Converting P450 peroxygenase into peroxidase via mechanism-guided protein engineering
Enzyme catalysis is a promising green solution for producing pharmaceuticals, fine chemicals, and biofuels. However, exploring their catalytic promiscuity to expand and enhance the capabilities of enzymes remains challenging......»»
Engineers use machine learning to measure chaos in systems
How do we measure chaos and why would we want to? Together, Penn engineers Dani S. Bassett, J. Peter Skirkanich Professor in Bioengineering and in Electrical and Systems Engineering, and postdoctoral researcher Kieran Murphy leverage the power of mac.....»»
Organic nanozymes have broad applications from food and agriculture to biomedicine
Nanozymes are tiny, engineered substances that mimic the catalytic properties of natural enzymes, and they serve a variety of purposes in biomedicine, chemical engineering, and environmental applications. They are typically made from inorganic materi.....»»
ACE-ing protein detection in single cells
Since the 1950s, researchers have used a famous method invented by Wallace Coulter known as "flow cytometry" to characterize different types of immune cells in research studies and in blood samples from human individuals. This has enabled a much deep.....»»
Fruitful innovation: Transforming watermelon genetics with advanced base editors
The development of new adenine base editors (ABE) and adenine-to-thymine/guanine base editors (AKBE) is transforming watermelon genetic engineering. These innovative tools enable precise A:T-to-G and A:T-to-T base substitutions, allowing for targeted.....»»
Precise genetics: New CRISPR method enables efficient DNA modification
With the revolutionary CRISPR/Cas technology, the DNA of living organisms can be precisely altered. Using a guide RNA that recognizes a specific DNA sequence, Cas9 protein is recruited to that sequence and cuts the DNA. This targeted cut allows the D.....»»
Best OnePlus Open screen protectors to buy in 2024
Keep your OnePlus Open display safe and protected with these screen protectors. The post Best OnePlus Open screen protectors to buy in 2024 appeared first on Phandroid. The OnePlus Open is a foldable smartphone with a book-style mechanism......»»
Parasite engineered to deliver therapy proteins to nerve cells
An international team of neurobiologists has developed a way to use a parasite to deliver protein therapies through the blood–brain barrier to treat nerve cell disorders. In their study published in Nature Microbiology, the group engineered the par.....»»
Developing new methods for targeted protein degradation
Northwestern Medicine scientists have developed a new, more precise method to target proteins implicated in certain types of cancer, according to a study published in Nature Chemical Biology......»»
Securing remote access to mission-critical OT assets
In this Help Net Security interview, Grant Geyer, Chief Strategy Officer at Claroty, discusses the prevalent vulnerabilities in Windows-based engineering workstations (EWS) and human-machine interfaces (HMI) within OT environments. Geyer also address.....»»
Bike lanes and narrowed streets don’t slow emergency vehicles
People love to complain about traffic calming, but it makes roads safer. Enlarge / Converting this street from two lanes in either direction to one lane in each direction with a turning lane in-between would make it much safer. (.....»»
Scientists develop revolutionary egg white-based bioink for advanced tissue engineering
Terasaki Institute scientists have created a nature-inspired cutting-edge technology by developing a novel bioink derived from egg whites or egg white methacryloyl (EWMA). A paper describing their work is published in the journal Advanced Functional.....»»
Mass breeding of desert locusts unlocks new food source
Mass breeding of desert locusts in a controlled environment could provide a sustainable source of protein for animals and humans as well as business opportunities in Sub-Saharan Africa, researchers say......»»
Carpets and flames: Design rules for the morphology of ciliated organs
The history of science is a series of paradigm shifts—conventional theories debunked and replaced by new discoveries. Kanso Bioinspired Motion Lab at USC Viterbi School of Engineering has made a habit of such paradigm shifts, publishing their findi.....»»
Ice 0: Researchers discover a new mechanism for ice formation
Ice is far more complicated than most of us realize, with over 20 different varieties known to science, forming under various combinations of pressure and temperature. The kind we use to chill our drinks is known as ice I, and it's one of the few for.....»»
AMD’s new flagship chip just did something unprecedented
Leaked benchmark results of a Ryzen 9 9950X engineering sample suggests that consumers may be able to overclock the chip to 6GHz......»»
From trash to treasure: Machine learning enhances organic waste recycling
Biological treatment methods such as anaerobic digestion, composting, and insect farming are essential for managing organic waste, converting it into valuable resources like biogas and organic fertilizers. However, these processes often face challeng.....»»
New 3D reconstruction method aids analysis of property-defining defects
An international research collaboration, including a group from Cornell Engineering, has applied a new X-ray-based reconstruction technique to observe, for the first time, topological defects in a nanoscale self-assembly-based cubic network structure.....»»
Nanoscopic imaging aids in understanding protein, tissue preservation in ancient bones
A pilot study from North Carolina State University shows that nanoscopic 3D imaging of ancient bone not only provides further insight into the changes soft tissues undergo during fossilization, it also has potential as a fast, practical way to determ.....»»
Discovery of Piezo1"s new signaling mechanism may aid search for better pain and itch treatments
The human body's sense of touch is so important it can be found throughout the body, not just on the skin. Two tiny sensors of touch, Piezo1 and Piezo2, signal the lightest pressures and can be found monitoring the circulatory system, telling the bod.....»»
Researchers zero in on the underlying mechanism that causes alloys to crack when exposed to hydrogen-rich environments
When deciding what material to use for infrastructure projects, metals are often selected for their durability. However, if placed in a hydrogen-rich environment, like water, metals can become brittle and fail. Since the mid-19th century, this phenom.....»»