Swimming microrobots deliver cancer-fighting drugs to metastatic lung tumors in mice
Engineers at the University of California San Diego have developed microscopic robots, known as microrobots, capable of swimming through the lungs to deliver cancer-fighting medication directly to metastatic tumors. This approach has shown promise in.....»»
Ultrasound beam triggers "nanodroplets" to deliver drugs at exactly the right spot
Conventional drug delivery is often like cracking a nut with a sledgehammer. Whether the drug is swallowed, injected, inhaled, or absorbed through the skin, it ultimately diffuses to most parts of the body, including those where it isn't needed—or.....»»
Lung-targeting lipid nanoparticles with CRISPR components successfully treat cystic fibrosis mouse models
A team of medical researchers from the University of Texas Southwestern Medical Center, Case Western Reserve University School of Medicine and ReCode Therapeutics has developed a way to send gene-editing tools to the lungs to repair the faulty gene a.....»»
Drugmaker to testify on why weight-loss drugs cost 15x more in the US
Bernie Sanders cancels subpoena vote. Enlarge / Lars Fruergaard Jorgensen, chief executive officer Novo Nordisk A/S, during an interview at the company's headquarters in Bagsvaerd, Denmark, on Monday, June 12, 2023. (credit: Get.....»»
Some CRISPR screens may be missing cancer drug targets
CRISPR/Cas9 gene editing has made possible a multitude of biomedical experiments, including studies that systematically turn off genes in cancer cells to look for ones that the cancer cells heavily depend on to survive and grow. These genes, or "canc.....»»
Research says high energy fire influences prescribed burn effectiveness
Fighting woody plant encroachment with prescribed burns may be more effective than land managers previously thought......»»
Improving the ability of phototherapy to stimulate the systemic immune response to cancer
Phototherapy is a safe and effective method for tumor treatment, including photothermal therapy (PTT) and photodynamic therapy (PDT). PTT refers to the use of laser to activate photothermal conversion agents and use high temperature to kill tumor cel.....»»
PHP command injection flaw exploited to deliver ransomware (CVE-2024-4577)
An OS command injection vulnerability in Windows-based PHP (CVE-2024-4577) in CGI mode is being exploited by the TellYouThePass ransomware gang. Imperva says the attacks started on June 8, two days after the PHP development team pushed out fixes, and.....»»
IV infusion enables editing of the cystic fibrosis gene in lung stem cells
Approach relies on lipid capsules like those in the mRNA vaccines. Enlarge (credit: DrAfter123) The development of gene editing tools, which enable the specific targeting and correction of mutations, hold the promise of.....»»
SCOTUS rejects challenge to abortion pill for lack of standing
The anti-abortion defendants are not injured by the FDA's actions on mifepristone. Enlarge / Mifepristone (Mifeprex) and misoprostol, the two drugs used in a medication abortion, are seen at the Women's Reproductive Clinic, which.....»»
New dart launcher may be a better way to inject animals with drugs
A new type of dart launcher has been developed as a safer and more cost-effective alternative to firearms or air guns to inject animals with drugs or tracking chips......»»
Researchers discover honeybees can detect lung cancer
Michigan State University researchers have discovered that honeybees can detect biomarkers or chemical concentrations associated with lung cancer in human breath. The researchers have also shown that the honeybees can distinguish between different lu.....»»
Researchers develop new electrochemical biosensor for cancer prognosis
Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University report in Biosensors and Bioelectronics: X a novel approach for detecting a particular biomolecule associated with several diseases. The results show good sensitivity and s.....»»
Quirky circling behavior in mice informs research on humans in space
During the Rodent Research-1 (RR-1) mission flown to the ISS in 2014, videos that were taken to observe the mice revealed an unusual behavior that researchers are still working to understand. Young (16-week-old) but not old (32-week-old) mice engaged.....»»
Swimming microrobots deliver cancer-fighting drugs to metastatic lung tumors in mice
Engineers at the University of California San Diego have developed microscopic robots, known as microrobots, capable of swimming through the lungs to deliver cancer-fighting medication directly to metastatic tumors. This approach has shown promise in.....»»
"Synthetic" cell shown to follow chemical directions and change shape, a vital biological function
In a feat aimed at understanding how cells move and creating new ways to shuttle drugs through the body, scientists at Johns Hopkins Medicine say they have built a minimal synthetic cell that follows an external chemical cue and demonstrates a govern.....»»
Scientists propose novel AI approach for lipid nanoparticles screening in mRNA delivery
The targeted treatment of pan-cancer by messenger RNA (mRNA) vaccine is a hot topic in drug research. A key challenge in mRNA design is the construction of delivery systems called lipid nanoparticles (LNPs), which serve as carriers to deliver mRNA th.....»»
Elephants may refer to each other by name
The animals seem to respond more actively to calls that include their "name." Enlarge (credit: Buena Vista Images) Lots of animals communicate with each other, from tiny mice to enormous whales. But none of those forms o.....»»
AI system learns to speak the language of cancer to enable improved diagnosis
A computer system which harnesses the power of AI to learn the language of cancer is capable of spotting the signs of the disease in biological samples with remarkable accuracy, its developers say......»»
Nanoparticles reprogram mouse immune systems to cope with allergens
Two doses of allergen-encapsulating nanoparticles delivered intravenously prevented anaphylaxis during a food allergy test in mice, according to a study led by University of Michigan researchers......»»
Lung organoids reveal how pathogens infect human lung tissue
How do pathogens invade the lungs? Using human lung microtissues, a team at the Biozentrum of the University of Basel has uncovered the strategy used by a dangerous pathogen. The bacterium targets specific lung cells and has developed a sophisticated.....»»