Protein machinery of respiration becomes visible
Oxygen and sugar are the basis of life for animals, plants, fungi and many bacteria. The metabolic process called respiration makes it possible to convert food into energy for the cells. Biochemist Prof. Dr. Carola Hunte and her team from the Cluster.....»»
Scientists unlock the secrets of how a key protein converts DNA into RNA
Researchers at the Department of Energy's SLAC National Accelerator Laboratory have uncovered new insights into the fundamental mechanisms of RNA polymerase II (Pol II), the protein responsible for transcribing DNA into RNA. Their study shows how the.....»»
Protein mutant stability can be inferred from AI-predicted structures
Researchers at the Center for Algorithmic and Robotized Synthesis within the Institute for Basic Science have taken a significant step forward in understanding the stability of proteins by leveraging the power of AI......»»
Study shows an electrically-activated protein regulates spermatogenesis
Frankenstein's monster was brought to life by the judicious application of a little electricity; and a surprising number of processes in our bodies are regulated by electrical currents too. Now, researchers from Japan reveal that electricity may play.....»»
Chloroplast manipulation: A new strategy in pathogen warfare uncovered
A recent study has unveiled the sophisticated methods pathogens use to weaken plant defenses. It shows how a pathogen's effector protein targets the chloroplast protein StFC-II, increasing its levels in chloroplasts and reducing the plant's ability t.....»»
Astrobotic’s lander didn’t make it to the Moon because of a failed valve
Engineers are redesigning parts of the propulsion system on Astrobotic's next lunar lander. Enlarge / Astrobotic's Peregrine lander, with some of its propellants visible, before shipment from the company's headquarters in Pittsbu.....»»
Simulation model shows ribosome tunnel"s impact on protein structures
Researchers at University of Tsukuba have developed a new model that simulates the internal environment of a ribosome—the cellular site of protein synthesis. Using computer simulations, they have analyzed the structures of various proteins within t.....»»
Dual protein analysis approach provides potential way to slow cancer growth
Fighting cancer effectively often involves stopping cancer cells from multiplying, which requires understanding proteins that the cells rely on to survive. Protein profiling plays a critical role in this process by helping researchers identify protei.....»»
Dissecting caspase-2-mediated cell death: From intrinsic PIDDosome activation to chemical modulation
Caspase-2, an initiator caspase, plays a critical role in programmed cell death in response to certain cellular stresses. Its activation is facilitated by the PIDDosome, a multi-protein complex that assembles under conditions of genotoxic stress. Des.....»»
Research unravels dual role of membrane protein in rice ethylene signal transduction
A research team, led by Professor Zhang Jinsong from the Institute of Genetics and Developmental Biology (IGDB) of the Chinese Academy of Sciences, revealed insights into the mechanism by which the membrane protein MHZ3 collaborates with the ethylene.....»»
A small molecular glue that increases P53 level and suppresses tumor growth in vivo
Molecular glues are typically small chemical molecules that act on the interface between the target protein and the degradation machinery to trigger ternary complex formation. Identification of molecular glues is challenging, and there has been a lac.....»»
Folding iPad and MacBook may both now be arriving in 2027 or 2028
Apple analyst Ming-Chi Kuo, who previously said he expected a folding MacBook to launch in 2026, now says the timeline has been pushed back to 2027 or 2028. He also says that work on a folding iPad is “not yet visible” in Apple’s supply chai.....»»
Cryo-ET study elucidates protein folding helpers in their natural environment
Cryo-electron tomography (cryo-ET), can be used to visualize and analyze cellular structures in their natural environment. Researchers at the MPI of Biochemistry in Martinsried and the University Medical Center Göttingen have now used cryo-ET to stu.....»»
Quality control: Neatly arranging crystal growth to make fine thin films
Table salt and refined sugar look white to our eyes, but that is only because their individual colorless crystals scatter visible light. This feature of crystals is not always desirable when it comes to materials for optical and electrical devices, h.....»»
Researchers observe Floquet states in colloidal nanoplatelets driven by visible pulses
Solution-processed semiconductor nanocrystals are also called colloidal quantum dots (QDs). While the concept of size-dependent quantum effects had long been known to physicists, a sculpture of the theory into real nanodimensional objects remained im.....»»
Comparing methods for extracting edible protein from mealworms
Edible insects are emerging as an alternative protein source that has various benefits compared with conventional animal sources. New research published in the Journal of Food Science compared four different methods for extracting protein from mealwo.....»»
Researchers teach artificial intelligence about frustration in protein folding
Scientists have found a new way to predict how proteins change their shape when they function, which is important for understanding how they work in living systems. While recent artificial intelligence (AI) technology has made it possible to predict.....»»
Project Helianthus—a solar-sail-driven geomagnetic storm tracker
Solar storms captured the imagination of much of the American public earlier this year when auroras were visible well south of their typical northern areas. As the sun ramps into another solar cycle, those storms will become more and more common, and.....»»
Exploring Huntington"s disease: Researchers discover that protein aggregates poke holes in the nuclear membrane
Researchers at Utrecht University in the Netherlands have identified a new way in which the toxic protein aggregates associated with Huntington's disease may damage nerve cells and cause them to die......»»
Newly discovered protein stops DNA damage
Researchers from Western University have discovered a protein that has the never-before-seen ability to stop DNA damage in its tracks. The finding could provide the foundation for developing everything from vaccines against cancer, to crops that can.....»»
Surprise finding in study of environmental bacteria could advance search for better antibiotics
In what they labeled a "surprising" finding, Johns Hopkins Medicine researchers studying bacteria from freshwater lakes and soil say they have determined a protein's essential role in maintaining the germ's shape. Because the integrity of a bacterial.....»»