Downstream RNA hairpins found orchestrating mRNA translation
Research led by Duke University, Durham, has discovered a situation-dependent traffic jam in mRNA translation caused by RNA hairpins leading to higher translation of upstream start codons (uAUGs)......»»
Cloud as stumbling block for the propagation of the Southern Annular Mode
The Southern Annular Mode (SAM), with an iconic dipolar zonal wind pattern centered around the axis of the storm track, is the most dominant mode of variability orchestrating the weather and wind from the subtropics to the poles. Its origin, maintena.....»»
What killed fish for miles in the South River? Atlanta officials are investigating
Officials are investigating a pollution incident that occurred earlier this month a few miles south of downtown Atlanta, which local water advocates say sent toxins into a tributary of the South River and killed fish for miles downstream......»»
Orchestrating a swarm of robots for exploration of canyon on Mars
An enormous canyon stretches across Mars: Valles Marineris is 3,000 kilometers long, 600 kilometers wide and on average 8 kilometers deep. Its Latin name goes back to the Mars orbiter Mariner, which discovered the valley in the early 1970s......»»
Glitch in protein synthesis could affect tumor growth
During protein synthesis, or translation, genetic information transcribed in the cell's mRNA directs the stringing together of amino acids—the building blocks of proteins. As the translation machinery carouses along the string of nucleotides that m.....»»
Researchers examine how drought and water volume affect nutrients in Apalachicola river
Near the Florida-Georgia border, the Chattahoochee and Flint rivers meet and become the Apalachicola River, which carries freshwater and nutrients downstream to the Apalachicola Bay......»»
New mRNA and gene editing tools offer hope for dengue virus treatment
Dengue virus, a painful and sometimes fatal mosquito-borne infection well known in tropical countries, is surging rapidly across the planet. Now, 4 billion people live in places at risk for the disease, like the southeastern United States, which does.....»»
Moderna mRNA mpox vaccine shows promise in animal study
An experimental Moderna mRNA vaccine for mpox has demonstrated greater effectiveness than current shots in reducing disease symptoms and duration, according to an animal study published in the journal Cell on Wednesday......»»
India"s new mega-dam will roil lives downstream with wild swings in water flow every day
"Hey Rupam, open the door. Take this fish," a woman yelled from outside. I was sitting in the kitchen at my friend Rupam's house in rural northeast India. It was the heart of monsoon season, and rain had been falling since morning. The woman must hav.....»»
Cells use alternative splicing to regulate gene expression, research suggests
Alternative splicing is a genetic process where different segments of genes are removed, and the remaining pieces are joined together during transcription to messenger RNA (mRNA). This mechanism increases the diversity of proteins that can be generat.....»»
Sinon: Open-source automatic generative burn-in for Windows deception hosts
Sinon is an open-source, modular tool for the automatic burn-in of Windows-based deception hosts. It aims to reduce the difficulty of orchestrating deception hosts at scale while enabling diversity and randomness through generative capabilities. Sino.....»»
The Next Frontier for mRNA Could Be Healing Damaged Organs
Researchers are testing the use of mRNA to get damaged livers to repair themselves, in a move that could one day lessen the need for organ transplants......»»
FDA green-lights fall COVID-19 boosters
Updated mRNA vaccines from Pfizer and Moderna are ready to roll. Enlarge (credit: Getty Images) As the COVID-19 case count continues to tick upward, the US Food and Drug Administration has approved an updated vaccine for.....»»
Lipid nanoparticle mRNA therapy improves survival in mouse models of maple syrup urine disease
Researchers from the University of Pennsylvania, Perelman School of Medicine, Gene Therapy Program, and Moderna, have shown that repeated administration of lipid nanoparticle-encapsulated mRNA therapy significantly extended survival and reduced serum.....»»
"Mercury bomb" threatens millions as Arctic temperatures rise, study warns
The Yukon River flows west across Alaska toward the Bering Sea, eroding Arctic permafrost along its banks and transporting sediment downstream. Within that sediment lurks a toxic stowaway: mercury......»»
Light-responsive gene regulation at the mRNA level
Researchers at the University of Bayreuth have established a new optogenetic approach that can control the bacterial production of proteins at the mRNA level using blue light. The new system gates the activation of the genetic substance particularly.....»»
Discovery of a tRNA modification enzyme that also acts on nucleosides
The genetic information on DNA is transcribed into messenger RNA (mRNA) and translated to the amino acid sequence by transfer RNA (tRNA) on the ribosome. Modified nucleosides within RNA are involved in maintaining and regulating the protein synthesis.....»»
Study highlights potential for genetic manipulation in cucumber breeding
The CLAVATA (CLV) signaling pathway is crucial for controlling flower and fruit development by regulating the shoot apical meristem (SAM) size. Despite its significance, the downstream signaling components in crops remain largely unknown. Understandi.....»»
Restoring eroded peatlands could reduce flood risk for communities downstream, say UK researchers
Scientists from The University of Manchester, The University of Aberdeen and Newcastle University have found that the restoration of upland peatlands is a highly effective strategy for reducing downstream flooding......»»
Team pioneers a "one-pot platform" to promptly produce mRNA delivery particles
Imagine a scenario where a skilled hacker must upload critical software to update a central server and thwart a potentially lethal virus from wreaking havoc across a vast computer network. The programmer, armed with the lifesaving code, must navigate.....»»
US Government Awards Moderna $176 Million for mRNA Bird Flu Vaccine
As fears of a pandemic mount, the biotech company’s mRNA vaccine trial is set to release Phase 1/2 results later this year, with a larger Phase 3 trial expected to begin in 2025......»»