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Downstream RNA hairpins found orchestrating mRNA translation

Research led by Duke University, Durham, has discovered a situation-dependent traffic jam in mRNA translation caused by RNA hairpins leading to higher translation of upstream start codons (uAUGs)......»»

Category: topSource:  physorgSep 8th, 2023

Rise of the RNA machines: Self-amplification in mRNA vaccine design

The next generation of self-replicating mRNA vaccines could have fewer side effects such as fever, headache and fatigue. This would partly result from the application of artificial intelligence in vaccine development. This is the prediction of Gorben.....»»

Category: topSource:  physorgRelated NewsJun 29th, 2023

Google reportedly gives up on making AR glasses—for the third time

Project Iris said to be scrapped as Google focuses on AR software. Enlarge / A Google video promoted AR's translation potential with these normal-looking consumer AR glasses a year ago, but Google's reportedly quit developing AR.....»»

Category: topSource:  arstechnicaRelated NewsJun 29th, 2023

YouTube video translation is getting an AI-powered dubbing tool upgrade

YouTube will incorporate Google's Aloud tech to create a tool that can generate create multi-lingual video dubs.....»»

Category: topSource:  theglobeandmailRelated NewsJun 23rd, 2023

Nucleoside analogs for messenger RNA metabolic labeling and sequencing

High-throughput RNA-sequencing (RNA-seq) is widely used to profile global cellular gene expression and gain insights into cellular biological processes; however, effectively tracking dynamic changes in cellular mRNA expression remains a challenge. Be.....»»

Category: topSource:  physorgRelated NewsJun 21st, 2023

Scientists quantify regulation factors contributing to flux changes in the central metabolic pathway in yeast

Metabolic reaction flux change is the final result of interacting regulations by intracellular gene expression, transcriptional regulation, protein level, translation modification, and allosteric effect. However, the regulatory mechanism of metabolic.....»»

Category: topSource:  physorgRelated NewsJun 20th, 2023

Retooling the ribosomal translation machine could expand chemical repertoire of cells

Synthetic biologists have become increasingly creative in engineering yeast or bacteria to churn out useful chemicals—from fuels to fabrics and drugs—beyond the normal repertoire of microbes......»»

Category: topSource:  physorgRelated NewsJun 13th, 2023

mRNA Vaccines Could Prevent Diseases in Farm Animals

There are safeguards to ensure they won’t end up in your food.....»»

Category: scienceSource:  sciamRelated NewsJun 9th, 2023

LED firms see revenue improve in May

Most Taiwan-based LED chipmakers and packaging houses, including Ennostar and Everlight, posted sequential revenue gains in May as demand from downstream customers began to warm up, according to industry sources......»»

Category: itSource:  digitimesRelated NewsJun 9th, 2023

J&J’s COVID vaccine is dead in the US; FDA revokes authorization

The withdrawal leaves the two mRNA vaccines and the Novavax protein subunit vaccine. Enlarge / Boxes of Johnson & Johnson's Janssen COVID-19 vaccine at a vaccination site in Florida. (credit: Getty | Paul Hennessy) The F.....»»

Category: topSource:  arstechnicaRelated NewsJun 6th, 2023

How we are contaminating our waters with microplastics and a multitude of chemicals

A plastic sandwich wrapper bobs in the water where the Limmat River flows out of Lake Zurich. The current carries it downstream through Zurich's historic center before eventually depositing it on the bank of Werd island. Exposed to sunlight, it gradu.....»»

Category: topSource:  pcmagRelated NewsJun 6th, 2023

New DirectX 12-to-Metal translation could bring a world of Windows games to macOS

CrossOver announces early, case-by-case support for Windows' current gaming API. Enlarge / This Diablo II Resurrected screenshot looks pretty unremarkable until you zoom into the top-right and see that it's running on an Apple M2.....»»

Category: topSource:  arstechnicaRelated NewsJun 5th, 2023

Missing link explains mRNA delivery in brain cells

Brain cells manufacture proteins in every corner, including their long branches. Neurons missing this ability cause severe neurological disorders like disability and epilepsy. The groups of Marino Zerial, Max Planck Institute (MPI) of Molecular Cell.....»»

Category: topSource:  physorgRelated NewsJun 2nd, 2023

Memory chipmakers and module houses seek to stabilize prices

Memory chipmakers have shown downstream customers that they will no longer sell at low prices, while module manufacturers with high levels of inventory are eager to see spot market prices stabilize, according to industry sources......»»

Category: itSource:  digitimesRelated NewsJun 2nd, 2023

Researchers tell owners to “assume compromise” of unpatched Zyxel firewalls

Poor patching hygiene is fueling a flurry of "downstream attacks" on other targets. Enlarge (credit: Getty Images) Firewalls made by Zyxel are being wrangled into a destructive botnet, which is taking control of them by.....»»

Category: topSource:  arstechnicaRelated NewsJun 1st, 2023

mRNA technology for vaccines and more: An Ars Frontiers recap

The tech has lots of applications beyond the one we've already been injected with. Enlarge / On May 22, John Timmer (left) moderated a panel featuring Karin Bok (center) and Nathaniel Wang (right) for the Ars Frontiers 2023 sessi.....»»

Category: topSource:  arstechnicaRelated NewsMay 31st, 2023

Ars Frontiers is live: Come (virtually) hang out with the experts

We're now live with an afternoon of mRNA, artificial intelligence, and space. The Frontiers livestream. Your favorite Ars writers will appear inside of this magic box starting at 1:30 pm US Eastern Daylight Time! It's Frontiers Day.....»»

Category: topSource:  arstechnicaRelated NewsMay 22nd, 2023

Ars Frontiers is here: Come (virtually) hang out with the experts

Starting at 13:30 EDT, it's an afternoon of mRNA, artificial intelligence, and space. The Frontiers livestream. Your favorite Ars writers will appear inside of this magic box starting at 1:30 pm US Eastern Daylight Time! It's Fronti.....»»

Category: topSource:  arstechnicaRelated NewsMay 22nd, 2023

Ars Frontiers is Monday, May 22: Top minds talk AI, mRNA, and TikTok bans

Everyone is invited to our (free!) event, streaming live this coming Monday! Enlarge (credit: Aurich Lawson) Updated: We're almost there! Ars Frontiers is next Monday, May 22, and the show gets started at 13:30 US Easter.....»»

Category: topSource:  arstechnicaRelated NewsMay 19th, 2023

Vaccines using mRNA can protect farm animals against diseases traditional ones may not

While effective vaccines for COVID-19 should have heralded the benefits of mRNA vaccines, fear and misinformation about their supposed dangers circulated at the same time. These misconceptions about mRNA vaccines have recently spilled over into worri.....»»

Category: topSource:  physorgRelated NewsMay 17th, 2023

Long-sought universal flu vaccine: mRNA-based candidate enters clinical trial

The phase I trial will test safety and efficacy in a small number of people. Enlarge / The flu virus, showing the H and N proteins on its surface. (credit: CDC) An mRNA-based flu vaccine designed to offer long-lasting p.....»»

Category: topSource:  arstechnicaRelated NewsMay 17th, 2023