Converting P450 peroxygenase into peroxidase via mechanism-guided protein engineering
Enzyme catalysis is a promising green solution for producing pharmaceuticals, fine chemicals, and biofuels. However, exploring their catalytic promiscuity to expand and enhance the capabilities of enzymes remains challenging......»»
Largest protein yet discovered builds algal toxins
While seeking to unravel how marine algae create their chemically complex toxins, scientists at UC San Diego's Scripps Institution of Oceanography have discovered the largest protein yet identified in biology......»»
Technology to predict the deformation of DNA origami structures induced by DNA-binding molecules
A research team has developed a technology that can quickly predict the mechanochemical shape changes of DNA origami nanostructures. The team includes Professor Do-Nyun Kim's research team from the Department of Mechanical Engineering at The College.....»»
A new mechanism for animal food caching behavior discovered
New research from Hebrew University proposes a novel, non-memory-based mechanism for how animals cache and retrieve food. Instead of relying on memory, the researchers suggest that animals use a neural mechanism similar to hash functions in computing.....»»
Heat stress survival: Unraveling the HsfA2-ACTIN dynamics in lily varieties
A research team has identified that the heat stress transcription factor HsfA2 and actin-interacting protein (AIP) LACTIN interact at the protein level in Lilium longiflorum "White Heaven," mediating gene expression and protecting cells from heat str.....»»
A review of the Epichloë festucae antifungal protein Efe-AfpA
A research team has reviewed the mechanisms behind endophyte-mediated disease resistance in strong creeping red fescue (Festuca rubra subsp. rubra) and identified the antifungal protein Efe-AfpA produced by Epichloë festucae as a key factor against.....»»
How network segmentation can strengthen visibility in OT networks
What role does the firewall play in the protection of operational technology (OT) networks and systems? Many would say that it’s the defensive mechanism to protect that environment from IT and the outside world. For the operators responsible fo.....»»
3D-printed blood vessels bring artificial organs closer to reality
Growing functional human organs outside the body is a long-sought "holy grail" of organ transplantation medicine that remains elusive. New research from Harvard's Wyss Institute for Biologically Inspired Engineering and John A. Paulson School of Engi.....»»
How ribosomes in our cells enable protein folding
Scientists at UCL have discovered a novel role played by ribosomes during the folding of new proteins in cells, described in their paper in Nature......»»
Scientists take atomic look at a protein complex that grants access to our DNA
To transcribe the information contained in our genes or to repair the dozens of breaks that occur daily in our DNA, our enzymes must be able to directly access the DNA to perform their functions. However, in the cell nucleus, this access is limited b.....»»
How developers can simplify feature engineering
How developers can simplify feature engineering.....»»
Scientists "cautiously optimistic" about AI"s role in drug discovery
The human body contains at least 20,000 different proteins, often called the "workhorses of the cell" because of their role in keeping cells healthy. Each protein consists of a unique string of amino acids that affects its shape and function—or dys.....»»
Researchers demonstrate mechanism that may have stabilized the first RNA molecules
The origins of life remain a major mystery. How were complex molecules able to form and remain intact for prolonged periods without disintegrating? A team at ORIGINS, a Munich-based Cluster of Excellence, has demonstrated a mechanism that could have.....»»
Scientists reveal transport mechanism of norepinephrine transporter and binding mode of small molecule and peptide drugs
Noradrenaline (NA) is an important monoamine neurotransmitter in the nervous system. The noradrenaline transporter (NET) located on the presynaptic membrane can transport NA into presynaptic neurons......»»
Researchers elucidate mechanisms behind protein selectivity in adenosine receptor
In a new study, a multinational research team led by Dr. Adnan Sljoka (RIKEN) and Prof. Akio Kitao (Tokyo Tech), in collaboration with Prof. Scott Prosser (University of Toronto), has carried out experimental and computational studies to elucidate th.....»»
When it comes to DNA replication, humans and baker"s yeast are more alike than different, scientists discover
Humans and baker's yeast have more in common than meets the eye, including an important mechanism that helps ensure DNA is copied correctly, reports a pair of studies published in the journals Science and Proceedings of the National Academy of Scienc.....»»
Climate change may lead to shifts in vital Pacific Arctic fisheries
Marine fisheries are an essential source of protein for a large part of the world's population, as well as supporting around 390 million livelihoods and an industry worth approximately US$ 141 billion, according to the UN FAO. Yet, climate change pre.....»»
Metallic nanosheets curl into nanovesicles
Inspired by the cell membrane structure, researchers, led by Dr. Xiaoqing Huang (State Key Laboratory of Physical Chemistry of Solid Surfaces, College of Chemistry and Chemical Engineering, Xiamen University) and Dr. Qi Shao (College of Chemistry and.....»»
Cado platform enhances SOC efficiency with AI-driven workflow automation
Cado Security has unveiled that the Cado platform now enables customers to dramatically streamline the effectiveness of their SOC using end-to-end workflow investigation automation capabilities. Through the infusion of AI-guided investigations and da.....»»
Take a preventative approach to escape the engineering toil trap
Take a preventative approach to escape the engineering toil trap.....»»
New Boeing boss Kelly Ortberg brings engineering background, aerospace roots
New Boeing boss Kelly Ortberg brings engineering background, aerospace roots.....»»