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Must mRNA be cloaked in a lipid coat to serve as a vaccine?

The Uchida Laboratory of Innovation Center of NanoMedicine has demonstrated that intradermal administration of mRNA alone (naked mRNA) without protection by nanoparticles induced robust vaccination against SARS CoV-2, a virus causing COVID-19, in mic.....»»

Category: topSource:  theglobeandmailApr 3rd, 2024

Windrose plans truck assembly in U.S. in rare move by a Chinese EV maker

Windrose's U.S. factory, to be built in Georgia, will piece together chassis and other vehicle parts manufactured in China to serve U.S. customers, the company's CEO says......»»

Category: topSource:  autonewsRelated NewsJul 23rd, 2024

"Diagnose, treat and prevent:" Scientists develop test and vaccine for common veterinary infection

Eight years after the market release of VANGUARD crLyme, a first-of-its-kind vaccine designed to prevent Lyme disease in dogs, the Marconi laboratory in the Department of Microbiology and Immunology of the Virginia Commonwealth University School of M.....»»

Category: topSource:  physorgRelated NewsJul 19th, 2024

Discovery of a tRNA modification enzyme that also acts on nucleosides

The genetic information on DNA is transcribed into messenger RNA (mRNA) and translated to the amino acid sequence by transfer RNA (tRNA) on the ribosome. Modified nucleosides within RNA are involved in maintaining and regulating the protein synthesis.....»»

Category: topSource:  physorgRelated NewsJul 18th, 2024

Study shows ancient viruses fuel modern-day cancers

Peek inside the human genome and, among the 20,000 or so genes that serve as building blocks of life, you'll also find flecks of DNA left behind by viruses that infected primate ancestors tens of millions of years ago......»»

Category: topSource:  physorgRelated NewsJul 17th, 2024

Study shows how narcissistic CEOs influence boards of directors to take more risk

Narcissistic CEOs who also serve as chairs of the board are adept at controlling how their boards of directors focus their attention, giving the CEO the ability to get their way. A new study published in the Strategic Management Journal has found tha.....»»

Category: topSource:  physorgRelated NewsJul 16th, 2024

Arduino’s Plug and Make Kit lets your hacking imagination run wild, sans solder

Daisy-chain tiny boards into weather stations, game controllers, and way more. Enlarge / Having this on the wall, right by your front door, would serve the purpose of informing guests where your priorities lie. (credit: Arduino).....»»

Category: topSource:  arstechnicaRelated NewsJul 12th, 2024

Understanding the role of RNA methylation in cancer

RNA modification could serve as a therapeutic target for certain types of cancer, according to a new study published in Molecular Cell, which sheds new light on the complex process underlying RNA transcription......»»

Category: topSource:  physorgRelated NewsJul 12th, 2024

Study: Nanoparticle vaccines enhance cross-protection against influenza viruses

To offer cross-protection against diverse influenza virus variants, nanoparticle vaccines can produce pivotal cellular and mucosal immune responses that enhance vaccine efficacy and broaden protection, according to a study by researchers in the Insti.....»»

Category: topSource:  physorgRelated NewsJul 10th, 2024

A Combination COVID and Flu Vaccine Is Coming Soon

The first large trial of a COVID and flu vaccine combo suggests it boosts immune protection even more than single-target shots.....»»

Category: scienceSource:  sciamRelated NewsJul 10th, 2024

Study investigates the nature of very-high energy gamma-ray source TeV J2032+4130

Using the High-Altitude Water Cherenkov (HAWC) observatory, an international team of astronomers has observed a very-high energy gamma-ray source designated TeV J2032+4130. Results of the observational campaign, presented July 3 on the preprint serve.....»»

Category: topSource:  physorgRelated NewsJul 10th, 2024

Team pioneers a "one-pot platform" to promptly produce mRNA delivery particles

Imagine a scenario where a skilled hacker must upload critical software to update a central server and thwart a potentially lethal virus from wreaking havoc across a vast computer network. The programmer, armed with the lifesaving code, must navigate.....»»

Category: topSource:  physorgRelated NewsJul 9th, 2024

US Government Awards Moderna $176 Million for mRNA Bird Flu Vaccine

As fears of a pandemic mount, the biotech company’s mRNA vaccine trial is set to release Phase 1/2 results later this year, with a larger Phase 3 trial expected to begin in 2025......»»

Category: gadgetSource:  wiredRelated NewsJul 5th, 2024

Deepwatch appoints John DiLullo as CEO

Deepwatch announced that John DiLullo has been appointed as CEO, succeeding Charlie Thomas who is retiring and will serve as chairman of the Board of Directors, effective immediately. John DiLullo is a veteran of the cybersecurity industry with more.....»»

Category: securitySource:  netsecurityRelated NewsJul 3rd, 2024

New mRNA technology turns cells into long-lasting drug factories

A team of researchers has established a ribonucleic acid (RNA)-based method that drives cells in the body to produce therapeutic proteins and secrete them into the bloodstream. The approach could potentially extend the lifespan of drugs in the body,.....»»

Category: topSource:  physorgRelated NewsJul 3rd, 2024

US prepares for bird flu pandemic with $176M Moderna vaccine deal

Phase 3 trial is expected to begin next year. Enlarge (credit: Getty | Justin Sullivan) The US government will pay Moderna $176 million to develop an mRNA vaccine against a pandemic influenza—an award given as the high.....»»

Category: topSource:  arstechnicaRelated NewsJul 3rd, 2024

How many giraffe species are there? Understanding this maybe key to their protection

Giraffes, with their distinctive body shape and variations in coat patterns, have long been an example in evolutionary biology teachings. They are a textbook example of how species adapt to their surroundings and survive under harsh conditions. Despi.....»»

Category: topSource:  physorgRelated NewsJun 1st, 2024

PSA: MagSafe probably isn’t charging your iPhone when using Continuity Camera

iPhones are powerful pocket computers with advanced chips, price tags largely exceeding $1,000, and they’re at the center of much of our lives. They also, since Apple debuted Continuity Camera in macOS Ventura, serve as pretty great alternatives to.....»»

Category: topSource:  theglobeandmailRelated NewsJun 1st, 2024

Scientists are testing mRNA vaccines to protect cows and people against bird flu

The bird flu outbreak in U.S. dairy cows is prompting development of new, next-generation mRNA vaccines—akin to COVID-19 shots—that are being tested in both animals and people......»»

Category: topSource:  physorgRelated NewsMay 31st, 2024

Misleading COVID-19 headlines from mainstream sources did more harm on Facebook than fake news, study finds

Since the rollout of the COVID-19 vaccine in 2021, fake news on social media has been widely blamed for low vaccine uptake in the United States—but research by MIT Sloan School of Management Ph.D. candidate Jennifer Allen and Professor David Rand f.....»»

Category: topSource:  physorgRelated NewsMay 30th, 2024

As bird flu spreads in cows, US close to funding Moderna’s mRNA H5 vaccine

If trials are successful, US government likely to buy doses for vaccine stockpile. Enlarge (credit: Digicom Photo/Science Photo Library via Getty) The US government is nearing an agreement to bankroll a late-stage trial.....»»

Category: topSource:  arstechnicaRelated NewsMay 30th, 2024