Supersize the cell: Unlocking genome secrets through expansion microscopy
The ability to turn genes on or off is fundamental to the diversity we see in cells, in individuals, and even in terms of health and disease. This process, known as gene transcription, involves converting the information stored in our DNA into a "car.....»»
Scientists modify citrus pectin with induced electric field
Pectin, a natural and nontoxic acidic polysaccharide, is widely found in the primary cell wall and inner layer of terrestrial higher plants. The main domains of pectin are homogalacturonan and rhamnogalacturonan I, which contribute to the complexity.....»»
Scientists unlock the secrets of how a key protein converts DNA into RNA
Researchers at the Department of Energy's SLAC National Accelerator Laboratory have uncovered new insights into the fundamental mechanisms of RNA polymerase II (Pol II), the protein responsible for transcribing DNA into RNA. Their study shows how the.....»»
Bacterial defense strategy has potential application in genome editing
Scientists who have described in a new study the step-by-step details of a bacterial defense strategy see the mechanism as a promising platform for development of a new genome-editing method......»»
New knowledge about cell receptors paves the way for future drugs against intestinal tumors
A new study from Karolinska Institutet published in Nature Communications provides valuable insights into the activation of receptors on the cell surface. The knowledge could lead to new targeted therapies and drugs against intestinal tumors, among o.....»»
Researchers map 50,000 of DNA"s mysterious "knots" in the human genome
Researchers have mapped 50,000 of DNA's mysterious "knots" in the human genome. The innovative study of DNA's hidden structures may open up new approaches for treatment and diagnosis of diseases, including cancer......»»
"Silent" mutations found to have repercussions beyond their own gene
Genetic disorders—like cystic fibrosis and Huntington's disease—are considered incurable, with gene mutations occurring in essentially every cell of the body. Gene mutations occur when one nucleotide in a codon is switched. In non-synonymous muta.....»»
Light microscopy study reveals molecular density changes during mitotic chromosome condensation
A team of scientists studying cell division developed a special light microscopy system and used it to analyze the molecular density of cellular environments. Their results provide a novel insight into mitotic chromosome condensation in living human.....»»
Discovery explains the chemistry behind the cell"s energy molecule
An international research team led by Professor Magnus Wolf-Watz at Umeå University has discovered how the magnesium atom directs the chemistry that catalyzes the production of the energy molecule ATP in a cell. The study is published in the journal.....»»
Maintaining company confidentiality simultaneously hurts and helps workers" well-being
A hush has fallen over the workplace. At tech startups and banks, in doctors' offices and law firms, workers are increasingly being asked to keep secrets. These aren't personal confidences but organizational secrets about clients, proprietary technol.....»»
Expel partners with Wiz to enhance security for cloud environments
Expel announced a new strategic partnership with Wiz, a cloud-native application protection platform (CNAPP). The partnership provides an integration offering MDR for Wiz toxic risk combinations (including vulnerabilities, secrets, malware, and threa.....»»
Study links fear of conflict to population changes in Neolithic Europe
Since the end of the last Ice Age, growth of the human population has been far from uniform, marked instead by periods of rapid expansion followed by sharp declines. The reasons behind these fluctuations remain only partially understood......»»
Toyota, BMW to upgrade fuel cell alliance, report says
BMW and Toyota plan to sign a memorandum of understanding for the partnership next week, with an official announcement set for Sept. 5, Nikkei Asia reported......»»
Kamikaze termites protect their colony with the help of a special enzyme whose secrets have now been uncovered
Researchers from the Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, in cooperation with colleagues from the Faculty of Tropical AgriScience of the Czech University of Life Sciences in Prague, are unraveling the myst.....»»
Dissecting caspase-2-mediated cell death: From intrinsic PIDDosome activation to chemical modulation
Caspase-2, an initiator caspase, plays a critical role in programmed cell death in response to certain cellular stresses. Its activation is facilitated by the PIDDosome, a multi-protein complex that assembles under conditions of genotoxic stress. Des.....»»
Study reveals bioactive power of a natural spearmint compound against weeds
A recent study reveals the natural compound (-)-carvone in spearmint as a potent and sustainable alternative to chemical herbicides. This research demonstrates how (-)-carvone targets and degrades microtubules in weeds, inducing cell death and inhibi.....»»
Researchers investigate cell-free DNA as early sepsis marker in foals
It's hard to be a horse. It's especially hard to be a newborn foal, dropped into a world of microbes and bacteria with your sole initial defense against devastating infections being the antibodies you get from your mother's milk, or colostrum. Resear.....»»
Tomato ripening study highlights cell wall component interactions
Tomato fruit ripening involves intricate biochemical and structural changes, particularly within the cell wall, which are vital for the fruit's final texture and quality. These changes include modifications in polysaccharides and proteins, but the sp.....»»
Unlocking crop yield potential: New modeling approach for sustainable agriculture
Predicting crop yields is a significant challenge in modern agriculture, especially under fluctuating environmental conditions. With the escalating demand for sustainable food production, understanding the complex interplay between environmental fact.....»»
Mapping the sex life of malaria parasites at single cell resolution reveals genetics underlying transmission
Malaria is caused by a eukaryotic microbe of the Plasmodium genus, and is responsible for more deaths than all other parasitic diseases combined. In order to transmit from the human host to the mosquito vector, the parasite has to differentiate into.....»»
Kingdom Hearts 4: everything we know so far
This sequel's full picture isn't clear as of yet, but we've done our best to unlock all the secrets we can and share everything we know about Kingdom Hearts 4......»»