Downstream RNA hairpins found orchestrating mRNA translation
Research led by Duke University, Durham, has discovered a situation-dependent traffic jam in mRNA translation caused by RNA hairpins leading to higher translation of upstream start codons (uAUGs)......»»
New mRNA technology turns cells into long-lasting drug factories
A team of researchers has established a ribonucleic acid (RNA)-based method that drives cells in the body to produce therapeutic proteins and secrete them into the bloodstream. The approach could potentially extend the lifespan of drugs in the body,.....»»
US prepares for bird flu pandemic with $176M Moderna vaccine deal
Phase 3 trial is expected to begin next year. Enlarge (credit: Getty | Justin Sullivan) The US government will pay Moderna $176 million to develop an mRNA vaccine against a pandemic influenza—an award given as the high.....»»
Mussels downstream of wastewater treatment plant contain radium, study reports
Burrowed into streambeds and rarely moving for their decades-long lifespans, freshwater mussels are biomonitors, meaning they indicate how clean their environment is, according to Penn State researchers. As the bivalves feed on organic matter and fil.....»»
Scientists are testing mRNA vaccines to protect cows and people against bird flu
The bird flu outbreak in U.S. dairy cows is prompting development of new, next-generation mRNA vaccines—akin to COVID-19 shots—that are being tested in both animals and people......»»
As bird flu spreads in cows, US close to funding Moderna’s mRNA H5 vaccine
If trials are successful, US government likely to buy doses for vaccine stockpile. Enlarge (credit: Digicom Photo/Science Photo Library via Getty) The US government is nearing an agreement to bankroll a late-stage trial.....»»
Researchers investigate changes in surface heat fluxes on sensitive areas for the slopes of Mt Everest
Under the background of global warming, the Mount Everest region has experienced evident climate changes. Glaciers and snow have been rapidly retreating in this region. These changes increase the rate of warming and water scarcity in downstream areas.....»»
Real-time video translation comes to Microsoft Edge
AT Build 2024, Microsoft announced an update to Edge that will grant it the power to translate videos to different languages in real time......»»
Lipid nanoparticle-mRNA regimen reverses inflammation and aids recovery from diabetic wounds in mice
Researchers at the Icahn School of Medicine at Mount Sinai have designed a regenerative medicine therapy to speed up diabetic wound repair. Using tiny fat particles loaded with genetic instructions to calm down inflammation, the treatment was shown t.....»»
Microsoft says “Prism” translation layer does for Arm PCs what Rosetta did for Macs
Prism layer is one of several under-the-hood overhauls in Windows 11 24H2. Enlarge / A PC running Windows 11. (credit: Microsoft) Microsoft is going all-in on Arm-powered Windows PCs today with the introduction of a Snap.....»»
Genes spatially organize for efficient mRNA splicing, study shows
The nucleus of each of your cells contains all the genetic information (the genome) necessary to build every type of cell and protein in your entire body. Like a complex library in a tiny space 50 times smaller than the width of a human hair, genes a.....»»
Decoding development: mRNA"s role in embryo formation
A new study at Hebrew University reveals insights into mRNA regulation during embryonic development. The study sheds light on the intricate process of mRNA regulation during embryonic development, providing novel insights into how pluripotent cells a.....»»
Oil palm plantations are driving massive downstream impact to watershed
The global demand for palm oil—the most widely consumed vegetable oil on the planet, in everything from instant noodles to lipstick—is driving worldwide tropical deforestation. While many studies have shown the loss of biodiversity when rainfores.....»»
Developing a tech platform for fast, robust series production of nanoparticles
Nucleic acid-based medications such as mRNA vaccines offer tremendous potential for medicine and are opening up new therapeutic approaches. These active ingredients must be enclosed inside nanoparticles to ensure that they get to where they are neede.....»»
GenAI can enhance security awareness training
One of the biggest concerns over generative AI is its ability to manipulate us, which makes it ideal for orchestrating social engineering attacks. From mining someone’s digital footprint to crafting highly convincing spear phishing emails, to voice.....»»
A new coating method in mRNA engineering points the way to advanced therapies
Medicine can help to treat certain illnesses; for example, antibiotics can help overcome infections, but a new, promising field of medicine involves providing our body with the "blueprint" for how to defeat illnesses on its own......»»
Can language models read the genome? This one decoded mRNA to make better vaccines
The same class of artificial intelligence that made headlines coding software and passing the bar exam has learned to read a different kind of text—the genetic code......»»
Must mRNA be cloaked in a lipid coat to serve as a vaccine?
The Uchida Laboratory of Innovation Center of NanoMedicine has demonstrated that intradermal administration of mRNA alone (naked mRNA) without protection by nanoparticles induced robust vaccination against SARS CoV-2, a virus causing COVID-19, in mic.....»»
Chemists develop method to confirm mRNA vaccine stability
University at Albany researchers at the RNA Institute have developed a new method to test COVID-19 vaccine integrity that could allow anyone with basic skills in vaccine handling to detect expired vaccines quickly and effectively, without specialized.....»»
Scientists identify first negative regulator of NOX4 translation
Nicotinamide adenine dinucleotide phosphate oxidase 4 (NADPH oxidase 4, NOX4) is an important member of the NADPH oxidase family that is primarily responsible for the production of H2O2. The regulation of NOX4 activity is predominantly through protei.....»»
Can mRNA vaccines help boost livestock production?
University of Queensland researchers say mRNA vaccine technology could play an important role in boosting livestock production to meet global food demands......»»