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Must mRNA be cloaked in a lipid coat to serve as a vaccine?

The Uchida Laboratory of Innovation Center of NanoMedicine has demonstrated that intradermal administration of mRNA alone (naked mRNA) without protection by nanoparticles induced robust vaccination against SARS CoV-2, a virus causing COVID-19, in mic.....»»

Category: topSource:  theglobeandmailApr 3rd, 2024

A new coating method in mRNA engineering points the way to advanced therapies

Medicine can help to treat certain illnesses; for example, antibiotics can help overcome infections, but a new, promising field of medicine involves providing our body with the "blueprint" for how to defeat illnesses on its own......»»

Category: topSource:  physorgRelated NewsApr 10th, 2024

SD Card Data Recovery Made Simple: Your Expert Guide with Wondershare Recoverit

In today’s digital age, SD cards serve as an essential medium for storing and transferring data, from work documents to personal memories. Yet, a single mishap can lead to significant data loss, causing immense frustration. If you encounter thi.....»»

Category: asiaSource:  phandroidRelated NewsApr 10th, 2024

Republicans who support childhood vaccine mandates often stay silent, research suggests

Most Republican voters support childhood vaccine mandates, yet may be discouraged from publicly expressing these views, a new study suggests......»»

Category: topSource:  physorgRelated NewsApr 9th, 2024

New signaling pathway decoded in the decomposition of damaged lysosomes

Lysosomes are surrounded by a lipid bilayer that separates the acidic environment and the digestive enzymes of the organelle from the cytoplasm. Damage to this layer—lysosomal membrane permeabilization, or LMP for short—can trigger inflammation a.....»»

Category: topSource:  pcmagRelated NewsApr 8th, 2024

Can language models read the genome? This one decoded mRNA to make better vaccines

The same class of artificial intelligence that made headlines coding software and passing the bar exam has learned to read a different kind of text—the genetic code......»»

Category: topSource:  physorgRelated NewsApr 6th, 2024

Innovative sensing platform unlocks ultrahigh sensitivity in conventional sensors

Optical sensors serve as the backbone of numerous scientific and technological endeavors, from detecting gravitational waves to imaging biological tissues for medical diagnostics. These sensors use light to detect changes in the properties of the env.....»»

Category: topSource:  physorgRelated NewsApr 6th, 2024

Must mRNA be cloaked in a lipid coat to serve as a vaccine?

The Uchida Laboratory of Innovation Center of NanoMedicine has demonstrated that intradermal administration of mRNA alone (naked mRNA) without protection by nanoparticles induced robust vaccination against SARS CoV-2, a virus causing COVID-19, in mic.....»»

Category: topSource:  theglobeandmailRelated NewsApr 3rd, 2024

How to set up the Blink Mini 2 as a chime

The Blink Mini 2 can serve as a chime for your Blink Video Doorbell. Here's a look at how to sync the two together and get them working in just a few minutes......»»

Category: topSource:  digitaltrendsRelated NewsApr 2nd, 2024

Saharan dust smothers Switzerland, southeast France

An exceptionally rare haze of Saharan dust cloaked Switzerland and southeastern France on Saturday, sparking health warnings as a yellow hue tinged the sky......»»

Category: topSource:  physorgRelated NewsMar 31st, 2024

Tuberculosis vaccine may enable elimination of the disease in cattle by reducing its spread

Vaccination not only reduces the severity of TB in infected cattle, but reduces its spread in dairy herds by 89%, research finds. The research, led by the University of Cambridge and Penn State University, improves prospects for the elimination and c.....»»

Category: topSource:  physorgRelated NewsMar 28th, 2024

Chemists develop method to confirm mRNA vaccine stability

University at Albany researchers at the RNA Institute have developed a new method to test COVID-19 vaccine integrity that could allow anyone with basic skills in vaccine handling to detect expired vaccines quickly and effectively, without specialized.....»»

Category: topSource:  physorgRelated NewsMar 28th, 2024

Artificial reef designed by engineers could protect marine life, reduce storm damage

The beautiful, gnarled, nooked-and-crannied reefs that surround tropical islands serve as a marine refuge and natural buffer against stormy seas. But as the effects of climate change bleach and break down coral reefs around the world, and extreme wea.....»»

Category: topSource:  physorgRelated NewsMar 26th, 2024

Can mRNA vaccines help boost livestock production?

University of Queensland researchers say mRNA vaccine technology could play an important role in boosting livestock production to meet global food demands......»»

Category: topSource:  theglobeandmailRelated NewsMar 22nd, 2024

Decommissioned offshore structures could offer only limited ecological benefits, analysis of studies suggests

Decommissioned offshore structures offer limited long-term ecological benefits if they are simply left in the ocean to serve as artificial reefs, a new study suggests......»»

Category: topSource:  physorgRelated NewsMar 22nd, 2024

Messenger RNAs with multiple "tails" could lead to more effective therapeutics, say researchers

Messenger RNA (mRNA) made its big leap into the public limelight during the pandemic, thanks to its cornerstone role in several COVID-19 vaccines. But mRNAs, which are genetic sequences that instruct the body to produce proteins, are also being devel.....»»

Category: topSource:  physorgRelated NewsMar 22nd, 2024

New student advisor is an AI bot that designs academic plans, suggests books

The Los Angeles school district on Wednesday unveiled a much-awaited AI tool named "Ed" to serve as a new student adviser, programmed to tell its young users and their parents about grades, tests results and attendance—while giving out assignments,.....»»

Category: topSource:  physorgRelated NewsMar 21st, 2024

Salt marshes put to the test in wave flume

Can salt marshes serve as a natural solution for flood protection? Researchers of the project "Living Dikes" transported 62 big blocks of salt marshes, containing soil and vegetation, from the coast of Friesland to the Delta Flume at Deltares. After.....»»

Category: topSource:  physorgRelated NewsMar 21st, 2024

Research seeks to develop mRNA lipid nanoparticles for next-generation oral cancer tumor suppressor therapy

A study aiming to develop a lipid nanoparticles (LNP) platform for treating oral squamous cell carcinoma (OSCC) utilizing p53 mRNA was presented at the 102nd General Session of the IADR, which was held in conjunction with the 53rd Annual Meeting of t.....»»

Category: topSource:  physorgRelated NewsMar 19th, 2024

US government agencies demand fixable ice cream machines

McFlurries are a notable part of petition for commercial and industrial repairs. Enlarge / Taylor's C709 Soft Serve Freezer isn't so much mechanically complicated as it is a software and diagnostic trap for anyone without authori.....»»

Category: topSource:  arstechnicaRelated NewsMar 15th, 2024

Danish chef to launch gourmet dining to stratosphere

Danish chef Rasmus Munk wants to take high-end cuisine to the edge of space, with plans to serve up a stratospheric dining experience in 2025, his restaurant said Thursday......»»

Category: topSource:  physorgRelated NewsMar 14th, 2024