Structural changes in snap-frozen proteins
Researchers have succeeded in ultra-fast freezing proteins after a precisely defined period of time. They were able to follow structural changes on the microsecond time scale and with sub-nanometer precision. Owing to its high spatial and temporal re.....»»
Glowing proteins enable real-time, 3-D study of essential enzymes
Working in organoid models, researchers at University of California San Diego School of Medicine have developed a new tool to study protein-kinase C (PKC) enzymes, which play a critical role in cell growth, differentiation and survival. Malfunction o.....»»
Machine learning cracked the protein-folding problem and won the 2024 Nobel Prize in chemistry
The 2024 Nobel Prize in chemistry recognized Demis Hassabis, John Jumper and David Baker for using machine learning to tackle one of biology's biggest challenges: predicting the 3D shape of proteins and designing them from scratch......»»
Study proposes that proteins can compartmentalize and form droplets inside cells
In physics, a system composed of two substances can be modeled in accordance with classical mixture theory, which considers the fraction corresponding to each constituent and the interactions among constituents. Examples include the coexistence of hi.....»»
High-resolution structural data shows how a supercomplex links mRNA translation and decay
Messenger RNA (mRNA) serves as a blueprint for proteins. When mRNA is no longer needed, it must be degraded. Director Elena Conti and her team at the Max Planck Institute of Biochemistry in Martinsried near Munich have now been able to show that the.....»»
AI-driven approach challenges traditional views on protein structure
In a recently published article in Nature Communications,, a team offers an AI-driven approach to explore structural similarities and relationships across the protein universe. The team includes members from the University of Virginia—including Phi.....»»
Nobel chemistry winner sees engineered proteins solving tough problems
Whether it's battling tumors or breaking down plastic, American scientist David Baker, co-recipient of this year's Nobel Prize in Chemistry, has an answer: engineering proteins that don't naturally exist—a concept once dismissed as "crazy.".....»»
Nobel Prize in chemistry awarded to 3 scientists for work on proteins, building blocks of life
The Nobel Prize in chemistry was awarded Wednesday to three scientists for their breakthrough work predicting and even designing the structure of proteins, the building blocks of life......»»
Nobel Prize in chemistry awarded for work on proteins
The Nobel Prize in chemistry was awarded Wednesday to scientists David Baker, Demis Hassabis and John Jumper for their work with proteins......»»
Prime Big Deal Days tire inflator deals 2024: Snap up these deals and keep your tires safe
We've got all the best Prime Big Deal Days tire inflator deals to help keep you road safe, and we've looked at what you need to consider when buying......»»
Nanopore technique shows transport mechanism of chaperone proteins at the single-molecule level
Proteins control most of the body's functions, and their malfunction can have severe consequences, such as neurodegenerative diseases or cancer. Therefore, cells have mechanisms in place to control protein quality......»»
Comprehensive efforts needed to develop health-promoting learning environments, review finds
Mental ill-health among students in higher education is a growing problem globally. Most efforts implemented to address ill-health involve individual treatment and adjustments to pedagogy. But more can and needs to be done at a structural or environm.....»»
AI and quantum mechanics team up to accelerate drug discovery
Drug discovery is much like working a jigsaw puzzle. The chemical compounds behind drug molecules must be shaped to fit with the proteins in our bodies to produce therapeutic effects. That requirement for a meticulous fit means the creation of new dr.....»»
Lusatia"s transformation from coal is falling short on environmental sustainability, German study finds
A total of 10.3 billion euros of federal funding and several hundred million euros of state funding have been allocated to support the structural transformation of the Lusatian coal district in Brandenburg, Germany. But are the projects targeted by t.....»»
Greening of Antarctica shows how climate change affects the frozen continent
Plant growth is accelerating on the Antarctic Peninsula and nearby islands. When satellites first started peering down on the craggy, glaciated Antarctic Peninsula about 40 years.....»»
Greening of Antartica shows how climate change affects the frozen continent
Plant growth is accelerating on the Antarctic Peninsula and nearby islands. When satellites first started peering down on the craggy, glaciated Antarctic Peninsula about 40 years.....»»
The Secret Alchemy of Making Ice Cream
Ice cream is deceptively simple, but that sweet burst of flavor and soft melt on the tongue is a finicky, frozen science of water, fat, and air delicately held together......»»
Study identifies compounds that extend longevity of Japanese morning glory flowers
The longevity of plant flowers is controlled by genetically programmed mechanisms. After a certain amount of time after flowering, the expression of genes associated with programmed cell death is induced and cellular components such as proteins and n.....»»
Ancient protein structure may have enabled early molecular evolution and diversification
In a finding that offers fresh insights into the early evolution of life on Earth, two RIKEN biologists have conducted lab experiments that have revealed a previously unknown protein fold, which is completely absent in modern proteins......»»
Mathematicians and climate researchers build new models for understanding polar sea ice
Polar sea ice is ever-changing. It shrinks, expands, moves, breaks apart, reforms in response to changing seasons, and rapid climate change. It is far from a homogenous layer of frozen water on the ocean's surface, but rather a dynamic mix of water a.....»»
Apple pulls watchOS 11.1 beta 3 after users report frozen devices
Apple has pulled the watchOS 11 beta 3 update, according to Aaron Perris on X. The update was initially released to developers yesterday, but some users are having problems after installing the latest beta. more….....»»