Lipid nanoparticles engineered to specifically target pancreas in mouse model
Therapeutics that use mRNA—like some of the COVID-19 vaccines—have enormous potential for the prevention and treatment of many diseases. These therapeutics work by shuttling mRNA "instructions" into target cells, providing them with a blueprint t.....»»
A 41-million-digit prime number is the biggest ever found—but mathematicians" search for perfection will continue
Imagine a number made up of a vast string of ones: 1111111…111. Specifically, 136,279,841 ones in a row. If we stacked up that many sheets of paper, the resulting tower would stretch into the stratosphere......»»
Study finds private equity targets firms with earnings myopia
What makes private equity firms target a publicly traded company for takeover? A new study from the University of Iowa published in the journal Review of Accounting Studies finds that private equity is often likely to target firms that more aggressiv.....»»
Theoretical model explains the anomalous properties of water in extreme conditions
Water, a molecule essential for life, has unusual properties—known as anomalies—that define its behavior. However, there are still many enigmas about the molecular mechanisms that would explain the anomalies that make the water molecule unique. D.....»»
Hands-on with AirPods 4: better in every way
, and they are awesome. As a pair of on-ear wireless earbuds, they are really hard to fault. I have used AirPods 2 for the past five years — skipping the third-generation model due to fit concerns — and AirPods 4 are what I have been waiting for.....»»
Researchers use high-resolution images to create model that predicts landslide risk in coastal areas
São Sebastião, a municipality on the coast of São Paulo state in Brazil that was partially cut off from the rest of the country in February 2023 after a period of torrential rain, had more than 1,000 landslide points, according to an inventory pro.....»»
Best Samsung Galaxy S24 Ultra deals: Get Samsung’s flagship for $200
If you're planning to buy the top-of-the-line model of Samsung's current lineup of flagship smartphones, check out the best Samsung Galaxy S24 Ultra deals......»»
Is a Xumo TV worth it?
Last week, Xumo announced that it’s bringing a 55- and 65-inch TV to Target for $250 and $360, respectively, both from manufacturer Hisense. While neither of these TVs are new to the world (Hisense Xumo TVs have been exclusively available at Best B.....»»
M4 Mac mini review: The first redesign in years hides incredible computing power
Apple's long-overdue overhaul of the Mac mini shrinks an already great package even more, yet it still punches far above its weight class.M4 Mac miniI've owned a Mac mini since the very first G4 model. In an era of bulky towers and a G4 Cube just yea.....»»
Trump says Elon Musk will lead “DOGE,” a new Department of Government Efficiency
Musk's Department of Government Efficiency to target "massive waste and fraud." President-elect Donald Trump today announced that a new Department of Government Efficiency—or "D.....»»
AirPods Pro crackling issue target of new class-action lawsuit
A class-action lawsuit is accusing Apple of false advertising, claiming the crackling issue of the first-gen AirPods Pro go against Apple's marketing promises.AirPods ProFiled on November 1 in the United States District Court for the Northern Distric.....»»
Simple model system can break down fibrils to investigate drugs for neurodegenerative diseases
The origin of many diseases such as Alzheimer's or Parkinson's can be found at the molecular level in our body, in other words, in proteins. In a healthy system, these proteins are responsible for numerous physiological functions......»»
How are nanostructures created? Imaging techniques unveil secrets of electrodeposition
Metallic nanoparticles, consisting of a few to several thousand atoms or simple molecules, are attracting significant interest. Electrodes coated with layers of nanoparticles (nanolayers) are particularly useful in areas such as energy production, se.....»»
Improved lipid-polymer nanoparticle could advance inhalable mRNA medications and vaccines
Most people don't enjoy getting shots for treatments or vaccines. So, researchers are working to create more medicines, such as those made from messenger RNA (mRNA), that can be sprayed and inhaled......»»
Apple"s M4 Max 14-inch MacBook Pro is on sale for $2,999 & in stock
This popular M4 Max configuration packs a 32-core GPU and 1TB storage, making it a well-equipped model that's $200 off and in stock now.Pick up this M4 Max MacBook Pro at a discount - Image credit: AppleTo grab the $200 discount, head over to Apple A.....»»
Most US book bans target children"s literature featuring diverse characters and authors of color
Book bans in U.S. schools and libraries during the 2021-22 school year disproportionately targeted children's books written by people of color—especially women of color—according to a peer-reviewed study we published. They also tended to feature.....»»
From pets to pests: Researchers explore new tool to fight disease-carrying insects
Arkansas researchers are testing a product commonly used to treat ticks and fleas on pets to target fly and mosquito larvae with the goal of helping reduce the spread of diseases carried by these insects......»»
Global convection-permitting model accurately predicts plum rain event
The plum rain is a persistent and extensive rainfall phenomenon that frequently occurs in East Asia during summer, primarily affecting regions along the latitudes of the middle and lower reaches of the Yangtze River in China to the Kyushu Island in J.....»»
EU sustainable finance framework must go further to meet Paris Climate Goals—research shows how
New research shows that the EU's sustainable finance framework urgently needs to expand and that, in its current form, the taxonomy will not meet the Paris Climate Agreement target of limiting global temperature rise to 1.5°C......»»
Virtual fruity fly model can simulate sensory navigation
All animals, large or small, have to move at an incredible precision to interact with the world. Understanding how the brain controls movement is a fundamental question in neuroscience. For larger animals, this is challenging because of the complexit.....»»
BlackFog platform enhancements boost data loss prevention
BlackFog launched its next generation enterprise platform to deliver even more powerful ransomware and insider threat prevention. BlackFog’s pioneering platform focuses specifically on anti data exfiltration to prevent unauthorized data from leavin.....»»