Downstream RNA hairpins found orchestrating mRNA translation
Research led by Duke University, Durham, has discovered a situation-dependent traffic jam in mRNA translation caused by RNA hairpins leading to higher translation of upstream start codons (uAUGs)......»»
Taiwanese PCB supply chain expands capacity across Asia, with Indian focus
PCB production used to be heavily concentrated in Kunshan, China and Taiwan. However, recent changes in the global economy and politics, as well as growing geopolitical conflicts, have led both upstream material suppliers and downstream rigid and fle.....»»
Don’t miss Ars Frontiers 2023: Top minds talk AI, mRNA, and TikTok bans
Everyone is invited to join us for our (free!) event, streaming live on May 22. Enlarge (credit: Aurich Lawson) Ars Technica is pleased to announce the return of Ars Frontiers, our single-day event that explores tech's m.....»»
Global server shipments to see slight sequential growth in 2Q23 amid cloud service boom
Upstream and downstream players in the electronics industry remained at the inventory adjustment stage in the first quarter of 2023, with their revenue performance mostly stalling and even declining compared to the same period of 2022......»»
Rare myocarditis after COVID shots: Study rules out some common culprits
Researchers ruled out overexuberant antibodies in an autoimmune response. Enlarge / Heart scan. (credit: Getty | BSIP) The mRNA-based COVID-19 vaccines have proven remarkably safe and effective against the deadly pandemi.....»»
Biocatalytic synthesis of pseudouridine for cheaper mRNA vaccines
Researchers from the Institute of Biotechnology and Biochemical Engineering at TU Graz and the Austrian Center of Industrial Biotechnology (ACIB) have developed a novel method for the production of central components of mRNA vaccines and applied for.....»»
Hidden RNA repair mechanism discovered in humans
Ribonucleic acids (RNAs) are single-stranded molecules that play an essential role in the cells of all living organisms. As "transcripts" of our genes, mRNAs, for example, are involved in the translation of genetic information by carrying in their ow.....»»
Establishing the basis for mammalian intracellular computing with mRNA switches
Professor Hirohide Saito and his research team have developed a new approach to control mRNA translation using Cas proteins, thus expanding the variety of mRNA switches and making it easier to build synthetic gene circuits in mammalian cells. The res.....»»
Study reveals pivotal RNA modification in mouse embryos
RNA, specifically mRNA, has enjoyed a bit of publicity recently as the main component of the COVID-19 vaccines......»»
COVID vaccines: FDA retires monovalent shots, offers spring boosters to some
The original monovalent COVID-19 mRNA shots are no longer authorized in the US. Enlarge / A pharmacist holds a bottle containing Moderna's bivalent COVID-19 vaccine. (credit: Getty | Mel Melcon) The Food and Drug Adminis.....»»
Terminal devices sales starting to show signs of turning around
There is a clear gap between upstream and downstream electronics and semiconductor players in terms of detectable market conditions, with the former slowing down capacity expansions amid sustained order cuts from customers and the latter beginning to.....»»
Fragment of a 1,750-year-old New Testament translation discovered
About 1,300 years ago a scribe in Palestine took a book of the Gospels inscribed with a Syriac text and erased it. Parchment was scarce in the desert in the Middle Ages, so manuscripts were often erased and reused......»»
Humans vs. bacteria: Differences in ribosome decoding revealed
Scientists at St. Jude Children's Research Hospital revealed that human ribosomes decode messenger RNA (mRNA) 10 times slower than bacterial ribosomes, but do so more accurately. The study, published today in Nature, used a combination of field-leadi.....»»
Nanoparticle with mRNA appears to prevent, treat peanut allergies in mice
Peanut allergies affect 1 in 50 children, and the most severe cases lead to a potentially deadly immune reaction called anaphylactic shock......»»
Lipid nanoparticles engineered to specifically target pancreas in mouse model
Therapeutics that use mRNA—like some of the COVID-19 vaccines—have enormous potential for the prevention and treatment of many diseases. These therapeutics work by shuttling mRNA "instructions" into target cells, providing them with a blueprint t.....»»
Lipid nanoparticles stimulate innate immune cells more efficiently in younger individuals, finds study
Although the mRNA COVID-19 vaccines from Pfizer-BioNTech and Moderna are safe and effective at preventing severe illness in adults and children, including immunocompromised individuals, researchers have noticed that these shots continue to be the mos.....»»
Notebook demand unlikely to see major recovery in 2Q23
Notebook ODMs continue to witness feeble orders from downstream clients for the second quarter, despite their original expectation of enjoying rising orders every quarter starting the first quarter in 2023, according to sources from the upstream supp.....»»
IC Design White Paper - Discussing strengths and weaknesses of Taiwan"s IC design sector
The strengths of Taiwan's IC design sector include excellent and dedicated STEM talent, a complete semiconductor industry ecosystem from upstream to downstream, and a well-developed downstream ICT (information and communications technology) industry.....»»
RNA vaccination in rabbit mothers confers benefits to offspring in the womb, shows study
Newly developed mRNA vaccines against Zika virus and HIV-1 produced strong antibody responses that transferred from pregnant rabbits to their offspring, researchers report in the journal Molecular Therapy. As noted by the authors, the results support.....»»
Fluentalk T1 means never getting lost in translation again
Are you traveling to a foreign country? Maybe you work with people who speak a different language from you. If that is the case, then the Fluentalk T1 could be the perfect tool. Visiting a foreign country can sometimes feel a bit intimida.....»»
China approves its first mRNA Covid-19 vaccine
China has approved its first Covid-19 vaccine based on mRNA technology, months after the country lifted strict pandemic measures......»»