Assessing the efficacy of clinical drugs targeting SARS-CoV-2 main protease
Over the last few years, the SARS-CoV-2 virus, responsible for COVID-19, has undergone significant changes, evolving from the original wild-type strains to the highly transmissible omicron variant......»»
A nature conservation paradox: Invasive species are often threatened in their native habitat
Non-native species introduced by humans are among the main causes of global species decline—they were partly responsible for 60% of the species that have become extinct worldwide in recent decades. Non-native mammals in Central Europe include speci.....»»
Analysis provides new insights into the replication of BK polyomavirus, a major cause of kidney transplant failure
BK polyomavirus, or BKPyV, is a major cause of kidney transplant failure. There are no effective drugs to treat BKPyV. Research at the University of Alabama at Birmingham reveals new aspects of BKPyV replication, offering possible drug targets to pro.....»»
Pioneering survey methodology sets new standards for gauging global scientific consensus
An international study led by Professor Peter Vickers of Durham University introduces a novel methodology for rapidly assessing scientific consensus on a global scale......»»
Cold storage and CO₂ extend life of Asian hornet baits for battling invasive species
A research group has found the key to solving one of the main problems in the fight against the Asian hornet: the limited time the baits can be used. This work, published in the Microchemical Journal, established that when stored under cold condition.....»»
A new method for efficient synthesis of anti-cancer drugs
The Wadsworth–Emmons (HWE) reaction is a fundamental reaction in organic chemistry, widely used to create conjugated carbonyl compounds. Conjugated carbonyl compounds are used in many industries for synthesizing perfumes, plastics, and pharmaceutic.....»»
This powerful Oura Ring feature knows if you’re getting sick
Previously part of its beta program, the Symptom Radar feature is now part of the Oura Ring's main app and recognizes early signs of illness......»»
Assessing the sustainability of the Pacific walrus population over the next 75 years
The Pacific walrus, a critically important resource for Alaska and Chukotka Native communities, is subject to rapid habitat loss associated with climate change and increasing human activity in the Arctic. New research published in The Journal of Wild.....»»
Planetary scientists confirm new main-belt comet
A mysterious object discovered in the main asteroid belt in 2021 was determined to be a main-belt comet by Planetary Science Institute Senior Scientist Henry Hsieh, Scott Sheppard of the Carnegie Institution for Science and Audrey Thirouin of Lowell.....»»
Video resource aids vets in assessing cat pain
Cats are masters at masking their pain, a natural instinct to avoid attracting predators. However, this poses a challenge for the veterinarians and care teams who must assess and manage pain in cats......»»
Evidence of human-to-animal SARS-CoV-2 transmission in a Brazilian zoo
Universidade Federal de Minas Gerais-led research at the Belo Horizonte Zoo in Minas Gerais, Brazil, has detected SARS-CoV-2 in multiple captive wild mammals, revealing potential human-to-animal transmission and viral evolution in new hosts......»»
New understanding of a cancer-relevant protein reveals opportunities for drug discovery
A new approach to targeting a protein involved in cell division, which can misfunction in cancer, has revealed new insights into how it functions......»»
Seeing is believing: Leveraging defining morphological features for accurate selection of brain organoids
By combining morphological and single-cell level gene expression analyses, a team of researchers led by Professor Jun Takahashi in the Department of Clinical Application at Kyoto University has established a new non-destructive system to select high-.....»»
$400M seized, 5,500 arrested in global operation targeting cyber fraud
A coordinated international operation involving law enforcement agencies from 40 countries led to the arrest of over 5,500 individuals linked to financial crimes and the confiscation of more than $400 million in virtual assets and government-backed c.....»»
Scientists synthesize unsymmetrical ureas using non-phosgene method
Unsymmetrical ureas can form multiple stable hydrogen bonds with proteins. Since drugs containing urea functional groups display unique biological activities when interacting with their targets, they play an important role in drug development and med.....»»
Decoding the structure of nano "gene ferries" to advance RNA drugs
LMU researchers have investigated how cationic polymers organize on a molecular level when transporting RNA drugs......»»
Taming big data and particle beams: How researchers are pushing AI to the edge
Every day, researchers at the Department of Energy's SLAC National Accelerator Laboratory tackle some of the biggest questions in science and technology—from laying the foundations for new drugs to developing new battery materials and solving big d.....»»
Dynasty Warriors: Origins’ free demo is already winning me over
While I've mostly played Musou spinoff games before, Dynasty Warriors: Origins seems like it will make me a fan of the main series......»»
Aesthetics study examines music"s influence on experience of art
Researchers at the Max Planck Institute for Empirical Aesthetics (MPIEA) in Frankfurt am Main, Germany, have investigated how the combination of music and images influences the aesthetic perception of art, and what role the deliberate correspondence.....»»
Targeting bacterial defense mechanisms for effective antibiotic treatment
In addition to the urgent need for new antibiotics, alternative strategies are required to tackle the problem of antibiotic resistance. Michaela Wenzel, Associate Professor at Chalmers University of Technology, is investigating bacterial defenses aga.....»»
Benchmarking the Continuous Electron Beam Accelerator Facility
It's a paper that's been more than four decades in the making. Published in Physical Review Accelerators and Beams, a study has re-benchmarked the main particle accelerator at the U.S. Department of Energy's Thomas Jefferson National Accelerator Faci.....»»