Discovery of a cellular uptake pathway for larger drug molecules
Recent findings by UCSF and Arc Institute scientists open up new possibilities for overcoming a fundamental challenge in drug discovery. There can be a tradeoff between optimizing a drug's key-in-a-lock fit with its target and the drug's ability to m.....»»
How a PhD Student Discovered a Lost Mayan City From Hundreds of Miles Away
WIRED spoke with the researchers responsible for the discovery of Valeriana, a lost Maya city in the middle of the jungle of Campeche......»»
One more year of the iMac Pro being missing in action
The iMac Pro was totally absent from Apple’s October Mac announcements. Is the company still working on releasing a larger iMac, or is it gone for good?.....»»
Dora Richardson Took Her Research Underground to Develop Lifesaving Tamoxifen
When chemist Dora Richardson’s employer decided to terminate the breast cancer research on the drug Tamoxifen in the early 1970s, she and her colleagues continued the work in secret......»»
New Prime Number, 41 Million Digits Long, Breaks Math Records
The discovery of a new prime number highlights the rising price of mathematical gold.....»»
Chiral molecular self-assemblies that absorb light boost singlet fission process, research demonstrates
In organic molecules, an exciton is a particle bound pair of an electron (negative charge) and its hole (positive charge). They are held together by Coulombic attraction and can move within molecular assemblies. Singlet fission (SF) is a process wher.....»»
Researchers challenge longstanding theories in cellular reprogramming
A team led by researchers at the University of Toronto has discovered that a group of cells located in the skin and other areas of the body, called neural crest stem cells, are the source of reprogrammed neurons found by other researchers......»»
Researchers seek understanding of early life on earth following Chilean expedition
In a discovery that may further our understanding of the early evolution of life on Earth, a research team, including associate professor Andrew Palmer and master's student Caitlyn Hubric, identified Chile's deepest and most northern cold seeps—ope.....»»
The new M4 Mac mini buys Apple time for a larger iMac
While we were very confident beforehand that we wouldn’t be seeing a larger iMac this week, there are still plenty of people waiting impatiently for at least a new 27-inch iMac. Many are hoping for 30-inch, 32-inch, or even bigger. But while I d.....»»
Safe, efficient method for synthesizing allenes opens up new possibilities for drug development
A research team jointly led by Professor Sung You Hong and Professor Jan-Uwe Rohde has unveiled a novel method for synthesizing allenes—a series of compounds integral to drug development and synthetic chemistry—without relying on hazardous, highl.....»»
International team discovers small molecules that regulate how fast plant leaves age
Two small molecules that are produced by the plant Arabidopsis thaliana are shown to have the opposite effect on how fast its leaves age. The molecules are peptides, short chains of amino acids. While the peptide SCOOP10 accelerates aging, SCOOP12 su.....»»
Single-molecule tracking technology streamlines drug discovery
New drug discovery is a critical step for improving patients' lives. First, researchers must identify molecules in the body's cells that help drive disease, as these are potential targets for new drugs. The next step is to screen candidate drugs that.....»»
Ancient Mayan city discovered via page 16 of Google search results
Who ever goes beyond page one of Google search results? Well, Luke Auld-Thomas did, and it led to the discovery of a lost city......»»
Astrophysics study explores turbulence in molecular clouds
On an airplane, motions of the air on both small and large scales contribute to turbulence, which may result in a bumpy flight. Turbulence on a much larger scale is important to how stars form in giant molecular clouds that permeate the Milky Way......»»
Novel polypeptide-based molecules could pave the way for enhanced polymer design
A research study describes a systematic high-throughput design approach for virtual screening and creation of novel polypeptide-based molecules that form regular secondary structures that can be used in biology or materials science research. The stud.....»»
Discovery challenges existing theories of magnetism in kagome metals
A discovery by Rice University physicists and collaborators is unlocking a new understanding of magnetism and electronic interactions in cutting-edge materials, potentially revolutionizing technology fields such as quantum computing and high-temperat.....»»
Researchers observe stick-slip phenomenon in carbon nanotube fibers
The shapes of simple polyatomic molecules such as carbon dioxide and methane are characterized by a specific symmetry depending on the manner of linking of the atoms. Nano- to micrometer-sized particles that mimic the shapes of such polyatomic molecu.....»»
Quantum simulator could help uncover materials for high-performance electronics
Quantum computers hold the promise to emulate complex materials, helping researchers better understand the physical properties that arise from interacting atoms and electrons. This may one day lead to the discovery or design of better semiconductors,.....»»
Large meltwater accumulation revealed inside Greenland Ice Sheet
A new study published in Nature unveils a surprising discovery: a substantial amount of meltwater is temporarily stored within the Greenland Ice Sheet during summer months. For the first time, an international group of researchers was able to quantif.....»»
Study finds key protein aids nutrient transport within plant cells
Botanists have come to understand the channels and transporters involved in the uptake and transport of nutrients, yet how are they positioned where they need to be?.....»»
Coral exudates, not algae, linked to bacterial growth that threaten reefs
A study led by the University of Bremen suggests that on algae-dominated coral reefs, it is not the algae but the corals themselves that may contribute to the growth of harmful bacteria. This discovery suggests that a disturbance in the natural compo.....»»