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Unfreezing waters in ligand binding sites to aid in drug discovery

Cryogenic (frozen) protein structures are central to understanding function and developing drugs. Scientists at St. Jude Children's Research Hospital have created an algorithm to reveal when freezing the proteins may create "artifacts,"—errors that.....»»

Category: topSource:  physorgJun 7th, 2022

Have we found all the major Maya cities? Not even close, new research suggests

Archaeologists have analyzed lidar data from a completely unstudied corner of the Maya world in Campeche, Mexico, revealing 6,674 undiscovered Maya structures, including pyramids like those at the famous sites of Chichén Itzá or Tikal......»»

Category: topSource:  pcmagRelated NewsOct 28th, 2024

"Wonder Drug" Explores Thalidomide’s Secret History and Harms in the U.S.

In her book Wonder Drug, Jennifer Vanderbes explores the history of thalidomide’s secret history—and harms—in the U.S......»»

Category: scienceSource:  sciamRelated NewsOct 28th, 2024

Coral record reveals long-term variability of Kuroshio

The Kuroshio is a strong western boundary current in the North Pacific. It transports warm, saltier waters from low to middle latitudes, and has a significant impact on China, East Asia and even the global climate. How the Kuroshio changed before the.....»»

Category: topSource:  physorgRelated NewsOct 28th, 2024

Unique multidomain enzymes from bacteria identified

Pharmaceutical scientists from the National University of Singapore (NUS) have identified and characterized a unique multidomain enzyme capable of catalyzing two distinct types of reactions, both vital for making drug molecules......»»

Category: topSource:  physorgRelated NewsOct 28th, 2024

North Korea says any deployment to aid Russia would be lawful

North Korea says any deployment to aid Russia would be lawful.....»»

Category: topSource:  theglobeandmailRelated NewsOct 26th, 2024

A poor year for juvenile striped bass in Virginia waters in 2024

Preliminary results from an ongoing long-term survey conducted by researchers at William & Mary's Batten School & VIMS suggest that a poor year class of young-of-year striped bass was produced in the Virginia tributaries of the Chesapeake Bay in 2024.....»»

Category: topSource:  physorgRelated NewsOct 25th, 2024

From fireflies to drones: Researchers uncover strategy for synchronization efficiency

Researchers from The University of New Mexico School of Engineering looked to the natural world to explain how synchronized systems can work more efficiently and made a significant discovery. Their results were published in the journal Nature Communi.....»»

Category: topSource:  physorgRelated NewsOct 25th, 2024

VAMMIT trials: Tackling methane emissions in mining

New CSIRO technology that destroys methane at mine sites is showing great promise—and attracting great interest from industry and governments worldwide......»»

Category: topSource:  physorgRelated NewsOct 25th, 2024

Advancing drug delivery: New framework links lipid nanoparticle structure to immune response

A new framework bridges a gap in understanding RNA therapeutics by linking the structure of lipid nanoparticles to immune response. It can help scientists and engineers expand the use of RNA medicines beyond vaccines to other therapeutic applications.....»»

Category: topSource:  physorgRelated NewsOct 25th, 2024

Scientists Photograph Giant Python Swallowing a Full-Sized Whitetail Whole in First-of-Its-Kind Discovery

Scientists Photograph Giant Python Swallowing a Full-Sized Whitetail Whole in First-of-Its-Kind Discovery.....»»

Category: topSource:  marketingvoxRelated NewsOct 25th, 2024

New AirPods Pro 2 firmware now available for iOS 18.1’s hearing health features

Apple has just released new firmware for ahead of iOS 18.1’s launch next week. This firmware update brings support for the powerful new health features: Hearing Test, Hearing Aid, and Hearing Protection. more….....»»

Category: gadgetSource:  9to5macRelated NewsOct 24th, 2024

Alleged ‘Chuco Tango’ gang member arrested on drug-related charges in East El Paso

Alleged ‘Chuco Tango’ gang member arrested on drug-related charges in East El Paso.....»»

Category: topSource:  informationweekRelated NewsOct 24th, 2024

Nanomedicine advances deliver precise antibiotic doses to fight infections and drug resistance

Researchers from the University of Waterloo have developed a new technology that can hold an entire course of antibiotics in one tiny dose and deliver on demand just the right amount of medication that a particular patient needs to fight an infection.....»»

Category: topSource:  physorgRelated NewsOct 24th, 2024

The Maker of Ozempic Is Trying to Block Compounded Versions of Its Blockbuster Drug

Novo Nordisk has asked the FDA to block production of compounded copies of Ozempic, arguing that it’s too difficult to do safely. It’s the latest escalation in a brewing war between pharmaceutical companies and compounders......»»

Category: gadgetSource:  wiredRelated NewsOct 24th, 2024

Researchers piece together 66-million-year-old dinosaur fossils found in South Dakota

The groundbreaking discovery of a 66-million-year-old dinosaur continues to reveal itself years after a piece of it was first spotted, Missouri researchers said......»»

Category: topSource:  physorgRelated NewsOct 24th, 2024

"True hybrid" mice might reveal how new species emerge

Forty years ago, a postdoctoral researcher named James McGrath who would go on to spend more than three decades as a clinical geneticist and research scientist at Yale, made a discovery that advanced scientists' understanding of gene control and the.....»»

Category: topSource:  physorgRelated NewsOct 24th, 2024

GJPD seeking aid in finding suspects in ‘serious crash’

GJPD seeking aid in finding suspects in ‘serious crash’.....»»

Category: topSource:  marketingvoxRelated NewsOct 24th, 2024

Baerbock warns of Lebanon destabilization as Germany pledges €60m aid

Baerbock warns of Lebanon destabilization as Germany pledges €60m aid.....»»

Category: topSource:  marketingvoxRelated NewsOct 24th, 2024

Superconductivity offers new insights into quantum material MnBi₂Te₄

For the first time since the discovery of the material MnBi2Te4 (MBT), researchers at the University of Twente have successfully made it behave like a superconductor. This marks an important step in understanding MBT and is significant for future tec.....»»

Category: topSource:  pcmagRelated NewsOct 23rd, 2024

Drug delivery system overcomes circulatory roadblock that prevents gene therapies from reaching their targets

Exploiting the remarkable capability of viruses to transport gene therapies past what until now has been a circulatory roadblock is at the heart of a University of Alberta-led discovery that promises to re-energize the field of genetic medicine......»»

Category: topSource:  pcmagRelated NewsOct 23rd, 2024