Structural and biochemical basis of methylmalonate semialdehyde dehydrogenase ALDH6A1
ALDH6A1, a member of the ALDH family, plays a crucial role in the catabolic pathways of valine and thymine. Dysregulation of ALDH6A1 expression has been linked to a variety of diseases. Methylmalonate semialdehyde dehydrogenase deficiency (MMSDH defi.....»»
Fruit flies give further insight into evolution of male genitalia driven by sexual selection
Fruit flies have provided scientists with new insight into the genetic basis for the rapid evolution of male external genitalia driven by sexual selection......»»
Apple Vision Pro demos for walk-in retail customers start today, reservations to begin next week
Apple will begin taking reservations for Apple Vision Pro demo sessions at Apple Store locations in the US starting Monday. In-store demos start today for walk-in customers on a first come, first serve basis. more….....»»
New study suggests culling animals who "don"t belong" can be a flawed nature conservation practice
New research published today in the journal Science has concluded that eradicating animals on the basis that they are not native in order to protect plant species can be a flawed practice costing millions of dollars, and resulting in the slaughter of.....»»
Structural color ink: Printable, non-iridescent and lightweight
A new way of creating color uses the scattering of light of specific wavelengths around tiny, almost perfectly round silicon crystals. This Kobe University development enables non-fading structural colors that do not depend on the viewing angle and c.....»»
Closing the green gap: A cubic III-nitride active layer with 32% internal quantum efficiency
Color mixing is the process of combining two or more colors: red and green make yellow, blue and red make purple, red and green and blue make white. This process of mixing colors is the basis for the future of solid-state lighting. While currently wh.....»»
Investigating the presence of environmental rare earth elements in activated sludge systems
The pandemic has triggered a major increase in the use of medical facilities and drugs, which has exacerbated pollution in wastewater biochemical treatment systems. Pollution from environmental rare earth elements (REE) has increased due to the wides.....»»
Without clear guidance, SEC’s new rule on incident reporting may be detrimental
The SEC has instituted a set of guidelines “requiring registrants to disclose material cybersecurity incidents they experience and to disclose on an annual basis material information regarding their cybersecurity risk management, strategy, and gove.....»»
Scientists open door to achieving high-precision "slippery structural hydrogel"
Hydrogels inevitably undergo dehydration, structural collapse, and shrinkage deformation due to the uninterrupted evaporation in the atmosphere, thereby losing their flexibility, slipperyness, and manufacturing precision......»»
Copepods—tiny creatures that can help reduce the need for soya imports
In the sea, fish feed on species lower in the food chain. Can these same species form the basis of a new feed industry supplying the fish farming sector?.....»»
Shape-shifting protein study could advance new drug development
Proteins do the heavy lifting of performing biochemical functions in our bodies by binding to metabolites or other proteins to complete tasks. To do this successfully, protein molecules often shape-shift to allow specific binding interactions that ar.....»»
Two new databases combine computer science and pharmaceutical research
Modern pharmaceutical research generates large amounts of data faster than ever before. To analyze and evaluate this data, it is collected and structured in extensive databases and thus provides the basis for the development of new active ingredients.....»»
Stellantis opts out of Chicago Auto Show but will have its popular Camp Jeep at the New York auto show this spring
Stellantis says it's assessing its presence at U.S. events on a case-by-case basis but will have its popular Camp Jeep at the New York auto show this spring......»»
First step towards synthetic carbon dioxide fixation in living cells
Synthetic biology offers the opportunity to build biochemical pathways for the capture and conversion of carbon dioxide (CO2). Researchers at the Max-Planck-Institute for Terrestrial Microbiology have developed a synthetic biochemical cycle that dire.....»»
BarbNet: Awn phenotyping with advanced deep learning, potential applications in the automation of barley awns sorting
Awns, bristle-like extensions on grass crops like wheat and barley, are vital for protection and seed dispersal, with barbs on their surface playing a crucial role. While the genetic basis of barb formation has been explored through genome-wide assoc.....»»
GPCR structure: Research reveals molecular origins of function for a key drug target
Through an international collaboration, scientists at St. Jude Children's Research Hospital have leveraged data science, pharmacology and structural information to conduct an atomic-level investigation into how each amino acid in the receptor that bi.....»»
New research reveals critical steps in Lassa virus ribonucleoparticle assembly and recruitment
Lassa virus (LASV) is the pathogen that causes Lassa hemorrhagic fever, a disease endemic to West Africa, which causes approximately 5,000 deaths each year. At the CSSB Centre for Structural Systems Biology, the Uetrecht (CSSB, LIV, Uni Siegen), Kosi.....»»
Examining the relationship between the rate of wound healing, the circadian rhythm and cilium length
Nearly every organism on Earth follows a natural circadian rhythm that is coded by your cell's clock genes, which do exactly as you suspect from the name: regulate your body's rhythm on a 24-hour basis......»»
Study discusses impact of factor endowments on technology choice, industrial upgrading
Assistant Professor Liu Zhengwen and Professor Zhang Bo of the School of Economics, together with Professor Justin Yifu Lin from the Institute of New Structural Economics and National School of Development have co-authored an article titled "Endowmen.....»»
Scientists create artificial DNA that can be transcribed by a natural enzyme
The genetic alphabet contains just four letters, referring to the four nucleotides, the biochemical building blocks that comprise all DNA. Scientists have long wondered whether it's possible to add more letters to this alphabet by creating brand-new.....»»
Evidence-based policymaking: New study on international perspectives and best-practice models
In order to tackle challenges facing society, such as the energy transition, digitalization, or pandemics, structured, transparent, and fact-based political decision-making processes are needed. Analysis based on science can provide the basis for bet.....»»