Structural changes in snap-frozen proteins
Researchers have succeeded in ultra-fast freezing proteins after a precisely defined period of time. They were able to follow structural changes on the microsecond time scale and with sub-nanometer precision. Owing to its high spatial and temporal re.....»»
Filament structure found to activate and regulate CRISPR-Cas "protein scissors"
CRISPR-Cas systems help to protect bacteria from viruses. Several different types of CRISPR-Cas defense systems are found in bacteria, which differ in their composition and functions. Among them, the most studied proteins today are Cas9 and Cas12, al.....»»
Developing novel chiral capsule tools for advanced optical technologies
Chirality is an essential property in biology; the molecular building blocks of some of the most important biological structures, including DNA and proteins, are chiral. When a molecule is said to be chiral, it means that it is distinguishable from i.....»»
Planning a drug"s route in the body with synthetic chemistry
Researchers at the RIKEN Cluster for Pioneering Research (CPR) have developed technology that can alter, within the body, the recognized identity of proteins......»»
Research provides new insights into role of mechanical forces in gene expression
The genome inside each of our cells is modeled by tension and torsion—due in part to the activity of proteins that compact, loop, wrap and untwist DNA—but scientists know little about how those forces affect the transcription of genes......»»
Seeing double: Designing drugs that target "twin" cancer proteins
Some proteins in the human body are easy to block with a drug; they have an obvious spot in their structure where a drug can fit, like a key in a lock. But other proteins are more difficult to target, with no clear drug-binding sites......»»
Scientists identify structural basis of stitched-together protein complexes that recycle most proteins in cells
Scientists at Sanford Burnham Prebys have developed a clearer picture of how crucial machinery in the human cell's recycling process for obsolete and misshapen proteins—known as proteasomes—are formed......»»
Study offers new explanation for Siberia"s permafrost craters
Mysterious craters that first appeared in the Siberian permafrost a decade ago were caused by climate change-driven pressure changes that explosively released methane frozen underground, a new study reports. The research offers a fresh take on the or.....»»
Dead coral skeletons hinder reef regeneration by sheltering seaweed
The structural complexity of coral reefs creates a vibrant underwater city populated by a diverse assortment of characters. Ironically, this same complexity can impede coral recovery after disturbances......»»
AI trained on evolution"s playbook develops proteins that spur drug and scientific discovery
A new artificial intelligence model developed by researchers at The University of Texas at Austin paves the way for more effective and less toxic treatments and new preventive strategies in medicine. The AI model informs the design of protein-based t.....»»
Biologists sequence proteins by pulling them through nanopores
A team of chemical biologists at the University of Washington, working with colleagues at Oxford Nanopore Technologies, has developed a protein sequencing process that involves pulling proteins through nanopores in a lipid membrane. Their paper is pu.....»»
Existence of an Earth-like planet around a dead sun offers hope for our planet"s ultimate survival
The discovery of an Earth-like planet 4,000 light years away in the Milky Way galaxy provides a preview of one possible fate for our planet billions of years in the future, when the sun has turned into a white dwarf, and a blasted and frozen Earth ha.....»»
Frozen in time: Rock fossils hint at Mars"s ancient climate
Long ago, flowing wind and water shaped Mars's malleable sand and sediment into dunes, ripples and other landscape patterns, called bedforms. Over billions of years, some of these landforms hardened into rock—scientists then call them paleo-bedform.....»»
Researcher develops low-sugar ice cream with smooth texture
Wageningen researcher Qi Wang has developed a new variant of low-sugar ice cream that mimics the texture and melting properties of traditional ice cream. By replacing half of the sugar with broken-down proteins or the sweetener xylitol, she succeeded.....»»
Strategies for maximizing recombinant protein production in tobacco plants
Plant molecular farming (PMF) is a modern, sophisticated technology that utilizes plants' biosynthetic machinery to synthesize a plethora of recombinant proteins, including industrial and therapeutic enzymes. It has several advantages over traditiona.....»»
Answers company recalls raw dog food due to salmonella, listeria threat
A raw diet pet food company is recalling cartons of frozen beef and chicken dog food that could be tainted with salmonella or listeria germs......»»
Naked mole-rat found to have lost infection-resistant proteins
Scientists have found that the naked mole-rat—an underground rodent that lives up to 40 years—has lost a number of CD1 functional genes. The CD1 gene family in mammals is responsible for protein synthesis that protects the body against infectious.....»»
Razer just opened the floodgates for its ‘cheating’ Snap Tap feature
Razer is rolling out an update that massively expands support for its competitive Snap Tap feature, including to Razer Blade laptops......»»
Chemists discover new ways in which single-celled organisms organize their DNA
It has only recently been discovered that single-celled organisms (bacteria and archaea) also have histones—proteins that structure DNA. Now, Leiden Ph.D. candidate Samuel Schwab has found that the histones in these organisms are much more diverse.....»»
From chaos to order: Proteins can re-structure themselves to create important substances
The protein "MIPS" changes its internal structure when it becomes active. Its disordered active center becomes a defined structure with special functions. The protein plays a key role in the production of inositol, which is also known as vitamin B8,.....»»
Man dies in freak accident involving frozen hamburgers: "Difficult to hear"
Man dies in freak accident involving frozen hamburgers: "Difficult to hear".....»»