Unfreezing waters in ligand binding sites to aid in drug discovery
Cryogenic (frozen) protein structures are central to understanding function and developing drugs. Scientists at St. Jude Children's Research Hospital have created an algorithm to reveal when freezing the proteins may create "artifacts,"—errors that.....»»
Online dating sites: The size of the potential dating pool makes all the difference
Online dating sites have become one of the more popular means for people to meet each other and explore the potential for a romantic relationship. But did you know that it's the size of the online dating pool that could make or break your own quest f.....»»
Four plants eaten by gorillas, also used in traditional medicine, provide clues for new drug discovery
Four plants consumed by wild gorillas in Gabon and used by local communities in traditional medicine show antibacterial and antioxidant properties, find Leresche Even Doneilly Oyaba Yinda from the Interdisciplinary Medical Research Center of Francevi.....»»
Newly discovered antimicrobial could prevent or treat cholera
More than a million people each year die from infections by pathogens that are resistant to antimicrobials, and the problem is growing. Meanwhile, the discovery of new antimicrobials that can help stem the tide has not kept pace......»»
Discovery of a new phase of matter in 2D defies normal statistical mechanics
Physicists from the Cavendish Laboratory in Cambridge have created the first two-dimensional version of the Bose glass, a novel phase of matter that challenges statistical mechanics. The details of the study have been published in Nature......»»
Why are sharks coming to Boston Harbor? Researchers believe it"s a nursery ground
Once unthinkable when the harbor was nasty and polluted, today's cleaner waters have actually become a desirable shark habitat as young sharks migrate here yearly......»»
Thanks to humans, Salish Sea waters are too noisy for resident orcas to hunt successfully
The Salish Sea—the inland coastal waters of Washington and British Columbia—is home to two unique populations of fish-eating orcas, the northern resident and the southern resident orcas. Human activity over much of the 20th century, including red.....»»
An Amazon river dries up, creating hellish crossing for villagers
Only the youngest and strongest villagers now brave the crossing of a vast, blistering stretch of sand where, in normal times, the waters of the mighty Madeira River flow in the Brazilian Amazon......»»
Discovery unveils new path to ethanol production from CO₂
In a study published in Energy & Environmental Science, researchers from the Interface Science Department at the Fritz Haber Institute have introduced a novel method for converting the greenhouse gas carbon dioxide (CO2) into ethanol, a sustainable f.....»»
Researchers identify new tools for anti-Acinetobacter drug development and AMR preparedness
University of Liverpool researchers have engineered a library of strains that can be used to develop new antibacterial compounds to help address antimicrobial resistance (AMR) in Acinetobacter baumannii bacteria......»»
Shallow waters make the best carbon sinks, researchers find
Marine phytoplankton take up atmospheric carbon and carry it to the seafloor when they die and sink (a process known as organic carbon sedimentation). This biological carbon pump is a powerful part of Earth's carbon cycle, yet scientists don't have a.....»»
Large theropod dinosaurs thrived near South Pole, Australian tracks show
A discovery of dinosaur tracks on Australia's southern coast—dating back to the Early Cretaceous when Australia was still connected to Antarctica—indicates that large theropod dinosaurs thrived in this polar environment, prowling the river floodp.....»»
Artemis III landing sites identified using mapping and algorithm techniques
Where would be the most ideal landing site for the Artemis III crew in SpaceX's Human Landing System (HLS)? This is what a recent study submitted to Acta Astronautica, and available on the arXiv preprint server, hopes to address as an international t.....»»
Biomolecules inside living cells can now be seen with infrared light thanks to new method
To accelerate biotechnology innovations, such as the development of lifesaving drug therapies, scientists strive to develop faster, more quantitative and more widely available ways to observe biomolecules in living cells......»»
Scientists learn how to drug wily class of disease-causing enzymes
UCSF scientists have discovered how to target a class of molecular switches called GTPases that are involved in a myriad of diseases from Parkinson's to cancer and have long been thought to be "undruggable.".....»»
Colombian court orders Escobar"s hippos to be hunted
A Colombian court on Friday called for the hunting of hippos, introduced to the country in the 1980s by drug kingpin Pablo Escobar......»»
ADHD med shortages push DEA to up drug allotment by 23.5%
The DEA's quota increase is for Vyvanse and its generic forms. Enlarge (credit: Getty | George Frey) While supplies of Adderall and its generic versions are finally recovering after a yearslong shortage, the Drug Enforce.....»»
Global experts present early-stage recommendations for nanomedicine development
They're tiny drug-delivery systems 1,000 times smaller than a human hair, but while nanomedicines have long been hailed as the future for treating debilitating and life-threatening diseases, their journey from lab to patient has many challenges......»»
Plant scientists link phospholipid sensing with control of gene expression
Plant scientists have long known that phosphorus is a crucial component in plant growth. A major discovery by a Kansas State University (K-State) biologist and her lab is leading to a better understanding of how plants detect and use that resource—.....»»
Aggressive seagrass species discovered in Biscayne Bay
An invasive species of seagrass has been on a steady march across the world, taking over ecosystems well beyond its native waters of the Red Sea, Persian Gulf and Indian Ocean. Scientists have long wondered when it would reach the waters off the coas.....»»
Researchers develop molecular biosensors that only light up upon binding to their targets
Biosensors—devices that use biological molecules to detect the presence of a target substance—have enormous potential for detecting disease biomarkers, molecules-in-action in diverse biological processes, or toxins and other harmful substances in.....»»