Unfreezing waters in ligand binding sites to aid in drug discovery
Cryogenic (frozen) protein structures are central to understanding function and developing drugs. Scientists at St. Jude Children's Research Hospital have created an algorithm to reveal when freezing the proteins may create "artifacts,"—errors that.....»»
New species of extinct walrus-like mammal discovered in the North Atlantic
A new discovery by a team of paleontologists, led by Dr. Mathieu Boisville (University of Tsukuba, Japan), has uncovered a new species of the extinct genus Ontocetus from the Lower Pleistocene deposits in the North Atlantic. This species, named Ontoc.....»»
The FDA Just Rejected a Bid for MDMA to Treat PTSD
The agency has asked drugmaker Lykos Therapeutics to run an additional study on the use of the psychedelic drug in patients with post-traumatic stress disorder, pushing back its next proposal by years......»»
Discovery of tiny bone sheds light on mysterious "hobbit" humans
The discovery of a tiny arm bone suggests that an ancient human dubbed "hobbits" only shrank down to their diminutive size after they arrived on an Indonesian island a million years ago, scientists said on Tuesday......»»
From fungi to pharmaceuticals: A milestone for the production of eutyscoparol A and violaceoid C
The natural world is rich in chemical compounds with remarkable medicinal properties. A notable example is penicillin, discovered by chance from the Penicillium mold. This discovery revolutionized the treatment of bacterial infections and highlighted.....»»
Ability to track nanoscale flow in soft matter could prove pivotal discovery
For roughly 70 years, Play-Doh has been entertaining children with its moldable, squishy form. This familiar substance belongs to a broader category known as soft matter, which includes some foods (such as mayonnaise), 3D printer gels, battery electr.....»»
Researchers develop AI model that predicts the accuracy of protein–DNA binding
A new artificial intelligence model developed by USC researchers and published in Nature Methods can predict how different proteins may bind to DNA with accuracy across different types of protein, a technological advance that promises to reduce the t.....»»
It’s not worth paying to be removed from people-finder sites, study says
The best removal rate was less than 70%, and that didn't beat manual opt-outs. Enlarge / For a true representation of the people-search industry, a couple of these folks should have lanyards that connect them by the pockets. (cr.....»»
New ligand-guided technique enhances drug development
Achieving a level of precision to create complex medicines and materials with extreme accuracy is a longstanding goal of scientists and pharmaceutical companies. If achieved, that precision could lead to the development of more effective drug treatme.....»»
Technology to predict the deformation of DNA origami structures induced by DNA-binding molecules
A research team has developed a technology that can quickly predict the mechanochemical shape changes of DNA origami nanostructures. The team includes Professor Do-Nyun Kim's research team from the Department of Mechanical Engineering at The College.....»»
DNA Topoisomerase insights hold potential for drug discovery and plant protection
Insights into the function of DNA Topoisomerase VI (Topo VI) may provide a springboard for drug discovery and crop protection......»»
A Submersible Uncovered Secret Structures. Then, It Vanished Under Antarctic Waters.
A Submersible Uncovered Secret Structures. Then, It Vanished Under Antarctic Waters......»»
This new Google Chrome feature could make the internet more pleasant
Google Chrome is in the works to make tipping your favorite sites easier using Web Monetization to send micro payments. Here's how it works......»»
Newly-discovered star could provide new insights into the evolution of stars
A new study published in The Astrophysical Journal, led by Assistant Professor of Astronomy Rana Ezzeddine and UF alumnus Jeremy Kowkabany, with collaborators, reports the discovery of a star that challenges astronomers' understanding of star evoluti.....»»
Broadway embraces particle physics with musical about Higgs boson discovery
The 2013 documentary Particle Fever is being turned into a Broadway musical. A collision between subatomic particles in the Large Hadron Collider's CMS detector. (credit: Research.gov) Particle physics is poised to hit t.....»»
"Miseries of the Balkhash": Fears for Kazakhstan"s magical lake
Seen from the sky, with its turquoise waters stretching out into the desert expanses in the shape of a crescent, you can see why they call Lake Balkhash the "pearl of Kazakhstan"......»»
Scientists discover highest-energy gamma-ray line in the universe
A research group led by the Institute of High Energy Physics (IHEP) of the Chinese Academy of Sciences (CAS) report the discovery of a gamma-ray line up to 37 million electron-volts from an extremely bright gamma-ray burst, which represents the highe.....»»
After AI, quantum computing eyes its "Sputnik" moment
Quantum computing promises society-changing breakthroughs in drug development and tackling climate change, and on an unassuming English high street, the race to unleash the latest tech revolution is gathering pace......»»
Fishing disrupts squaretail grouper mating behavior, study finds
Populations of squaretail grouper face an uncertain future as new research shows fishing that targets their spawning sites is causing males to be repeatedly scared away from their territories during their short mating meetups......»»
Researchers reveal atomic-scale details of catalysts" active sites
The chemical and energy industries depend upon catalysts to drive the reactions used to create their products. Many important reactions use heterogeneous catalysts—meaning that the catalysts are in a different phase of matter than the substances th.....»»
Novel machine learning-based cluster analysis method that leverages target material property
In materials science, substances are often classified based on defining factors such as their elemental composition or crystalline structure. This classification is crucial for advances in materials discovery, as it allows researchers to identify pro.....»»