RNA modification: Mechanisms and therapeutic targets
RNA modifications are dynamic and reversible chemical modifications on substrate RNA that regulate mRNA stability, translation, and localization. This review is designed by Dr. Junhong Han and written by his postdoctoral researcher Dr. Lei Qiu and P.....»»
Discovery of new plant protein fold may be seed for anti-cancer drugs
University of Michigan researchers are celebrating their discovery of a new plant biochemistry and its unusual ability to form cyclic peptides—molecules that hold promise in pharmaceuticals as they can bind to challenging drug targets......»»
New research reveals mechanisms of stiffening in paper pulp, could lead to improved recyclability
One of the problems with paper recycling is that the fibers stiffen during the dewatering and drying processes, also known as hornification. The same thing happens to dishcloths, for example; they stiffen over time. New research can now explain the m.....»»
Sumsub Deepfake Detection combats AI-driven identity fraud
Sumsub has launched a Deepfake Detection feature integrated into its Video Identification solution. This comes as AI-powered fraud increasingly targets businesses, not just individual users. Sumsub’s 2023 Identity Fraud Report revealed a 10x in.....»»
Why the UK needs connected strategies for net zero and leveling up
The Government's Net Zero Strategy (2022) calls for more attention to community-based action to meet ambitious targets. Similarly, the recently published report of the All-Party Parliamentary Group for "left behind" neighborhoods, "A neighborhood str.....»»
Clarity needed for businesses to achieve greenhouse gas mitigation, study says
Despite efforts to mitigate the effects of climate change, companies are not set up for success due to conflicting national and sectorial targets and differing availability of abatement options, a new study reveals......»»
UAW says it signed majority of workers at VW plant in Tenn.
VW’s Chattanooga factory is the first of 13 non-union targets in the U.S. where the UAW says it’s secured over 50 percent support......»»
Unlocking artemisinin production secrets in Artemisia annua: The role of DBR2-like gene variations
Artemisia annua is the only known plant source of potent antimalarial artemisinins, and its chemotypes are classified as low- and high-artemisinin producing (LAP and HAP). However, the different mechanisms of artemisinin production by these two chemo.....»»
Manipulating host defenses: Unveiling the role of a powdery mildew effector in grapevine infection
Powdery mildew, caused by Erysiphe necator, is a significant threat to grapevine health, utilizing secreted effector proteins (CSEPs) to suppress plant defenses. Despite knowledge of plant immune mechanisms, the specific roles of E. necator's CSEPs i.....»»
Mozilla targets scummy data brokers with Monitor Plus removal service
Service pledges to automatically remove you from listing sites for $108/year. Enlarge “You may be shocked to find,” the people-search websites pitch, that you or the other person you’re searching for “has a crim.....»»
EU unveils 2040 climate targets in political tightrope act
The EU on Tuesday unveils its climate targets for 2040 and a roadmap for the next stage of its energy transition, four months before European elections and with the bloc reeling from a farmer revolt against green reforms......»»
Shedding light on shadows: Unveiling the impact of low light on tomato disease susceptibility and defense mechanisms
The global challenge of plant disease outbreaks under low light intensities leads to significant crop yield losses, with the mechanisms of low light's impact on plant defense poorly understood. Research has identified high light conditions as enhanci.....»»
Making as a Creative Practice
Matt Zigler is the author of a new book for educators titled "3 Modes of Making." He talks about imitation, modification and innovation as three different modes of student projects, which develop different maker skills. Matt is an artist and educato.....»»
Scientists launch ambitious roadmap for circular carbon plastics economy
Researchers from the Oxford Martin Program on the Future of Plastics, University of Oxford, have outlined ambitious targets to help deliver a sustainable and net zero plastic economy. In a paper published in Nature, the authors argue for a rethinking.....»»
Unveiling and decoding the regulatory mechanisms of secondary cell wall formation
Wood quality is primarily determined by the properties of its secondary cell wall (SCW). Gaining insight into the molecular processes governing SCW development is crucial for the genetic enhancement of wood quality. Although it's established that a m.....»»
Endangered seabird shows surprising individual flexibility to adapt to climate change
How individual animals respond to climate change is key to whether populations will persist or go extinct. Many species are shifting their ranges as the environment warms, but up to now the mechanisms underlying this have been unclear. For Europe's m.....»»
Study reveals mechanisms behind how growing cells maintain their mojo by scaling up biosynthesis
Similar to the way expanding companies increase their work forces, cells must boost their production of internal biomolecules when they grow in size in order to stay healthy. In the 1970s, biologists showed that this scaled-up biosynthesis hinges on.....»»
Researchers develop puffed-up MOFs for improved drug delivery
The spongelike structure of metal-organic frameworks (MOFs) allows these polymers to possibly carry and deliver a range of therapeutic compounds. Now, researchers reporting in ACS Applied Bio Materials have treated a chromium-containing MOF with a do.....»»
Shedding light on grapevine growth: Unraveling the impact of LED light quality on photosynthesis and carbon metabolism
Grapevines, essential for wine and raisins, suffer losses due to poor establishment and decline of newly planted vines. Advances in manipulating nursery light spectra show promise for healthier vines, yet the exact mechanisms are unclear......»»
Salsa"s last dance targets reentry over South Pacific
Launched in 2000, Cluster is a unique constellation of four identical spacecraft investigating the interaction between the sun and Earth's magnetosphere—our shield against the charged gas, energetic particles and magnetic field coming from our star.....»»
NASA"s Lucy ready for 2024 mission milestones
After its successful first asteroid encounter in 2023, NASA's Lucy mission has its sights firmly set on its main targets, the never-before-explored Jupiter Trojan asteroids. In 2024, the Lucy spacecraft will transition from its current orbit around t.....»»