Enhancing cancer therapy using functionalized photosynthetic bacteria
Targeting malignant tumors with high precision is challenging for biomedical researchers. However, this scenario is likely to witness a paradigm shift in the near future through the use of specially engineered bacteria that can eliminate malignant ce.....»»
Discovery of new bacterial toxins could be key to fighting infections
Researchers have discovered a new group of bacterial toxins that can kill harmful bacteria and fungi, opening the door to potential new treatments for infections. These toxins, found in over 100,000 microbial genomes, can destroy the cells of bacteri.....»»
Unexpected beauty and major antimicrobial power boost as phages form into surprising flower shapes
A group of McMaster researchers who routinely work with bacteriophages—viruses that eat bacteria—had a pleasant and potentially very important surprise while preparing slides to view under a powerful microscope......»»
"Nano-weapon" discovery boosts fight against antibiotic-resistant hospital superbugs
Researchers have discovered how a bacteria found in hospitals uses "nano-weapons" to enable their spread, unlocking new clues in the fight against antibiotic-resistant superbugs......»»
Chemical trick activates antibiotic directly at the pathogen
Colistin is a last-resort antibiotic that is usually only used for severe infections with resistant bacteria. This is due to its severe kidney-damaging side effects, which occur in about 30% of treated patients. A research team at the Helmholtz Cente.....»»
Researchers to explore light and ultrasound therapy for melanoma treatment in pigs
Texas A&M University researchers are collaborating on a new project that studies how ultrasound and light can treat melanomas in pigs......»»
Team develops promising new form of antibiotic that makes bacterial cells self-destruct
To address the global threat of antibiotic resistance, scientists are on the hunt for new ways to sneak past a bacterial cell's defense system. Taking what they learned from a previous study on cancer, researchers from the University of Toronto (U of.....»»
Materials of the future can be extracted from wastewater
A group of researchers is on the way to revolutionizing what biomass from wastewater treatment plants can be used for. Biopolymers from bacteria can be a sustainable alternative to oil-based products, and phosphorus and other minerals can also be har.....»»
Molecular "cut and sew" process could accelerate drug design
A innovative molecular "cut and sew" process by University of Dundee scientists has allowed the design of a research tool that will accelerate drug design for diseases for which no other options exist, including cancer......»»
Single-molecule imaging reveals aberrant DNA-binding dynamics of cancer-linked chromatin remodelers
Biophysical chemists from the National University of Singapore (NUS) have uncovered a previously hidden landscape that governs the intracellular organization and dynamics of SWI/SNF chromatin remodelers, an important class of protein complexes that c.....»»
A method to switch between optical pulling and pushing forces by altering the shape of Fermi arcs in Weyl systems
Optical forces, which act like an invisible "hand," are capable of precisely controlling tiny particles. Optical tweezers, a well-known tool, use this force to capture and manipulate small objects such as cells, bacteria, and viruses. This effect is.....»»
Biofilms study reveals how multiple bacteria species manage to coexist
Biofilms—slimy communities of bacteria—grow on all sorts of surfaces: from glaciers and hot springs to plant roots, your bathtub and fridge, wounds, and medical devices such as catheters. Most biofilms are composed of multiple bacterial species,.....»»
Catching prey with grappling hooks and cannons: The unusual weapons arsenal of a predatory marine bacterium
Countless bacteria call the vastness of the oceans home, and they all face the same problem: the nutrients they need to grow and multiply are scarce and unevenly distributed in the waters around them. In some spots they are present in abundance, but.....»»
Plant fungus provides new drug target for colorectal cancer therapy
Novel chemical compounds from a fungus could provide new perspectives for treating colorectal cancer, one of the most common and deadliest cancers worldwide......»»
Pathogenic system found on Providencia rustigianii has virulence gene akin to Salmonella"s
Salmonella and E. coli are well-known bacteria that cause food poisoning, but less understood are species of Providencia, another causative agent of serious symptoms......»»
Protein signaling pathway provides insights into cell migration and cancer metastasis
The innate immune response is the body's first line of defense against infection, and a successful immune defense takes a village: a combination of physical barriers, chemical attacks, and an army of specialized white blood cells. But maintaining and.....»»
GPT-4-based AI agents show promise for detecting antimicrobial resistance
Researchers at the University of Zurich (UZH) have used artificial intelligence (AI) to help identify antibiotic-resistant bacteria. The team led by Adrian Egli, UZH professor at the Institute of Medical Microbiology, is the first to investigate how.....»»
Mangrove microbes show potential for breaking down plastics
A way to select a suite of mangrove bacteria that can transform plastic has been developed that potentially offers a new strategy in the global toolkit of plastic waste cleanup. Researchers have assessed the impact of polyethylene terephthalate (PET).....»»
Nanoparticle therapy offers new hope for prostate cancer patients
Prostate cancer is the second leading cause of cancer death among American men. A recent study, conducted by researchers from the University of Virginia, Mount Sinai, the University of Michigan, the University of Texas and others, has demonstrated th.....»»
Targeting bacteria: Auxiliary metabolic genes expand understanding of phages and their reprogramming strategy
Viruses that infect bacteria—known as bacteriophages—could be used in a targeted manner to combat bacterial diseases. They also play an important ecological role in global biogeochemical cycles. Recent research by researchers at the University of.....»»
New compounds can activate prodrugs at predetermined locations in the body
Researchers from IOCB Prague have succeeded in preparing compounds capable of activating prodrugs at predetermined locations in the body, enhancing their effectiveness and expediting their action. This will make it possible, for example, to more prec.....»»