Unfreezing waters in ligand binding sites to aid in drug discovery
Cryogenic (frozen) protein structures are central to understanding function and developing drugs. Scientists at St. Jude Children's Research Hospital have created an algorithm to reveal when freezing the proteins may create "artifacts,"—errors that.....»»
Novel machine learning-based cluster analysis method that leverages target material property
In materials science, substances are often classified based on defining factors such as their elemental composition or crystalline structure. This classification is crucial for advances in materials discovery, as it allows researchers to identify pro.....»»
Smallest arm bone in the human fossil record sheds light on the dawn of Homo floresiensis
A paper appearing today in Nature Communications reports the discovery of extremely rare early human fossils from the Indonesian island of Flores, including an astonishingly small adult limb bone......»»
Astronomers discover new supergiant-rich stellar cluster
Astronomers report the discovery of a new galactic stellar cluster located some 24,000 light years away. The newfound cluster, which received the designation Barbá 2, turns out to host at least several supergiant stars. The finding was detailed in a.....»»
The race to discover biodiversity: 11 new marine species and a new platform for rapid species description
A new paper, the Ocean Species Discoveries (OSD), describes a ground-breaking experiment that united 25 independent taxonomists from ten countries. The initiative boasts the discovery of eleven new marine species from all over the globe, occurring at.....»»
Greenland fossil discovery stuns scientists and confirms that center of ice sheet melted in recent past
The story of Greenland keeps getting greener—and scarier. A new study provides the first direct evidence that the center—not just the edges—of Greenland's ice sheet melted away in the recent geological past and the now-ice-covered island was th.....»»
Oceans without sharks would be far less healthy, says new research
There are more than 500 species of sharks in the world's oceans, from the 7-inch dwarf lantern shark to whale sharks that can grow to over 35 feet long. They're found from polar waters to the equator, at the water's surface and miles deep, in the ope.....»»
HomeKit Weekly: meross smart plug delivers almost everything you’d want in a HomeKit smart plug
Smart plugs are the gateway drug for HomeKit. They’re low-cost and easy to install, and you can get many benefits from them. There are dozens upon dozens of options on where to start, though. The smart plug delivers almost everything you’d want.....»»
New "game-changing" discovery for light-driven artificial intelligence
In a paper, titled "Partial coherence enhances parallelized photonic computing," published in Nature, researchers from the University of Oxford, along with collaborators from the Universities of Muenster, Heidelberg, and Ghent, report that replacing.....»»
Great white sharks secretly roam through Bahamas
It's incredibly rare to spot a great white shark in the waters around the Bahamas, but a new study published in the journal Frontiers in Marine Science shows they visit the area more often than people realize......»»
Scientists "cautiously optimistic" about AI"s role in drug discovery
The human body contains at least 20,000 different proteins, often called the "workhorses of the cell" because of their role in keeping cells healthy. Each protein consists of a unique string of amino acids that affects its shape and function—or dys.....»»
Scientists reveal transport mechanism of norepinephrine transporter and binding mode of small molecule and peptide drugs
Noradrenaline (NA) is an important monoamine neurotransmitter in the nervous system. The noradrenaline transporter (NET) located on the presynaptic membrane can transport NA into presynaptic neurons......»»
Researchers uncover 500 million-year-old mollusk ancestor
A team of researchers including scientists from the University of Oxford have made an astonishing discovery of a new species of mollusk that lived 500 million years ago. The new fossil, called Shishania aculeata, reveals that the most primitive mollu.....»»
Venu Sports finally announces price of $43 a month, for starters
Venu Sports — the new streaming service that combines sports from Disney, Fox, and Warner Bros. Discovery — will cost $43 a month, but that may well increase......»»
The Jasper fire highlights the risks climate change poses to Canada"s world heritage sites
Climate change and extreme weather events pose a real risk to the world's heritage sites—a stark reality laid bare by the recent wildfire in Jasper, Alta......»»
Krill provide insights into how marine species can adapt to warmer waters
Krill in northern waters show how key marine species can adapt genetically to cope with climate change. This discovery was made by researchers at Uppsala University in collaboration with an international research group. According to the researchers,.....»»
Electrical impedance tomography plus extracellular voltage activation technique simplifies drug screening
When developing new drugs, understanding their effects on ion channels in the body, such as the human ether-a-go-go-related gene (hERG) ion channel found in neurons and heart muscle cells, is critical. Blocking hERG channels can disrupt a normal hear.....»»
TIC 441725813 is a hybrid pulsating subdwarf star, study finds
Astronomers have employed NASA's Transiting Exoplanet Survey Satellite (TESS) to observe a subdwarf star designated TIC 441725813. In result, they found that TIC 441725813 is a hybrid hot B subdwarf pulsator. The discovery was detailed in a research.....»»
Google won’t downrank top deepfake porn sites unless victims mass report
Google starts downranking more non-consensual intimate imagery in searches. Enlarge (credit: Paper Boat Creative | Stone) Today, Google announced new measures to combat the rapidly increasing spread of AI-generated non-c.....»»
Cloudflare once again comes under pressure for enabling abusive sites
Cloudflare masks the origin of roughly 10% of abusive domains, watchdog says. Enlarge (credit: Getty Images) A familiar debate is once again surrounding Cloudflare, the content delivery network that provides a free servi.....»»
Researchers put a finger on why men and women feel touch differently
The lab of University of Virginia systems engineer Gregory J. Gerling recently made a discovery on a touchy subject: why women generally seem to have a more acute sense of touch than men......»»