ever launched to space. Its mirror is composed of 18 individual segments that have been aligned so accurately, that they effectively work as a single giant (21.6-foot, or 6......»»
Assessing the efficacy of clinical drugs targeting SARS-CoV-2 main protease
Over the last few years, the SARS-CoV-2 virus, responsible for COVID-19, has undergone significant changes, evolving from the original wild-type strains to the highly transmissible omicron variant......»»
Enzyme engineering has the potential to drive more sustainable and efficient drug manufacturing
Researchers have found a new way to use biocatalysis to improve the production of critical raw materials required for essential drugs, making the process quicker, more efficient, and environmentally friendly. Biocatalysis is a process that uses enzym.....»»
Drugmaker shut down after black schmutz found in injectable weight-loss drug
The warning comes amid a legal war over compounded weight-loss drugs. The Food and Drug Administration is warning consumers not to use any drugs made by a compounding pharmacy in.....»»
New nanocatalyst targets tumors without oxygen
Tumors often contain areas of oxygen-deficient tissue that frequently withstand conventional therapies. This is because the drugs applied in tumors require oxygen to be effective. An international research team has developed a novel mechanism of acti.....»»
Single-molecule tracking technology streamlines drug discovery
New drug discovery is a critical step for improving patients' lives. First, researchers must identify molecules in the body's cells that help drive disease, as these are potential targets for new drugs. The next step is to screen candidate drugs that.....»»
Using machine learning to identify bacterial resistance genes and the drugs to block them
Antibiotic resistance is a growing public health problem around the world. When bacteria like E. coli no longer respond to antibiotics, infections become harder to treat......»»
Why Are Close Elections So Common?
When voters decide between two alternatives, as is effectively the case in the U.S. presidential election, it usually comes down to a neck-and-neck race. Researchers can now explain this mathematically.....»»
Ars Live: What else can GLP-1 drugs do? Join us today for a discussion.
Dr. Daniel Drucker will discuss what's ahead for these blockbuster drugs. News and talk of GLP-1 drugs are everywhere these days—from their smash success in treating Type 2 diab.....»»
Discovery of critical iron-transport protein in malaria parasites could lead to faster-acting medications
Malaria kills over 600,000 people a year, and as the climate warms, the potential range of the disease is growing. While some drugs can effectively prevent and treat malaria, resistance to those drugs is also on the rise......»»
Did Decriminalizing Drugs Such As Fentanyl Cause Opioid Overdose Increase?
Oregon decriminalized hard drugs in 2021 and recriminalized them last month. A new analysis shows the laws likely had little effect on opioid deaths.....»»
The Unsettled Science behind Weight-Loss Drugs for Teens
Wegovy and similar weight-loss medications are becoming widely prescribed for teenagers with obesity, but little is known about their long-term effects.....»»
Ars Live: What else can GLP-1 drugs do? Join us Tuesday for a discussion.
Dr. Daniel Drucker will discuss what ahead for these blockbuster drugs. News and talk of GLP-1 drugs are everywhere these days—from their smash success in treating Type 2 diabet.....»»
A week of Mac announcements – which one are you waiting for? [Poll]
Apple marketing VP Greg Joswiak yesterday revealed that we can expect an exciting week of Mac announcements, starting on Monday morning. The tweet also effectively confirmed that there will be no Mac event, just press releases and small-scale brie.....»»
Drug delivery system overcomes circulatory roadblock that prevents gene therapies from reaching their targets
Exploiting the remarkable capability of viruses to transport gene therapies past what until now has been a circulatory roadblock is at the heart of a University of Alberta-led discovery that promises to re-energize the field of genetic medicine......»»
New chemical treatment reduces number of plant pores that regulate water loss
Researchers from Nagoya University Institute of Transformative Biomolecules (WPI-ITbM) in Japan and their colleagues have identified and derivatized a chemical compound that effectively regulates the density of stomata in model plants. Stomata are cr.....»»
VW China marketing chief Jochen Sengpiehl deported after drugs test
Veteran marketing executive Jochen Sengpiehl's future at VW is uncertain. The automaker has launched an internal investigation after he was deported to Germany from China......»»