TSUBAME supercomputer predicts cell-membrane permeability of cyclic peptides
Scientists at Tokyo Institute of Technology have developed a computational method based on large-scale molecular dynamics simulations to predict the cell-membrane permeability of cyclic peptides using a supercomputer. Their protocol has exhibited pro.....»»
Researchers Seek New Solutions to Ease Sickle Cell’s Extreme Pain
Sickle cell disease causes severe pain that’s hard to treat, but researchers are finding new ways to offer relief.....»»
A Global Initiative to Advance Sickle Cell Research Could Benefit Millions
Increased funding and new public health policies for sickle cell research are needed to ease the burden on low-income nations and improve patient care.....»»
People Living with Sickle Cell Disease Share Their Experiences
Life expectancy for people with sickle cell in the U.S. has increased to about 50 years, but some people with the disease still face stigma and other barriers in health care.....»»
New Hope for Treating People with Sickle Cell Disease
Improving sickle cell care by expanding treatment options, advancing new therapies and amplifying the voices of people with the disease.....»»
New Sickle Cell Treatments Highlight the Power of Patient Perspectives
Illuminating the experience of people living with sickle cell could improve patients’ lives and enhance all of medicine.....»»
Going Back to the Moon, Researching Chickadee Hybrids and Understanding Addiction
This month’s issue covers the reasons it’s so hard to go back to the moon, the science of empathy and new advances in treating sickle cell disease.....»»
What Is Sickle Cell Disease?
You have around 35 trillion red blood cells moving around your body at all times. Typically they are rounded and flexible. What happens when they aren’t?.....»»
Scientists decipher the energy patterns in our cells
Our cells harness energy for essential functions such as division, wound healing, and our immune response to diseases including cancer. But until now, the mechanics of how that energy affects cell behavior—and how this relates to health outcomes—.....»»
Optogenetic control reveals collective cell behavior
New research led by the Institute for Bioengineering of Catalonia (IBEC) has studied the migratory movement of groups of cells using light control. The results show that there is no leader cell that directs the collective movement, as previously thou.....»»
Scientists discover how TGF-Beta sends its message even while tethered to the cell membrane
For years, scientists have thought that TGF-Beta, a signaling protein that holds sway over an astonishing array of cellular processes from embryonic development to cancer, could only do its work once it escaped a lasso-like "straitjacket.".....»»
Modified nano-sized cell particles found to boost cancer immunotherapy, reduce side effects
Immunotherapy is a type of cancer treatment that uses the body's own immune system to help fight cancer. This is by stimulating the immune response to recognize and attack cancer cells more effectively. The treatment involves using substances that bo.....»»
Beyond displays: Liquid crystals in motion mimic biological systems
Liquid crystals are all around us, from cell phone screens and video game consoles to car dashboards and medical devices. Run an electric current through liquid crystal displays (LCDs) and they generate colors, thanks to the unique properties of thes.....»»
Researchers develop novel covalent organic frameworks for precise cancer treatment delivery
A team of researchers at NYU Abu Dhabi (NYUAD), led by Program Head of Chemistry Ali Trabolsi, have developed nanoscale covalent organic frameworks (nCOFs), crystalline organic polymers that have been modified with peptides to treat the most aggressi.....»»
Tubular scaffolds boost stem cell-driven bone regeneration in skull defects
Scientists from Sun Yat-sen University's School of Biomedical Engineering have developed tubular scaffolds made from electrospun membranes, which significantly enhance bone regeneration in critical skull defects......»»
Catalyzing environmental cleanup: A highly active and selective molecular catalyst and electrified membrane
Some chemicals create environmental problems; others, fortunately, can help clean them up. Chemists from Yale University and their colleagues have developed an electrochemical catalyst and membrane that offers an efficient and sustainable way to trea.....»»
Elucidating the mechanism underlying de novo membrane formation during gametogenesis
Researchers at University of Tsukuba have meticulously examined the gametogenesis of budding yeast, a process involving meiosis and spore formation, using live imaging techniques. Their findings reveal that during sporulation, the endoplasmic reticul.....»»
Battery EVs vs fuel-cell EVs: Could hydrogen power your next car?
While battery EVs have a huge lead, there are still plenty of proponents of hydrogen EVs, or fuel-cell EVs. Could FCEVs actually take over? Well, probably not......»»
Researchers examine protein arrangement in cell membrane that triggers programmed cell death
How can molecular structures be analyzed when the resolution of the techniques available is not sufficient? Researchers from the fields of physics, chemistry and medicine at Heinrich Heine University Düsseldorf (HHU) have combined and further develo.....»»
Uncovering the unique roles of Exportin-5 in RNA export within Drosophila cells
Eukaryotic cells are complex biological units, each with multiple membrane-bound compartments. These cells use specialized mechanisms to export biomolecules from their synthesis site to where they function......»»
Studying fungi"s "weak link" to fight global rise in deadly fungal infections
A group of scientists at the Department of Energy's Oak Ridge National Laboratory have conducted neutron scattering research to reveal key information about fungus cell membranes that could aid in developing new antifungal treatments......»»