Swimming microrobots deliver cancer-fighting drugs to metastatic lung tumors in mice
Engineers at the University of California San Diego have developed microscopic robots, known as microrobots, capable of swimming through the lungs to deliver cancer-fighting medication directly to metastatic tumors. This approach has shown promise in.....»»
Radioactive drugs strike cancer with precision
Tumor-seeking radiopharmaceuticals promise targeted treatments with fewer side effects. Enlarge / Pharma interest and investment in radiotherapy drugs is heating up. (credit: Knowable Magazine) On a Wednesday morning in.....»»
Scientists use heart and lung model to calculate potential health threats facing future space tourists in microgravity
Space exploration has always captivated our imagination, offering the promise of discovering new worlds and pushing the boundaries of human capability. As commercial space travel becomes more accessible, individuals with various underlying health con.....»»
A simple, fast, and versatile method for selective bromination of indole alkaloids
The development of drugs through chemical modifications of naturally occurring indole alkaloids has emerged as an attractive research area. However, due to their reactivity, the selective functionalization at the C5 position of the indole ring has be.....»»
Scientists devise algorithm to engineer improved enzymes
Scientists have prototyped a new method for "rationally engineering" enzymes to deliver improved performance. They have devised an algorithm, which takes into account an enzyme's evolutionary history, to flag where mutations could be introduced with.....»»
Study reveals molecular mechanisms of somatostatin receptor 5 activation by neuropeptides and drugs
Somatostatin receptors (SSTRs) constitute a crucial family of G protein-coupled receptors (GPCRs) that play pivotal roles in regulating hormone secretion and inhibiting tumor growth......»»
Old drugs new tricks—novel approach shows "enormous potential" for rapid antibiotic discovery
An innovative project to re-purpose existing drugs for their potential as antibiotics has uncovered a highly promising candidate with a potent and unique way of killing drug resistant bacteria......»»
These amazing projectors deliver incredible images and stunning sound
Discover the projector that "looks better and sounds perfect".....»»
Clever macOS malware delivery campaign targets cryptocurrency users
Cryptocurrency users are being targeted with legitimate-looking but fake apps that deliver information-stealing malware instead, Recorded Future’s researchers are warning. The threat actor behind this complex scheme is going after both Windows.....»»
Observations explore stellar content of nearby young open cluster Berkeley 59
Astronomers from India and Thailand have observed a young nearby open cluster known as Berkeley 59. Results of the observational campaign, published June 12 on the pre-print server arXiv, deliver essential information regarding low-mass stellar and s.....»»
Ultrasound beam triggers "nanodroplets" to deliver drugs at exactly the right spot
Conventional drug delivery is often like cracking a nut with a sledgehammer. Whether the drug is swallowed, injected, inhaled, or absorbed through the skin, it ultimately diffuses to most parts of the body, including those where it isn't needed—or.....»»
Lung-targeting lipid nanoparticles with CRISPR components successfully treat cystic fibrosis mouse models
A team of medical researchers from the University of Texas Southwestern Medical Center, Case Western Reserve University School of Medicine and ReCode Therapeutics has developed a way to send gene-editing tools to the lungs to repair the faulty gene a.....»»
Drugmaker to testify on why weight-loss drugs cost 15x more in the US
Bernie Sanders cancels subpoena vote. Enlarge / Lars Fruergaard Jorgensen, chief executive officer Novo Nordisk A/S, during an interview at the company's headquarters in Bagsvaerd, Denmark, on Monday, June 12, 2023. (credit: Get.....»»
Some CRISPR screens may be missing cancer drug targets
CRISPR/Cas9 gene editing has made possible a multitude of biomedical experiments, including studies that systematically turn off genes in cancer cells to look for ones that the cancer cells heavily depend on to survive and grow. These genes, or "canc.....»»
Research says high energy fire influences prescribed burn effectiveness
Fighting woody plant encroachment with prescribed burns may be more effective than land managers previously thought......»»
Improving the ability of phototherapy to stimulate the systemic immune response to cancer
Phototherapy is a safe and effective method for tumor treatment, including photothermal therapy (PTT) and photodynamic therapy (PDT). PTT refers to the use of laser to activate photothermal conversion agents and use high temperature to kill tumor cel.....»»
PHP command injection flaw exploited to deliver ransomware (CVE-2024-4577)
An OS command injection vulnerability in Windows-based PHP (CVE-2024-4577) in CGI mode is being exploited by the TellYouThePass ransomware gang. Imperva says the attacks started on June 8, two days after the PHP development team pushed out fixes, and.....»»
IV infusion enables editing of the cystic fibrosis gene in lung stem cells
Approach relies on lipid capsules like those in the mRNA vaccines. Enlarge (credit: DrAfter123) The development of gene editing tools, which enable the specific targeting and correction of mutations, hold the promise of.....»»
SCOTUS rejects challenge to abortion pill for lack of standing
The anti-abortion defendants are not injured by the FDA's actions on mifepristone. Enlarge / Mifepristone (Mifeprex) and misoprostol, the two drugs used in a medication abortion, are seen at the Women's Reproductive Clinic, which.....»»
New dart launcher may be a better way to inject animals with drugs
A new type of dart launcher has been developed as a safer and more cost-effective alternative to firearms or air guns to inject animals with drugs or tracking chips......»»
Researchers discover honeybees can detect lung cancer
Michigan State University researchers have discovered that honeybees can detect biomarkers or chemical concentrations associated with lung cancer in human breath. The researchers have also shown that the honeybees can distinguish between different lu.....»»