Enhancing cancer therapy using functionalized photosynthetic bacteria
Targeting malignant tumors with high precision is challenging for biomedical researchers. However, this scenario is likely to witness a paradigm shift in the near future through the use of specially engineered bacteria that can eliminate malignant ce.....»»
Scientists discover chemical probes for previously "undruggable" cancer target
Hormone-driven cancers, like those of the breast and prostate, often rely on a tricky-to-target protein called Forkhead box protein 1 (FOXA1). FOXA1 mutations can enable these types of cancers to grow and proliferate. Today, FOXA1 is notoriously diff.....»»
Highly-stabilized and selective inhibitor for cancer-causing enzyme developed
A team of researchers from the Hebrew University of Jerusalem, the Weizmann Institute of Science, and the University of Tokyo has made a significant breakthrough in the fight against cancer by developing a highly selective inhibitor for an enzyme cal.....»»
Bacteria discovered in healthy vertebrate brains point to a potential role in brain function
Researchers at the University of New Mexico have identified the presence of bacteria in the healthy brains of fish. Understanding this connection between bacteria and animal brains could have future implications for the study of Alzheimer's disease......»»
New bacteria-based therapy shows promise for fighting cancer
Even as cancer remains a leading cause of death globally, bacteria-based cancer therapy presents an exciting and innovative treatment option. Owing to their ability to penetrate the rigid stromal barrier, bacteria can naturally target solid tumors an.....»»
Calcium transport protein in bacteria offers insights for drug development and food safety
Researchers at Umeå University have revealed details on how bacteria use calcium to regulate vital processes in a way that differs from human cells. This breakthrough is significant in the fight against antibiotic resistance and for increasing safet.....»»
Quantum research unlocks PET scan potential in disease detection
New research in quantum entanglement could vastly improve disease detection, such as for cancer and Alzheimer's disease......»»
Novel nanoparticle therapy targets fat absorption to combat obesity
Researchers have unveiled a novel approach to tackle obesity by targeting fat absorption in the small intestine. The cutting-edge nanoparticle system, engineered to deliver therapeutic molecules directly to the digestive tract, has shown significant.....»»
Why a diabetes drug fell short of anticancer hopes
Studies suggested it could treat cancer, but the clinical trials were a bust. Pamela Goodwin has received hundreds of emails from patients asking if they should take a cheap, read.....»»
Mars analog stations investigate lichen biodiversity during simulated missions
Once you know where to look for them, lichens are everywhere. These composite organisms—fungal and photosynthetic partners joined into a greater whole—can survive on a vast array of surfaces, from rocks and trees to bare ground and buildings. The.....»»
Scientists discover how innate immunity envelops bacteria
The protein GBP1 is a vital component of our body's natural defense against pathogens. This substance fights against bacteria and parasites by enveloping them in a protein coat, but how the substance manages to do this has remained unknown until now......»»
Targeting "selfish" bacteria could optimize inhibitors that fight antibiotic resistance
As strains of pathogens resistant to frontline antibiotics become more common worldwide, clinicians are more often turning to combination treatments that degrade this resistance as a first treatment option......»»
Barnacle-inspired polymers could present new way to design antibiotics, researchers say
Scientific literature has shown that barnacles that cling to rocks at the seashore use naturally occurring chemicals to clear rock surfaces of bacteria in preparation for laying down their sticky "glue." Since bioengineering professor Abraham Joy's l.....»»
Detailed images of key protein complexes provide new insights into bacterial photosynthesis
Researchers at the University of Liverpool and collaborators have arrived at a new understanding of bacterial photosynthesis. Using novel techniques, investigators have unveiled intricate detailed images of the key photosynthetic protein complexes of.....»»
How Chlamydia pneumoniae bacteria use molecular mimicry to manipulate the host cell
Bacteria that cause diseases, so-called pathogens, develop various strategies to exploit human cells as hosts to their own advantage. A team of biologists from Heinrich Heine University Düsseldorf (HHU), together with medical professionals and exper.....»»
Nanopore technique shows transport mechanism of chaperone proteins at the single-molecule level
Proteins control most of the body's functions, and their malfunction can have severe consequences, such as neurodegenerative diseases or cancer. Therefore, cells have mechanisms in place to control protein quality......»»
Research team develops metallodrug-antibiotic combination strategy to combat superbugs
Antimicrobial resistance (AMR) bacterial infections have become a serious problem threatening human health worldwide. The overuse of antibiotics has promoted drug-resistant mutations in bacteria, causing almost all clinically used antibiotics to deve.....»»
Alcohol Plays a Major Role in New Cancer Cases
A new report estimates that 40 percent of all cancer cases are associated with factors we can change—alcohol consumption being a prominent one......»»
Cancer, cardiovascular drugs tipped for Nobel as prize week opens
Cancer research or drugs treating cardiovascular illnesses could win a Nobel Prize on Monday when a week of laureate announcements kicks off, bringing a ray of optimism to a world beset by crises......»»
Trees" own beneficial microbiome could lead to discovery of new treatments to fight citrus greening disease
Citrus trees showing natural tolerance to citrus greening disease host bacteria that produce novel antimicrobials that can be used to fight off the disease, our recent study shows. We found the trees at an organic farm in Clermont, Florida......»»
Phage cocktail shows promise against drug-resistant bacteria
Researchers have a new battle tactic to fight drug-resistant bacterial infections. Their strategy involves using collections of bacteriophages, viruses that naturally attack bacteria. In a new study, researchers at the University of Chicago Pritzker.....»»