Structural and functional studies of adhesion receptors disclose intrinsic activation mechanism of orphan GPCRs
G protein-coupled receptors (GPCRs) play a crucial role in cell signal transduction and comprise the largest drug target protein family. Despite recent breakthroughs in structural and pharmacological studies of these receptors, more than 100 GPCRs re.....»»
Promising triazole molecular catalyst enables efficient electroreduction of carbon dioxide to methane
The efficient conversion of carbon dioxide (CO2)—one of the main compounds contributing to climate change—into useful fuels and chemicals is a long sought-after research goal. Recent studies have introduced various catalysts that could be used to.....»»
Studies of migraine’s many triggers offer paths to new therapies
One class of drugs has already found success in treating the painful, common attacks. For Cherise Irons, chocolate, red wine, and aged cheeses are dangerous. So are certain sounds.....»»
T-Mobile, AT&T oppose unlocking rule, claim locked phones are good for users
Carriers fight plan to require unlocking of phones 60 days after activation. T-Mobile and AT&T say US regulators should drop a plan to require unlocking of phones within 60 days o.....»»
How plants compete for light: Researchers discover new mechanism in shade avoidance
Plants that are close together do everything they can to intercept light. This "shade avoidance" response has been extensively researched. It is therefore even more remarkable that researchers from the laboratory of Molecular Biology at Wageningen Un.....»»
3D structures of biomolecules: "Dictionaries" make fluorescence-based data accessible
A research team from Germany and the U.S. led by Heinrich Heine University Düsseldorf (HHU) has developed a data description that can provide results from fluorescence measurements for structural and dynamic modeling of large biomolecules......»»
Attribution studies reveal increasing effects of global warming on fire dynamics and public health
Climate change is increasingly influencing fire behavior worldwide and intensifying fire smoke, endangering public health from air pollution caused by fires. These are the results of two new climate change impact attribution studies, both published i.....»»
Study evaluates overall soil arthropod diversity at different geographic scales
Soil arthropods contribute to terrestrial ecosystem functions and services. Previous studies have mainly focused on specific arthropod and non-arthropod taxonomic groups at various geographic scales. However, the patterns of overall soil arthropod co.....»»
Researchers to explore light and ultrasound therapy for melanoma treatment in pigs
Texas A&M University researchers are collaborating on a new project that studies how ultrasound and light can treat melanomas in pigs......»»
Leveraging skyscraper architecture: New design enhances porosity and structural stability for metal-organic frameworks
The Burj Khalifa, the tallest building in the world, employs advanced construction techniques designed to withstand wind, seismic activity, and its own massive weight. Among these techniques is the "Meta Column System," which plays a pivotal role by.....»»
Key role of structural defects in amorphous solid deformation uncovered
Researchers at the Indian Institute of Science Education and Research (IISER) Pune and the CSIR-National Chemical Laboratory (NCL) Pune have shown that the macroscopic deformation of amorphous solids is controlled by structural defects within the mat.....»»
Abiotic organic synthesis research proposes new mechanism for organic condensation
A Chinese research team has reported the discovery of abiotic organic compounds in the oceanic crust of the Southwest Indian Ridge and proposed a molecular mechanism for organic condensation......»»
Microbiome studies in humans and zoo animals pave the way for new drug development
Microorganisms do not just colonize the body of mammals during infections. Billions of microbes can be found on and in healthy humans and animals at any given time, communicating with each other via chemical signals and thus influencing their health......»»
You Don’t Need Words to Think
Brain studies show that language is not essential for the cognitive processes that underlie thought.....»»
Mechanism of cobalt–manganese catalysts deciphered
Conventional catalysts for hydrogen production via water electrolysis usually contain precious metals and are expensive. However, cheaper alternatives have been developed, for example cobalt–manganese catalysts. They have a high activity and are st.....»»
Research team creates hybrid resonant metasurfaces with configurable structural colors
"Color is crucial," as pop artist Roy Lichtenstein famously said, but the significance of color extends far beyond art. From the creation of Prussian blue—the first synthetic pigment—to quantum dots in modern display technology, colors and their.....»»
Microtubule formation mechanism sheds light on how cells build their internal skeleton
Inside every cell, a network of tiny filaments, called the microtubule cytoskeleton, helps maintain the cell's shape, allows it to divide, and transports vital materials from one part of the cell to another. The filaments that form this network, term.....»»
Red clover seed oil rich in bioactive compounds, study finds
A research team has identified a wealth of bioactive compounds in red clover (Trifolium pratense) seeds and their oil, positioning them as a promising source for functional ingredients in food and health care products. Researchers reveal that red clo.....»»
Why a diabetes drug fell short of anticancer hopes
Studies suggested it could treat cancer, but the clinical trials were a bust. Pamela Goodwin has received hundreds of emails from patients asking if they should take a cheap, read.....»»
Study unveils cobalt(III) reaction mechanism with nitriles, opening pathways for drug development
A research team led by Professor Jaeheung Cho from the Department of Chemistry at UNIST has published a study in the Journal of the American Chemical Society reporting the reaction mechanism of cobalt(III)-based metal complexes with nitrile substance.....»»
Plant stem cells: Understanding the biological mechanism of growth control
Researchers from the University of Freiburg have identified the HAN molecule as an important regulator that controls plant growth in conjunction with WOX5. Understanding this mechanism is relevant for breeding more resilient or higher-yielding crops......»»