TSUBAME supercomputer predicts cell-membrane permeability of cyclic peptides
Scientists at Tokyo Institute of Technology have developed a computational method based on large-scale molecular dynamics simulations to predict the cell-membrane permeability of cyclic peptides using a supercomputer. Their protocol has exhibited pro.....»»
Scientists identify structural basis of stitched-together protein complexes that recycle most proteins in cells
Scientists at Sanford Burnham Prebys have developed a clearer picture of how crucial machinery in the human cell's recycling process for obsolete and misshapen proteins—known as proteasomes—are formed......»»
Shedding light on a decades-old protein sorting mystery
Christian de Caestecker, a Ph.D. student in the lab of Ian Macara, Louise B. McGavock Professor and chair of the Department of Cell and Developmental Biology, has proposed and validated a mechanism that addresses a decades-old mystery surrounding epi.....»»
Model predicts 2024 tick cases in Australian pets
For the first time, University of Queensland scientists have been able to make a prediction about the severity of upcoming tick seasons to help vet surgeries and pet owners prepare......»»
Biologists sequence proteins by pulling them through nanopores
A team of chemical biologists at the University of Washington, working with colleagues at Oxford Nanopore Technologies, has developed a protein sequencing process that involves pulling proteins through nanopores in a lipid membrane. Their paper is pu.....»»
Semimetal-induced covalency achieves high-efficiency electrocatalysis for platinum intermetallic compounds
Compared with other types of batteries, proton exchange membrane fuel cells have the advantages of high discharge power and no pollution, which is also an important carrier for hydrogen energy conversion and utilization. Platinum intermetallic compou.....»»
Bacterial "flipping" allows genes to assume different forms
Imagine being one cartwheel away from changing your appearance. One flip, and your brunette locks are platinum blond. That's not too far from what happens in some prokaryotes, or single-cell organisms, such as bacteria, that undergo something called.....»»
GM, Piston plot hydrogen fuel cell factory in Detroit
GM and Piston Automotive are plotting a hydrogen fuel cell factory in Detroit, GM's first standalone plant for fuel cell production......»»
Cryo-ET study provides viral close-up of HTLV-1, the "overlooked cousin of HIV"
In collaboration with the University of Minnesota and Cornell University, Martin Obr and Florian Schur from the Institute of Science and Technology Austria (ISTA) provide new details into the architecture of HTLV-1 (Human T-cell Leukemia Virus Type 1.....»»
Q&A: What"s behind the ban on cell phones in K-12 schools?
This school year, many of the nation's adolescents and teens are sitting in class without the device that can sometimes feel like an added appendage: their smartphones......»»
Researchers uncover key insights into cholesterol"s structure in cell membranes
A new study by Rice University researchers led by Jason Hafner could open new pathways for understanding how cholesterol influences cell membranes and their receptors, paving the way for future research on diseases linked to membrane organization. Th.....»»
New progenitor cell type discovered, may aid in tissue repair and generation
A team of SAHMRI scientists has discovered a completely new type of cell that has the potential to enhance the future of tissue repair and generation......»»
AI tools help uncover enzyme mechanisms for lasso peptides
Lasso peptides are natural products made by bacteria. Their unusual lasso shape endows them with remarkable stability, protecting them from extreme conditions. In a new study, published in Nature Chemical Biology, researchers have constructed and tes.....»»
Researchers identify novel endocytic recycling mechanism with "kiss-and-run" membrane fusion
Endocytosis and recycling control the uptake and retrieval of various materials in eukaryotic cells. Mammalian cells have developed several recycling routes, including the relatively extensively studied "fast" and "slow" tubulovesicular recycling pat.....»»
Double-edged STING: A new pathway involved in aging
A protein called STING, previously shown to control a pathway that contributes to antiviral signaling, also plays an important role in cellular stress clearance and cell survival, according to a new paper published in Molecular Cell......»»
Don"t overlook microorganisms" role in planet health, scientists warn
The tiniest and oldest creatures on—and in—Earth have a huge role in achieving a sustainable future for the planet, an international team of scientists, including faculty researchers from The Ohio State University, asserts in a new Cell article p.....»»
A $1 billion solar cell factory is coming to this U.S. state — and hundreds of new jobs are on the way
A $1 billion solar cell factory is coming to this U.S. state — and hundreds of new jobs are on the way.....»»
Research predicts rise in tropical hydraulic failure
Hydraulic failure in tropical environments is expected to increase, according to new research published in New Phytologist. As weather patterns change and temperatures rise, plants will need to adapt in order to survive. Hydraulic failure occurs when.....»»
Gene-based model predicts when Japan"s cherry buds awake from dormancy
Japan in spring is famous for its cherry blossoms, or sakura, which begin flowering in the southern region of Kyushu and blaze upwards to the remote north of Hokkaido. The most abundant cherry tree cultivar, Somei Yoshino, is the iconic symbol of spr.....»»
Meet the Advocates and Researchers Revolutionizing Sickle Cell Care
These sickle cell researchers and advocates are driving change from labs to global stages, transforming lives in the process......»»
New Sickle Cell Treatments Reach Patients after Years of Effort
The FDA recently approved three sickle cell drugs, and dozens more are in development.....»»