Discovery of a cellular uptake pathway for larger drug molecules
Recent findings by UCSF and Arc Institute scientists open up new possibilities for overcoming a fundamental challenge in drug discovery. There can be a tradeoff between optimizing a drug's key-in-a-lock fit with its target and the drug's ability to m.....»»
Lunar dust dynamics: Unveiling the charging properties and particle behavior of Chang"e-5 samples in an electric field
A study published in Engineering has shed new light on the behavior of lunar regolith particles under the influence of an external electric field, a discovery that could revolutionize space exploration and lunar resource utilization. The research, co.....»»
Machine learning accelerates discovery of high-temperature alloys
In a study recently published in Engineering, scientists from the University of Science and Technology Beijing, Guangdong Ocean University, and AiMaterials Research LLC have demonstrated a novel method to accelerate the discovery of refractory high-e.....»»
Exploring the role of hydrogen sulfide in the expression of iron uptake genes in E. coli
Antibiotic resistance and oxidative stress response are important biological mechanisms that help bacteria thrive, especially pathogenic bacteria like Escherichia coli. Hydrogen sulfide (H2S), a chemical messenger molecule, regulates several intracel.....»»
How a protein keeps gene clusters quiet in the cell nucleolus
In a discovery that sheds light on the complex mechanisms of gene regulation, scientists at EPFL have uncovered a critical role for the protein ZNF274 in keeping certain gene clusters turned off by anchoring them to the cell nucleolus. The study is p.....»»
How iron and metabolic constraints can aid gene discovery for photosynthesis and biofuel production
The single-cell green alga Chromochloris zofingiensis is an emerging model organism for photosynthesis and metabolism research. Previous research has shown that with the addition of glucose, Chromochloris zofingiensis shuts off photosynthesis, rerout.....»»
The biological marvels of the seabed are being mined to create commercial products—here are the risks
Thousands of genes from deep-sea marine life are being used to create new commercial products ranging from pharmaceuticals to cosmetics. Genes are segments of DNA that provide instructions for making other molecules that are essential for the structu.....»»
How large language models are changing collective intelligence
Within teams, organizations, markets and online communities, ideas from a larger group can help to solve complex problems. Large language models (LLMs) are emerging as powerful tools to unlock even greater potential. Picture an online forum where tho.....»»
Orbital angular momentum monopoles discovery propels orbitronics forward in energy-efficient tech
Orbital angular momentum monopoles have been the subject of great theoretical interest as they offer major practical advantages for the emerging field of orbitronics, a potential energy-efficient alternative to traditional electronics. Now, through a.....»»
New method enables noninvasive plant magnetic resonance imaging
The "omics" technologies—genomics, transcriptomics, proteomics, and metabolomics—are at the forefront of discovery in modern plant science and systems biology. In contrast to the rather static genome, however, the metabolome and the products meas.....»»
2025 Audi Q6 E-tron priced from $65,095, gains entry rwd variant at launch
The midsize Q6 E-tron crossover is slotted above the smaller Q4 E-tron and below the larger Q8 E-tron in Audi's lineup......»»
Scientists uncover a critical component that helps killifish regenerate their fins
Spontaneous injuries like the loss of a limb or damage to the spinal cord are impossible for humans to repair. Yet, some animals have an extraordinary capacity to regenerate after injury, a response that requires a precise sequence of cellular events.....»»
Scientists develop method to control timing of synthetic DNA droplet division
Many cellular functions in the human body are controlled by biological droplets called liquid-liquid phase separation (LLPS) droplets. These droplets, made of soft biological materials, exist inside living cells but are not enclosed by membranes like.....»»
Apple Watch Series 10 won’t get these faces despite larger screen than Ultra
The , and the lack of an Apple Watch Ultra 3, has sparked fresh discourse over which Watch model is actually ‘best.’ A key factor in comparing the Series 10 with the Apple Watch Ultra 2 involves software. Both models run watchOS 11, yet despite v.....»»
"Tamed" molecules for more sustainable catalysts: Chemists succeed in synthesizing a spectacular gallium compound
Catalysts play an important role in the manufacture of many products that we encounter in everyday life—for example in cars for exhaust gas purification or in the chemical industry in the production of fertilizers. Catalysts ensure that these react.....»»
AI trained on evolution"s playbook develops proteins that spur drug and scientific discovery
A new artificial intelligence model developed by researchers at The University of Texas at Austin paves the way for more effective and less toxic treatments and new preventive strategies in medicine. The AI model informs the design of protein-based t.....»»
Existence of an Earth-like planet around a dead sun offers hope for our planet"s ultimate survival
The discovery of an Earth-like planet 4,000 light years away in the Milky Way galaxy provides a preview of one possible fate for our planet billions of years in the future, when the sun has turned into a white dwarf, and a blasted and frozen Earth ha.....»»
Small accounts, big decisions: How multiple savings impact retirement payout choices
New study shows that retirees are more likely to cash out smaller retirement accounts instead of turning them into steady income streams, even though they might do the opposite with larger accounts. This choice can hurt their long-term financial secu.....»»
Small firms may offer higher pay due to a lack of market power
Small companies may post higher wages for entry level positions than large companies—potentially attracting better talent, even though the larger companies have more influence on the market, according to new Cornell research......»»
Ingredients used in chewing gum help tilapia survive cold climates
Two common ingredients in ordinary chewing gum—Arabic gum and lecithin—have been found to help improve the overall health of tilapia, helping these fish survive better even in cold climates. This discovery paves the way for raising tilapia for fo.....»»
Ultra-high speed camera for molecules: Attosecond spectroscopy captures electron transfer dynamics
In nature, photosynthesis powers plants and bacteria; within solar panels, photovoltaics transform light into electric energy. These processes are driven by electronic motion and imply charge transfer at the molecular level. The redistribution of ele.....»»