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Discovery of a cellular uptake pathway for larger drug molecules

Recent findings by UCSF and Arc Institute scientists open up new possibilities for overcoming a fundamental challenge in drug discovery. There can be a tradeoff between optimizing a drug's key-in-a-lock fit with its target and the drug's ability to m.....»»

Category: topSource:  marketingvoxDec 8th, 2022

Study identifies compounds that extend longevity of Japanese morning glory flowers

The longevity of plant flowers is controlled by genetically programmed mechanisms. After a certain amount of time after flowering, the expression of genes associated with programmed cell death is induced and cellular components such as proteins and n.....»»

Category: topSource:  physorgRelated NewsOct 3rd, 2024

Quantum researchers come up with a recipe that could accelerate drug development

University of Copenhagen mathematicians have developed a recipe for upgrading quantum computers to simulate complex quantum systems, such as molecules. Their discovery brings us closer to being able to predict how new drugs will behave within our bod.....»»

Category: topSource:  physorgRelated NewsOct 3rd, 2024

Solid electrolyte composed of nanoparticles shows promise for all-solid-state batteries

Often overlooked, rechargeable batteries play an important part in contemporary life, powering small devices like smartphones to larger ones like electric vehicles. The keys to creating sustainable rechargeable batteries include having them hold thei.....»»

Category: topSource:  physorgRelated NewsOct 2nd, 2024

Citizen scientists create buzz with new insect discovery

More than 60% of Australia's known insects are unnamed and a mystery to science. Of an estimated 500,000 Australian species, roughly half are insects, but many aren't categorized......»»

Category: topSource:  physorgRelated NewsOct 2nd, 2024

New triple star system sets shortest orbital period record

Professional and amateur astronomers have made a groundbreaking discovery with the help of artificial intelligence, identifying a unique triple star system named TIC 290061484. This stellar trio was uncovered through cosmic "strobe lights" observed b.....»»

Category: topSource:  physorgRelated NewsOct 2nd, 2024

Preserving nature"s genetic resources: Wild banana relatives of mainland Southeast Asia reveal hidden diversity

In a new study, researchers have uncovered a wealth of hidden diversity among wild banana species in mainland Southeast Asia. The discovery, which has been published in PLoS ONE, highlights the critical importance of conserving these genetic resource.....»»

Category: topSource:  physorgRelated NewsOct 2nd, 2024

New super-Neptune exoplanet discovered

An international team of astronomers reports the discovery of a new super-Neptune exoplanet orbiting a solar-type star. The newly detected alien world, which received the designation TOI-5005 b, is about six times larger and more than 30 times more m.....»»

Category: topSource:  physorgRelated NewsOct 2nd, 2024

Planning a drug"s route in the body with synthetic chemistry

Researchers at the RIKEN Cluster for Pioneering Research (CPR) have developed technology that can alter, within the body, the recognized identity of proteins......»»

Category: topSource:  physorgRelated NewsOct 2nd, 2024

Predicting river flow dynamics using stable isotopes for improved ecosystem health

An international science team has made significant strides in understanding river flow dynamics. The findings leverage isotope hydrology techniques such as measuring stable isotopes in water molecules to elucidate the contributions of various water s.....»»

Category: topSource:  physorgRelated NewsOct 1st, 2024

Seeing double: Designing drugs that target "twin" cancer proteins

Some proteins in the human body are easy to block with a drug; they have an obvious spot in their structure where a drug can fit, like a key in a lock. But other proteins are more difficult to target, with no clear drug-binding sites......»»

Category: topSource:  physorgRelated NewsOct 1st, 2024

3D structure of key protein could advance development of hormone-free male contraceptive pill

Melbourne-based scientists behind the development of a hormone-free, reversible male contraceptive pill have, for the first time, solved the molecular structure of the discovery program's primary therapeutic target, significantly increasing the chanc.....»»

Category: topSource:  theglobeandmailRelated NewsOct 1st, 2024

Fluorescent molecules to illuminate life: Simplified synthesis with formaldehyde

A research team has recently made a breakthrough in synthesizing organic fluorophores more cost-effectively and atom-efficiently than ever before by using formaldehyde, the simplest carbon molecule. Their findings were published in Angewandte Chemie.....»»

Category: topSource:  physorgRelated NewsSep 30th, 2024

Over half of Americans say lowering health care costs is among most important issues in deciding their presidential pick

Lowering the cost of health care and prescription drug prices and protecting Medicare and Social Security are among the most important issues for Americans in determining their vote for president, according to a new national West Health-Gallup Poll r.....»»

Category: topSource:  physorgRelated NewsSep 30th, 2024

How to use iPhone Emergency SOS via satellite

Apple’s Emergency SOS iPhone via satellite feature is available in 17 countries. Read on for how to test iPhone Emergency SOS messages via satellite to learn how it works and how to use it in a real emergency when there’s no cellular service or W.....»»

Category: topSource:  marketingvoxRelated NewsSep 30th, 2024

Verizon confirms widespread outage affecting users across the US

Verizon is experiencing a massive outage, according to subscribers across the United States. Several of us here at 9to5Mac are also affected by the outage and are unable to an access any sort of cellular connectivity. This includes cellular data, pho.....»»

Category: topSource:  marketingvoxRelated NewsSep 30th, 2024

New insights into sauropod evolution: Discovery of tail clubs in India

A new University of Michigan study of dinosaur fossils from India has revealed that the sauropod dinosaur Kotasaurus yamanpalliensis wielded a bony tail club......»»

Category: topSource:  physorgRelated NewsSep 30th, 2024

Scientists uncover light absorbing properties of achiral materials

Researchers at the University of Ottawa have made a discovery that changes what we know about light and materials. They found that engineered achiral (symmetric) materials, called achiral plasmonic metasurfaces, can absorb light differently depending.....»»

Category: topSource:  physorgRelated NewsSep 30th, 2024

Discovery of 3,775-year-old preserved log supports "wood vaulting" as a climate solution

A new study published in the journal Science suggests that an ordinary old log could help refine strategies to tackle climate change......»»

Category: topSource:  physorgRelated NewsSep 30th, 2024

iFixit’s iPhone 16 teardown finds a greatly improved battery removal process

The new iPhones received a repair score of 7 out of 10. iFixit's iPhone 16 and 16 Plus teardown. iFixit has published teardown views for the iPhone 16 and iPhone 16 Pro, along with their larger cousins, the Plus and Pro Max. The vid.....»»

Category: topSource:  arstechnicaRelated NewsSep 27th, 2024

Bioengineers and chemists design fluorescent 3D-printed structures with potential medical applications

In a process as simple as stirring eggs and flour into pancakes, University of Oregon researchers have mixed fluorescent ring-shaped molecules into a novel 3D printing process. The result: intricate glowing structures that support the development of.....»»

Category: topSource:  physorgRelated NewsSep 27th, 2024