Protein structures signal fresh targets for anticancer drugs
Cell replication in our bodies is triggered by a cascade of molecular signals transmitted between proteins. Compounds that block these signals when they run amok show potential as cancer drugs......»»
Scientists unlock the secrets of how a key protein converts DNA into RNA
Researchers at the Department of Energy's SLAC National Accelerator Laboratory have uncovered new insights into the fundamental mechanisms of RNA polymerase II (Pol II), the protein responsible for transcribing DNA into RNA. Their study shows how the.....»»
Protein mutant stability can be inferred from AI-predicted structures
Researchers at the Center for Algorithmic and Robotized Synthesis within the Institute for Basic Science have taken a significant step forward in understanding the stability of proteins by leveraging the power of AI......»»
Study shows an electrically-activated protein regulates spermatogenesis
Frankenstein's monster was brought to life by the judicious application of a little electricity; and a surprising number of processes in our bodies are regulated by electrical currents too. Now, researchers from Japan reveal that electricity may play.....»»
Compounds from nucleic acids in food show anticancer effects
When people eat, they ingest the nucleic acids that reside in all living things. The compounds in these acids could inhibit the growth of cancer cells, according to findings published in PLOS ONE by Osaka Metropolitan University Associate Professor A.....»»
New knowledge about cell receptors paves the way for future drugs against intestinal tumors
A new study from Karolinska Institutet published in Nature Communications provides valuable insights into the activation of receptors on the cell surface. The knowledge could lead to new targeted therapies and drugs against intestinal tumors, among o.....»»
Supercomputer simulations reveal the nature of turbulence in black hole accretion disks
Researchers at Tohoku University and Utsunomiya University have made a breakthrough in understanding the complex nature of turbulence in structures called accretion disks surrounding black holes, using state-of-the-art supercomputers to conduct the h.....»»
Researchers map 50,000 of DNA"s mysterious "knots" in the human genome
Researchers have mapped 50,000 of DNA's mysterious "knots" in the human genome. The innovative study of DNA's hidden structures may open up new approaches for treatment and diagnosis of diseases, including cancer......»»
Google AI reintroduces human image generation after historical accuracy outcry
Ars testing shows some historical prompts no longer generate artificially diverse scenes. Imagen 3's vision of a basketball-playing president is a bit akin to the Fresh Prince'.....»»
Chloroplast manipulation: A new strategy in pathogen warfare uncovered
A recent study has unveiled the sophisticated methods pathogens use to weaken plant defenses. It shows how a pathogen's effector protein targets the chloroplast protein StFC-II, increasing its levels in chloroplasts and reducing the plant's ability t.....»»
Simulation model shows ribosome tunnel"s impact on protein structures
Researchers at University of Tsukuba have developed a new model that simulates the internal environment of a ribosome—the cellular site of protein synthesis. Using computer simulations, they have analyzed the structures of various proteins within t.....»»
Apple"s 15-inch MacBook Air M3 is back down to $1,049 for Labor Day 2024
Labor Day sales have started early, with a fresh price drop on Apple's latest MacBook Air. Save $250 on the 15-inch M3 model.Grab record low prices on M3 MacBook Air models.Amazon's record low price on the M3 15-inch MacBook Air is back heading into.....»»
FAA targets reckless drone pilots with fines totaling $341K
The Federal Aviation Administration has dropped some figures relating to the cost of fines for drone pilots who refuse to follow the rules......»»
Fires in Brazil"s Sao Paulo state under control: authorities
Fires that have razed thousands of hectares of forest in Brazil's Sao Paulo state have been brought under control, authorities said Monday, though an alert for fresh blazes remained in place......»»
Dual protein analysis approach provides potential way to slow cancer growth
Fighting cancer effectively often involves stopping cancer cells from multiplying, which requires understanding proteins that the cells rely on to survive. Protein profiling plays a critical role in this process by helping researchers identify protei.....»»
Dissecting caspase-2-mediated cell death: From intrinsic PIDDosome activation to chemical modulation
Caspase-2, an initiator caspase, plays a critical role in programmed cell death in response to certain cellular stresses. Its activation is facilitated by the PIDDosome, a multi-protein complex that assembles under conditions of genotoxic stress. Des.....»»
Proof-of-concept study demonstrates mid-infrared computational temporal ghost imaging
Ghost imaging in the time domain allows for reconstructing fast temporal objects using a slow photodetector. The technique involves correlating random or pre-programmed probing temporal intensity patterns with the integrated signal measured after mod.....»»
Study reveals bioactive power of a natural spearmint compound against weeds
A recent study reveals the natural compound (-)-carvone in spearmint as a potent and sustainable alternative to chemical herbicides. This research demonstrates how (-)-carvone targets and degrades microtubules in weeds, inducing cell death and inhibi.....»»
What makes a supercluster?
By eye, it's impossible to pick out the exact boundaries of the superclusters, which are among the largest structures in the universe. But that's because they are not defined by their edges, but by the common motion of their components......»»
How engineered walnuts combat drought through grafting
Drought is a major threat to walnut production globally, often resulting in lower yields and weaker trees. While grafting has traditionally been used to improve the resilience of fruit and nut trees, the exact mechanisms of signal transfer between ro.....»»
Nuclei: Open-source vulnerability scanner
Nuclei is a fast and customizable open-source vulnerability scanner powered by YAML-based templates. With its flexible templating system, Nuclei can be adapted to perform various security checks. It can send requests to multiple targets using customi.....»»