Picky proteins: Understanding yeast adaptor protein selectivity
The cellular membrane controls the passage of substances in and out of the cell. Some larger cargo, such as membrane proteins, nutrients, and pathogens, enter the cell via a process known as clathrin-mediated endocytosis......»»
An elegant switch regulates production of protein variants during cell division
Our cells contain thousands of proteins that have gone largely undetected and unstudied until recent years: these are variants of known proteins, which cells can make when their protein-building machinery interacts differently with the same stretch o.....»»
The Canadian Arctic shows that understanding the effects of climate change requires long-term vision
Embrace change, they say, or become a casualty. This adage weighed heavily on my mind during my latest research trip to the Arctic. Repeatedly, I found myself clutching the .303 caliber rifle over my shoulder—a piece of equipment I once considered.....»»
Enhancing recombinant protein expression in lettuce
Recombinant proteins are crucial in pharmaceutical and other industries. A production method uses plants as hosts in transient protein expression systems. Researchers at the University of Tsukuba developed a technique to increase recombinant protein.....»»
Study offers insights into how to mitigate carbon build-up on catalysts to improve greenhouse gas to energy conversion
Against the backdrop of the energy transition and the fight against climate change, a study published in the journal Angewandte Chemie International Edition offers a key to understanding how to improve the efficiency of processes that convert greenho.....»»
Researcher finds special proteins are key when antibiotic resistance spreads
Antibiotic resistance is a growing public health problem globally. The problem is exacerbated by the fact that some bacteria that have become resistant to antibiotics have the ability to spread that resistance to other bacteria via secretion systems......»»
Nissan tech center volunteers cut loose after work: Wrenching, racing and learning
Doing hands-on mechanical work or driving an Acceleration Team vehicle in a race is more than just a way to have a little fun at work, team members say. It broadens their technical understanding of how cars work as well as how other teams within Niss.....»»
Understanding the relationship between food waste, climate change and an aging population
Producing food and getting it to people's plates entails a significant expenditure of energy and resources. Unfortunately, approximately one third of all food produced globally is not consumed and discarded. Hence, to build sustainable societies, it.....»»
Team achieves successful reproduction of hematopoietic stem cell developmental process in an in vitro culture system
Researchers at Kumamoto University have achieved a notable advancement in stem cell biology by reproducing the developmental process of hematopoietic stem cells (HSCs) in vitro. This culture system not only enhances our understanding of how HSCs deve.....»»
Single-molecule imaging reveals aberrant DNA-binding dynamics of cancer-linked chromatin remodelers
Biophysical chemists from the National University of Singapore (NUS) have uncovered a previously hidden landscape that governs the intracellular organization and dynamics of SWI/SNF chromatin remodelers, an important class of protein complexes that c.....»»
Fast super-resolved microscopy enables structured illumination and extended depth detection
Fluorescence microscopy is a powerful tool in biology, allowing researchers to visualize the intricate world of cells and tissues at a molecular level. While this technique has revolutionized our understanding of biological processes, imaging large a.....»»
Researchers find new role for protein in combating age-related diseases
McMaster University researchers have discovered a previously unknown cell-protecting function of a protein, which could open new avenues for treating age-related diseases and lead to healthier aging overall......»»
New study reveals a global consensus on what democracy means
Most people in most countries state that they wish to have a democratic government. But the definition of democracy has been constantly contested. Without understanding what people really mean by democracy, the concept is vulnerable to being exploite.....»»
Discovery of key protein for biosynthesis of plant defense steroids could enhance pest control strategies
Researchers at the Max Planck Institute for Chemical Ecology have identified GAME15 as a key protein that regulates the biosynthesis of both steroidal glycoalkaloids and steroidal saponins in plants of the genus Solanum......»»
New benchmark helps solve the hardest quantum problems
From subatomic particles to complex molecules, quantum systems hold the key to understanding how the universe works. But there's a catch: when you try to model these systems, that complexity quickly spirals out of control—just imagine trying to pre.....»»
DNA-binding C2H2 zinc finger proteins also regulate RNA processing, researchers discover
Researchers at the University of Toronto have shown that an important class of DNA-binding factors can also bind to RNA, regulating gene expression through various mechanisms. The study significantly expands our understanding of these proteins' funct.....»»
Protein signaling pathway provides insights into cell migration and cancer metastasis
The innate immune response is the body's first line of defense against infection, and a successful immune defense takes a village: a combination of physical barriers, chemical attacks, and an army of specialized white blood cells. But maintaining and.....»»
Higher oxytocin levels linked to reproductive success and better cooperation in house mice
Researchers have further advanced understanding of social relationships in female mammals, highlighting the critical role oxytocin plays......»»
Cryo-electron microscopy sheds light on endothelin signaling mechanisms
Endothelin is a peptide hormone known for its vasoconstrictive effects. Researchers at University of Tsukuba used cryo-electron microscopy to examine the complex structure of the endothelin receptor and G protein, which are crucial for signal transdu.....»»
The role of compromised cyber-physical devices in modern cyberattacks
Cyber-physical devices are increasingly getting compromised and leveraged by criminal groups and state-sponsored threat actors. Fyodor Yarochkin, Senior Threat Solution Architect with Trend Micro, believes that getting a better understanding of attac.....»»
Understanding landslides: A new model for predicting motion
Along coastal California, the possibility of earthquakes and landslides is commonly prefaced by the phrase, "not if, but when." This precarious reality is now a bit more predictable thanks to researchers at UC Santa Cruz and The University of Texas a.....»»