Promising Mpox Drug Fails in Trials as Virus Spreads
In a trial in the Democratic Republic of the Congo, the drug tecovirimat, also known as TPOXX, was found to be no better than placebo at clearing mpox lesions......»»
Peer-brokered sales central to illegal drug trade
The thought of illegal drug sales evokes images of deals done on shady street corners. But a new study from Case Western Reserve University exposes a critical but underreported element of the illegal drug market: so-called "peer-brokered" sales......»»
Dynamic tracking technique can reduce noise in gravitational-wave detectors to peer deeper into the cosmos
Researchers have shown that optical spring tracking is a promising way to improve the signal clarity of gravitational-wave detectors. The advance could one day allow scientists to see farther into the universe and provide more information about how b.....»»
Russian court sentences kingpin of Hydra drug marketplace to life in prison
The underground marketplace distributed more than a metric ton of narcotics. A Russian court has issued a life sentence to a man found guilty of being the kingpin of a dark web dr.....»»
Peat-bog fungi produce substances that kill tuberculosis-causing bacteria
An analysis of fungi collected from peat bogs has identified several species that produce substances toxic to the bacterium that causes the human disease tuberculosis. The findings suggest that one promising direction for development of better treatm.....»»
Open-source platform supports large imaging data analysis of single cell responses to manipulation
Modern day drug discovery is shifting from single end point assays to more complex phenotypic assays that query single cell and population responses to chemicals and genetic manipulation......»»
Raw milk producer optimistic after being shut down for bird flu detection
A second lot of milk was recalled after testing of retail products came back positive. Bird flu has landed on a California farm that shuns virus-killing pasteurization, leading to.....»»
New understanding of a cancer-relevant protein reveals opportunities for drug discovery
A new approach to targeting a protein involved in cell division, which can misfunction in cancer, has revealed new insights into how it functions......»»
Modified ribosomes could be a possible mechanism of antibiotic resistance
Bacteria modify their ribosomes when exposed to widely used antibiotics, according to research published in Nature Communications. The subtle changes might be enough to alter the binding site of drug targets and constitute a possible new mechanism of.....»»
Parasite genome analysis provides a new approach to predicting malaria drug resistance
Researchers at University of California San Diego analyzed the genomes of hundreds of malaria parasites to determine which genetic variants are most likely to confer drug resistance......»»
Scientists synthesize unsymmetrical ureas using non-phosgene method
Unsymmetrical ureas can form multiple stable hydrogen bonds with proteins. Since drugs containing urea functional groups display unique biological activities when interacting with their targets, they play an important role in drug development and med.....»»
Apple fails to ride global 2024 smartphone boom with Apple Intelligence
Despite the launch of Apple Intelligence, Apple has not seen the same growth in the recovering smartphone market as other players — but that's expected to change in 2025.Apple Intelligence's Siri animation on an iPhoneThroughout 2024, reports of sm.....»»
From days to hours: A faster way to make a promising new catalyst
Scientists have discovered a faster, more sustainable method for making metal-encapsulated covalent organic frameworks (COFs), materials that have the potential to play a crucial role in catalysis, energy storage, and chemical sensing......»»
Scientists successfully use harmless viruses to investigate the nervous system in frogs
Virus. When you hear the word, you probably shudder. But not all viruses are bad or cause disease. Some are even used for therapeutic applications or vaccination. In basic research, they are often employed to infect certain cells, genetically modify.....»»
Cobalt ions, not covalent organic frameworks themselves, drive catalytic activity, study finds
Covalent organic frameworks (COFs) are less stable as catalysts than previously thought but remain highly active. COFs are promising designer catalysts, for example for the sustainable production of chemicals and fuels. Their properties can be adjust.....»»
Trump targets Mexico and Canada with tariffs, plus an extra 10% for China
Tariffs are retaliation for drug trafficking and illegal migration. Donald Trump has said he will impose tariffs of 25 percent on all imports from Canada and Mexico, and an extra.....»»
X-ray measurements reveal an unexpected role for copper in photocatalysts
Copper is a promising catalyst for sustainably converting carbon dioxide into substances with more electrons (called reduced species). This is an important step in converting carbon dioxide into fuels. This reaction is often initiated by electrical e.....»»
Brazil"s antitrust regulator is set to fine Apple if in-app purchase restrictions aren"t lifted
Apple has only 20 days to open up in-app purchases, or it could face $43k in fines per day if it fails to comply with the Brazil antitrust regulator's ruling.Apple ParkIn 2022, e-commerce merchant MercadoLibre filed an antitrust complaint with Brazil.....»»
DOJ wraps up ad tech trial: Google is “three times” a monopolist
Google argued DOJ proved the "exact opposite" of existence of ad tech monopoly. One of the fastest monopoly trials on record wound down Monday, as US District Court Judge Leonie B.....»»
Spin-powered crystals dramatically improve water splitting process for clean hydrogen production
Water splitting—breaking water molecules into hydrogen and oxygen—is a promising pathway to sustainable energy. However, this process has long been challenged by the slow chemical kinetics of the oxygen evolution reaction that make hydrogen produ.....»»
Raw milk recalled for containing bird flu virus, California reports
One more reason drinking raw milk is a bad idea. Bird flu virus has been found in a batch of raw—unpasteurized—milk sold in California, prompting a recall issued at the state'.....»»