"Silent" mutations found to have repercussions beyond their own gene
Genetic disorders—like cystic fibrosis and Huntington's disease—are considered incurable, with gene mutations occurring in essentially every cell of the body. Gene mutations occur when one nucleotide in a codon is switched. In non-synonymous muta.....»»
Study maps bed bugs" genomes in unprecedented detail to find out why they just won"t die
Scientists mapped near-gap-free and near-error-free genomes of a susceptible bed bug strain and a superstrain around 20,000 times more insecticide-resistant, offering the broadest look yet at the full scope of their resistance mutations......»»
Studies pin down exactly when humans and Neanderthals swapped DNA
We may owe our tiny sliver of Neanderthal DNA to just a couple of hundred Neanderthals. Two recent studies suggest that the gene flow (as the young people call it these days) betw.....»»
Apple issues updates for iPadOS 17, macOS Ventura, Sonoma
As part of Apple's operating system update releases, it has also brought out updates for older iPadOS and macOS generations for the public to install.An iMac running an older macOS versionWhile the main focus of software updates is on the latest gene.....»»
Computer modeling shows close encounters between distant DNA regions cause bursts of gene activity
Researchers at Kyushu University have revealed how spatial distance between specific regions of DNA is linked to bursts of gene activity. Using advanced cell imaging techniques and computer modeling, the researchers showed that the folding and moveme.....»»
Nanoparticle-mediated gene therapy fixes major cause of stillbirth and premature birth in guinea pig model
The life of billions of people inhabiting Earth is owed to a temporary organ that supported and nourished them in a mother's womb. The placenta, or afterbirth, is considered sacred by some cultures, its pivotal role in pregnancy recognized as far bac.....»»
Scientists identify mutation that could facilitate H5N1 bird flu virus infection and potential transmission in humans
Avian influenza viruses typically require several mutations to adapt and spread among humans, but what happens when just one change can increase the risk of becoming a pandemic virus?.....»»
Historical outbreaks of coffee wilt disease linked to gene transfer from another fungus
The fungus that causes coffee wilt disease repeatedly took up segments of DNA from a related fungal pathogen, which contributed to successive outbreaks of the disease. Lily Peck of Imperial College London, U.K., reports these new findings in a study.....»»
Gene editing and plant domestication essential to protect food supplies in a worsening climate, scientists say
We all need to eat, but the impact of the climate crisis on our crops is throwing the world's food supply into question. Modern crops, domesticated for high food yields and ease of harvesting, lack the genetic resources to respond to the climate cris.....»»
Poplar tree study discovers a photosynthesis gene that boosts plant height
A team of scientists have identified a gene in poplar trees that enhances photosynthesis and can boost tree height. The study, "An orphan gene BOOSTER enhances photosynthetic efficiency and plant productivity," is published in Developmental Cell, and.....»»
Decoding protein interactions to better understand how mutations contribute to disease
Investigating how proteins interact is key to understanding how cells work and communicate. In a new study published in Nature Communications, FMI researchers have provided key insights into how protein interactions are governed and how mutations inf.....»»
Seeing is believing: Leveraging defining morphological features for accurate selection of brain organoids
By combining morphological and single-cell level gene expression analyses, a team of researchers led by Professor Jun Takahashi in the Department of Clinical Application at Kyoto University has established a new non-destructive system to select high-.....»»
Decoding the structure of nano "gene ferries" to advance RNA drugs
LMU researchers have investigated how cationic polymers organize on a molecular level when transporting RNA drugs......»»
Gene regulation study reports surprising results: Extensive regions of DNA belong to multiple gene switches
Some sequences in the genome cause genes to be switched on or off. Until now, each of these gene switches, or so-called enhancers, was thought to have its own place on the DNA. Different enhancers are therefore separated from each other, even if they.....»»
"e-Drive": New gene drive reverses insecticide resistance in pests... then disappears
Insecticides have been used for centuries to counteract widespread pest damage to valuable food crops. Eventually, over time, beetles, moths, flies and other insects develop genetic mutations that render the insecticide chemicals ineffective......»»
Gene expression shifts help explain how a shrew changes brain size to match the seasons
New research shows how the Eurasian common shrew (Sorex araneus) changes its brain and bodily size throughout the year. The study, published online in eLife, reveals how changes in gene expression enable these small mammals to shrink their brain in.....»»
Cas9-PE system achieves precise editing and site-specific random mutation in rice
Achieving the aggregation of different mutation types at multiple genomic loci and generating transgene-free plants in the T0 generation is an important goal in crop breeding. Although prime editing (PE), as the latest precise gene editing technology.....»»
Mathematical modeling study demonstrates gene drives could boost malaria control when added to intervention package
The Target Malaria UK modeling team at Imperial College London has published their latest study in Nature Communications, titled "The potential of gene drives in malaria vector species to control malaria in African environments.".....»»
Algorithm predicts DNA methylation in ancient specimens, providing insight into human evolution
Research published in Nature Ecology & Evolution introduces a novel method for inferring DNA methylation patterns in non-skeletal tissues from ancient specimens, providing new insights into human evolution. As DNA methylation is a key marker of gene.....»»
Devs investigating why their games look bad on the PS5 Pro
Silent Hill 2 remake, Jedi Survivor, and other games are having visual and performance issues on the PS5 Pro, even with the enhancements......»»
Electromagnetic Symphony: Explore the EMF Universe
Make EMF radiation audible and listen in to the silent backbone of our electronics society with an EMF audio amplifier. The post Electromagnetic Symphony: Explore the EMF Universe appeared first on Make: DIY Projects and Ideas for Makers......»»